Statins

RECENT POSTS

New Cholesterol Guidelines Will Lead to Overprescribing Statins, Critics Say

A prescription label for the cholesterol-lowering drug Lipitor, a brand name statin medicine. (Tim Boyle/Getty Images)

A prescription label for the cholesterol-lowering drug Lipitor, a brand name statin medicine. (Tim Boyle/Getty Images)

Last Monday two major groups released a set of new guidelines designed to lower cholesterol. Now, it appears a major component of the guidelines — an online risk calculator — may be flawed, the New York Times reports.

Since the publication of the guidelines, two Harvard Medical School professors “evaluated the guidelines using three large studies that involved thousands of people and continued for at least a decade,” the Times reported. They knew the patients’ health status at the start and then they looked to see how many had had a heart attack or stroke in the next decade. How accurate was the new calculator in predicting risk? From the Times:

The answer was that the calculator overpredicted risk by 75 to 150 percent, depending on the population. A man whose risk was 4 percent, for example, might show up as having an 8 percent risk. With a 4 percent risk, he would not warrant treatment — the guidelines that say treatment is advised for those with at least a 7.5 percent risk and that treatment can be considered for those whose risk is 5 percent.

Continue reading