Study Finds Pesticide Exposure in Pregnancy Linked to Autism



Pregnant women living within a mile of fields where pesticides were applied faced almost double the risk of having a baby who developed autism — compared to women who lived more than a mile away, a new study finds.

U.C. Davis researchers tracked pesticide applications on farms in the Central Valley, near Sacramento, and the Bay Area and matched that data to the addresses of women who lived nearby when they were pregnant.

The fetus tends to be vulnerable to certain kinds of insults,” said Irva Hertz-Picciotto, an environmental epidemiologist at the MIND Institute at U.C. Davis and lead author of the study. “Pesticides may be one of those sets of chemicals that we need to be particularly careful about.

The study was published Monday in Environmental Health Perspectives. Continue reading

How to Better Protect Farmworkers from Pesticides? Bilingual Labels

By Dan Charles, NPR

(Sandy Huffaker/Getty Images)

(Sandy Huffaker/Getty Images)

Advocates for farmworkers, especially those who grow America’s leafy greens and fresh vegetables, are pushing the government to do more to protect those workers from exposure to pesticides.

A 20-year-old regulation — the Worker Protection Standard — is supposed to prevent harmful pesticide exposures on the farm. But activist groups like Farmworker Justice say it falls short, and the Environmental Protection Agency is currently working on a new version.

Pesticides carry warning labels that spell out health risks and how workers should protect themselves — but those labels are usually in English.
A new report from Farmworker Justice points out that under the current rules, farmworkers don’t get nearly as much information about hazardous chemicals they may encounter as, say, factory workers. (Industrial workers are covered by different regulations, issued by the Occupational Safety and Health Administration.)

And then there’s the barrier of language. Pesticides carry warning labels that spell out health risks and how workers should protect themselves — but those labels are usually in English. More than 80 percent of the workers in the “salad bowls” of Salinas, Calif., or Yuma, Ariz., are Hispanic. Many have difficulty communicating in English. Continue reading

UCLA Researchers Find Links Between Parkinson’s Disease and Pesticides

By Sasha Khokha, KQED News Central Valley Bureau Chief

A new study from UCLA is the latest addition to a growing body of research linking pesticides and Parkinson’s disease.

UCLA neurologists examined hundreds of Parkinson’s patients in the Central Valley, where rural residents may have been exposed to a fungicide called benomyl. It was widely used on crops like almonds, apples, and berries before the EPA banned it a decade ago.

The study finds the pesticide triggered cellular changes, preventing a key enzyme from keeping check on a naturally occurring toxin that damages neurons in the brain.

But more importantly, researchers found that process may be at play even in Parkinson’s patients who have not been exposed to pesticides. “So it’s really the mechanism by which it works that is of particular interest to us,” UCLA neurology professor Dr. Jeff Bronstein told me, “because we think there are going to be other things in the environment — and other genetic variations — that may lead us to one of the causes of Parkinson’s disease.”

Here’s more from the UCLA press release:

Benomyl exposure, they say, starts a cascade of cellular events that may lead to Parkinson’s. The pesticide prevents an enzyme called ALDH (aldehyde dehydrogenase) from keeping a lid on DOPAL, a toxin that naturally occurs in the brain. When left unchecked by ALDH, DOPAL accumulates, damages neurons and increases an individual’s risk of developing Parkinson’s.
The investigators believe their findings concerning benomyl may be generalized to all Parkinson’s patients. Developing new drugs to protect ALDH activity, they say, may eventually help slow the progression of the disease, whether or not an individual has been exposed to pesticides.

Bronstein’s team tested the pesticide on transparent zebrafish in the lab, where they could watch its impact on neurons tinted with a fluorescent dye.

The new study appears in the latest online edition of the Proceedings of the National Academy of Sciences.

Listen to Sasha Khokha’s story: