For HIV Survivors, Pandemic Is Sad Reminder of Early Days of AIDS
The Big Science and Environment Stories of the Decade
CRISPR Wipes Out HIV in Some Mice
Second Patient is Reported Effectively Cured of HIV
Chinese Scientist Says He's First to Create Genetically Modified Babies Using CRISPR
Molecular Scissors May Help Potentially Cure AIDS in the Future
Sponsored
window.__IS_SSR__=true
window.__INITIAL_STATE__={"attachmentsReducer":{"audio_0":{"type":"attachments","id":"audio_0","imgSizes":{"kqedFullSize":{"file":"https://ww2.kqed.org/news/wp-content/themes/KQED-unified/img/audio_bgs/background0.jpg"}}},"audio_1":{"type":"attachments","id":"audio_1","imgSizes":{"kqedFullSize":{"file":"https://ww2.kqed.org/news/wp-content/themes/KQED-unified/img/audio_bgs/background1.jpg"}}},"audio_2":{"type":"attachments","id":"audio_2","imgSizes":{"kqedFullSize":{"file":"https://ww2.kqed.org/news/wp-content/themes/KQED-unified/img/audio_bgs/background2.jpg"}}},"audio_3":{"type":"attachments","id":"audio_3","imgSizes":{"kqedFullSize":{"file":"https://ww2.kqed.org/news/wp-content/themes/KQED-unified/img/audio_bgs/background3.jpg"}}},"audio_4":{"type":"attachments","id":"audio_4","imgSizes":{"kqedFullSize":{"file":"https://ww2.kqed.org/news/wp-content/themes/KQED-unified/img/audio_bgs/background4.jpg"}}},"placeholder":{"type":"attachments","id":"placeholder","imgSizes":{"thumbnail":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-160x96.jpg","width":160,"height":96,"mimeType":"image/jpeg"},"medium":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-800x478.jpg","width":800,"height":478,"mimeType":"image/jpeg"},"large":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-1020x610.jpg","width":1020,"height":610,"mimeType":"image/jpeg"},"fd-lrg":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-1920x1148.jpg","width":1920,"height":1148,"mimeType":"image/jpeg"},"fd-med":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-1180x705.jpg","width":1180,"height":705,"mimeType":"image/jpeg"},"fd-sm":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-960x574.jpg","width":960,"height":574,"mimeType":"image/jpeg"},"post-thumbnail":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-672x372.jpg","width":672,"height":372,"mimeType":"image/jpeg"},"twentyfourteen-full-width":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-1038x576.jpg","width":1038,"height":576,"mimeType":"image/jpeg"},"xxsmall":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-240x143.jpg","width":240,"height":143,"mimeType":"image/jpeg"},"xsmall":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-375x224.jpg","width":375,"height":224,"mimeType":"image/jpeg"},"small":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-520x311.jpg","width":520,"height":311,"mimeType":"image/jpeg"},"xlarge":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-1180x705.jpg","width":1180,"height":705,"mimeType":"image/jpeg"},"full-width":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-1920x1148.jpg","width":1920,"height":1148,"mimeType":"image/jpeg"},"guest-author-32":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-32x32.jpg","width":32,"height":32,"mimeType":"image/jpeg"},"guest-author-50":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-50x50.jpg","width":50,"height":50,"mimeType":"image/jpeg"},"guest-author-64":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-64x64.jpg","width":64,"height":64,"mimeType":"image/jpeg"},"guest-author-96":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-96x96.jpg","width":96,"height":96,"mimeType":"image/jpeg"},"guest-author-128":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-128x128.jpg","width":128,"height":128,"mimeType":"image/jpeg"},"detail":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-150x150.jpg","width":150,"height":150,"mimeType":"image/jpeg"},"kqedFullSize":{"file":"https://ww2.kqed.org/wp-content/uploads/sites/10/2018/01/GettyImages-896326950-e1514998105161.jpg","width":1920,"height":1148}}},"science_1966686":{"type":"attachments","id":"science_1966686","meta":{"index":"attachments_1591205162","site":"science","id":"1966686","found":true},"title":"GettyImages-2774185 (1) (1)","publishDate":1593643769,"status":"inherit","parent":1966675,"modified":1593708231,"caption":"A man looks at a memorial with engraved names of AIDS victims on Dec. 1, 2003, at the National AIDS Memorial Grove in San Francisco.","credit":"Justin Sullivan/Getty Images","description":null,"imgSizes":{"medium":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2020/07/GettyImages-2774185-1-1-800x528.jpg","width":800,"height":528,"mimeType":"image/jpeg"},"large":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2020/07/GettyImages-2774185-1-1-1020x674.jpg","width":1020,"height":674,"mimeType":"image/jpeg"},"thumbnail":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2020/07/GettyImages-2774185-1-1-160x106.jpg","width":160,"height":106,"mimeType":"image/jpeg"},"medium_large":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2020/07/GettyImages-2774185-1-1-768x507.jpg","width":768,"height":507,"mimeType":"image/jpeg"},"1536x1536":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2020/07/GettyImages-2774185-1-1-1536x1014.jpg","width":1536,"height":1014,"mimeType":"image/jpeg"},"post-thumbnail":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2020/07/GettyImages-2774185-1-1-672x372.jpg","width":672,"height":372,"mimeType":"image/jpeg"},"twentyfourteen-full-width":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2020/07/GettyImages-2774185-1-1-1038x576.jpg","width":1038,"height":576,"mimeType":"image/jpeg"},"kqedFullSize":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2020/07/GettyImages-2774185-1-1.jpg","width":1920,"height":1268}},"fetchFailed":false,"isLoading":false},"science_1952606":{"type":"attachments","id":"science_1952606","meta":{"index":"attachments_1591205162","site":"science","id":"1952606","found":true},"title":"Pluto-New-Horizons","publishDate":1576892638,"status":"inherit","parent":1952464,"modified":1576892831,"caption":"High-resolution image of Pluto captured by NASA’s New Horizons spacecraft in January 2016.","credit":"NASA","description":"High-resolution image of Pluto captured by NASA’s New Horizons spacecraft in January 2016.","imgSizes":{"thumbnail":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/12/Pluto-New-Horizons-160x104.jpg","width":160,"height":104,"mimeType":"image/jpeg"},"medium":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/12/Pluto-New-Horizons-800x519.jpg","width":800,"height":519,"mimeType":"image/jpeg"},"medium_large":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/12/Pluto-New-Horizons-768x499.jpg","width":768,"height":499,"mimeType":"image/jpeg"},"large":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/12/Pluto-New-Horizons-1020x662.jpg","width":1020,"height":662,"mimeType":"image/jpeg"},"post-thumbnail":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/12/Pluto-New-Horizons-672x372.jpg","width":672,"height":372,"mimeType":"image/jpeg"},"twentyfourteen-full-width":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/12/Pluto-New-Horizons-1038x576.jpg","width":1038,"height":576,"mimeType":"image/jpeg"},"kqedFullSize":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/12/Pluto-New-Horizons.jpg","width":1180,"height":766}},"fetchFailed":false,"isLoading":false},"science_1944503":{"type":"attachments","id":"science_1944503","meta":{"index":"attachments_1591205162","site":"science","id":"1944503","found":true},"title":"3d render of dna structure, abstract background","publishDate":1562110059,"status":"inherit","parent":1944497,"modified":1562110105,"caption":null,"credit":"DigitalGenetics/via Adobe","description":null,"imgSizes":{"thumbnail":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/07/DNA_AdobeStock_64573096-1200x800-160x107.jpeg","width":160,"height":107,"mimeType":"image/jpeg"},"medium":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/07/DNA_AdobeStock_64573096-1200x800-800x533.jpeg","width":800,"height":533,"mimeType":"image/jpeg"},"medium_large":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/07/DNA_AdobeStock_64573096-1200x800-768x512.jpeg","width":768,"height":512,"mimeType":"image/jpeg"},"large":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/07/DNA_AdobeStock_64573096-1200x800-1020x680.jpeg","width":1020,"height":680,"mimeType":"image/jpeg"},"complete_open_graph":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/07/DNA_AdobeStock_64573096-1200x800-1200x800.jpeg","width":1200,"height":800,"mimeType":"image/jpeg"},"post-thumbnail":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/07/DNA_AdobeStock_64573096-1200x800-672x372.jpeg","width":672,"height":372,"mimeType":"image/jpeg"},"twentyfourteen-full-width":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/07/DNA_AdobeStock_64573096-1200x800-1038x576.jpeg","width":1038,"height":576,"mimeType":"image/jpeg"},"kqedFullSize":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/07/DNA_AdobeStock_64573096-1200x800.jpeg","width":1200,"height":800}},"fetchFailed":false,"isLoading":false},"science_1938726":{"type":"attachments","id":"science_1938726","meta":{"index":"attachments_1591205162","site":"science","id":"1938726","found":true},"title":"timbrown","publishDate":1551805052,"status":"inherit","parent":1938724,"modified":1551805107,"caption":"Timothy Ray Brown (L), also known as “The Berlin Patient”, considered the first person to be cured of HIV.","credit":"GERARD JULIEN/AFP/GETTYIMAGES","description":null,"imgSizes":{"thumbnail":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/03/timbrown-160x90.jpg","width":160,"height":90,"mimeType":"image/jpeg"},"medium":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/03/timbrown-800x450.jpg","width":800,"height":450,"mimeType":"image/jpeg"},"medium_large":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/03/timbrown-768x432.jpg","width":768,"height":432,"mimeType":"image/jpeg"},"large":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/03/timbrown-1020x574.jpg","width":1020,"height":574,"mimeType":"image/jpeg"},"post-thumbnail":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/03/timbrown-672x372.jpg","width":672,"height":372,"mimeType":"image/jpeg"},"twentyfourteen-full-width":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/03/timbrown-1024x576.jpg","width":1024,"height":576,"mimeType":"image/jpeg"},"guest-author-32":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/03/timbrown-32x32.jpg","width":32,"height":32,"mimeType":"image/jpeg"},"guest-author-50":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/03/timbrown-50x50.jpg","width":50,"height":50,"mimeType":"image/jpeg"},"guest-author-64":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/03/timbrown-64x64.jpg","width":64,"height":64,"mimeType":"image/jpeg"},"guest-author-96":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/03/timbrown-96x96.jpg","width":96,"height":96,"mimeType":"image/jpeg"},"guest-author-128":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/03/timbrown-128x128.jpg","width":128,"height":128,"mimeType":"image/jpeg"},"kqedFullSize":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2019/03/timbrown.jpg","width":1024,"height":576}},"fetchFailed":false,"isLoading":false},"science_1935025":{"type":"attachments","id":"science_1935025","meta":{"index":"attachments_1591205162","site":"science","id":"1935025","found":true},"title":"HONG KONG-CHINA-SCIENCE-GENETICS-RESEARCH-ETHICS","publishDate":1543528095,"status":"inherit","parent":1934916,"modified":1543528157,"caption":"Chinese scientist He Jiankui speaks at the Second International Summit on Human Genome Editing in Hong Kong on November 28, 2018. ","credit":"ANTHONY WALLACE/AFP/Getty Images","description":"(Photo by Anthony WALLACE / AFP) ","imgSizes":{"thumbnail":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-160x107.jpg","width":160,"height":107,"mimeType":"image/jpeg"},"medium":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-800x533.jpg","width":800,"height":533,"mimeType":"image/jpeg"},"medium_large":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-768x512.jpg","width":768,"height":512,"mimeType":"image/jpeg"},"large":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-1020x680.jpg","width":1020,"height":680,"mimeType":"image/jpeg"},"complete_open_graph":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-1200x800.jpg","width":1200,"height":800,"mimeType":"image/jpeg"},"fd-lrg":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-1920x1280.jpg","width":1920,"height":1280,"mimeType":"image/jpeg"},"fd-med":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-1180x787.jpg","width":1180,"height":787,"mimeType":"image/jpeg"},"fd-sm":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-960x640.jpg","width":960,"height":640,"mimeType":"image/jpeg"},"post-thumbnail":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-672x372.jpg","width":672,"height":372,"mimeType":"image/jpeg"},"twentyfourteen-full-width":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-1038x576.jpg","width":1038,"height":576,"mimeType":"image/jpeg"},"xxsmall":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-240x160.jpg","width":240,"height":160,"mimeType":"image/jpeg"},"xsmall":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-375x250.jpg","width":375,"height":250,"mimeType":"image/jpeg"},"small":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-520x347.jpg","width":520,"height":347,"mimeType":"image/jpeg"},"xlarge":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-1180x787.jpg","width":1180,"height":787,"mimeType":"image/jpeg"},"full-width":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-1920x1280.jpg","width":1920,"height":1280,"mimeType":"image/jpeg"},"guest-author-32":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-32x32.jpg","width":32,"height":32,"mimeType":"image/jpeg"},"guest-author-50":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-50x50.jpg","width":50,"height":50,"mimeType":"image/jpeg"},"guest-author-64":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-64x64.jpg","width":64,"height":64,"mimeType":"image/jpeg"},"guest-author-96":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-96x96.jpg","width":96,"height":96,"mimeType":"image/jpeg"},"guest-author-128":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-128x128.jpg","width":128,"height":128,"mimeType":"image/jpeg"},"detail":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760-150x150.jpg","width":150,"height":150,"mimeType":"image/jpeg"},"kqedFullSize":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2018/11/GettyImages-1066011760.jpg","width":4720,"height":3147}},"fetchFailed":false,"isLoading":false},"science_8111":{"type":"attachments","id":"science_8111","meta":{"index":"attachments_1591205162","site":"science","id":"8111","found":true},"title":"AIDSquilt","publishDate":1378483182,"status":"inherit","parent":8108,"modified":1378483182,"caption":"We will know in a few years if a new treatment will end up being a cure for AIDS. This image of the AIDS quilt is courtesy of Wikimedia Commons.","credit":null,"description":null,"imgSizes":{"kqedFullSize":{"file":"https://ww2.kqed.org/app/uploads/sites/35/2013/09/AIDSquilt.jpg","width":637,"height":351}},"fetchFailed":false,"isLoading":false}},"audioPlayerReducer":{"postId":"stream_live"},"authorsReducer":{"byline_science_1944497":{"type":"authors","id":"byline_science_1944497","meta":{"override":true},"slug":"byline_science_1944497","name":"Berly McCoy \u003cbr/> PBS Newshour \u003cbr>","isLoading":false},"byline_science_1938724":{"type":"authors","id":"byline_science_1938724","meta":{"override":true},"slug":"byline_science_1938724","name":"Kate Sheridan\u003cbr />STAT","isLoading":false},"byline_science_1934916":{"type":"authors","id":"byline_science_1934916","meta":{"override":true},"slug":"byline_science_1934916","name":"Rob Stein\u003cbr>\u003cstrong>NPR\u003c/strong>","isLoading":false},"dr-barry-starr":{"type":"authors","id":"6177","meta":{"index":"authors_1591205172","id":"6177","found":true},"name":"Dr. Barry Starr","firstName":"Dr. Barry","lastName":"Starr","slug":"dr-barry-starr","email":"bstarr@thetech.org","display_author_email":false,"staff_mastheads":[],"title":null,"bio":"Dr. Barry Starr (\u003ca href=\"https://twitter.com/geneticsboy\">@geneticsboy\u003c/a>) is a Geneticist-in-Residence at The Tech Museum of Innovation in San Jose, CA and runs their Stanford at The Tech program. The program is part of an ongoing collaboration between the \u003ca href=\"http://genetics.stanford.edu/\">Stanford Department of Genetics\u003c/a> and \u003ca href=\"http://www.thetech.org/\">The Tech Museum of Innovation\u003c/a>. Together these two partners created the \u003ca href=\"http://www.thetech.org/exhibits/permanent/index.php?sGalKey=gtwt&galKey=lt\">Genetics: Technology with a Twist\u003c/a> exhibition.\r\n\r\nYou can also see \u003ca href=\"https://ww2.kqed.org/science/author/dr-barry-starr/\">additional posts by Barry at KQED Science\u003c/a>, and read his \u003ca href=\"http://science.kqed.org/quest/author/dr-barry-starr/\">previous contributions\u003c/a> to \u003ca href=\"http://science.kqed.org/quest/\">QUEST\u003c/a>, a project dedicated to exploring the Science of Sustainability.","avatar":"https://secure.gravatar.com/avatar/4a5680e4c642ea0f0f3041af16018969?s=600&d=blank&r=g","twitter":"geneticsboy","facebook":null,"instagram":null,"linkedin":null,"sites":[{"site":"science","roles":["author"]},{"site":"quest","roles":["subscriber"]}],"headData":{"title":"Dr. Barry Starr | KQED","description":null,"ogImgSrc":"https://secure.gravatar.com/avatar/4a5680e4c642ea0f0f3041af16018969?s=600&d=blank&r=g","twImgSrc":"https://secure.gravatar.com/avatar/4a5680e4c642ea0f0f3041af16018969?s=600&d=blank&r=g"},"isLoading":false,"link":"/author/dr-barry-starr"},"kqedscience":{"type":"authors","id":"6387","meta":{"index":"authors_1591205172","id":"6387","found":true},"name":"KQED Science","firstName":"KQED","lastName":"Science","slug":"kqedscience","email":"kqedscience@gmail.com","display_author_email":false,"staff_mastheads":[],"title":null,"bio":"KQED Science brings you award-winning science and environment coverage from the Bay Area and beyond by the flagship Northern California PBS and NPR affiliate.","avatar":"https://secure.gravatar.com/avatar/5a295ff49cf82a8c0f30937d3f788b2f?s=600&d=blank&r=g","twitter":null,"facebook":null,"instagram":null,"linkedin":null,"sites":[{"site":"science","roles":["contributor"]},{"site":"quest","roles":["editor"]},{"site":"food","roles":["contributor"]}],"headData":{"title":"KQED Science | KQED","description":null,"ogImgSrc":"https://secure.gravatar.com/avatar/5a295ff49cf82a8c0f30937d3f788b2f?s=600&d=blank&r=g","twImgSrc":"https://secure.gravatar.com/avatar/5a295ff49cf82a8c0f30937d3f788b2f?s=600&d=blank&r=g"},"isLoading":false,"link":"/author/kqedscience"},"lesleymcclurg":{"type":"authors","id":"11229","meta":{"index":"authors_1591205172","id":"11229","found":true},"name":"Lesley McClurg","firstName":"Lesley","lastName":"McClurg","slug":"lesleymcclurg","email":"lmcclurg@KQED.org","display_author_email":false,"staff_mastheads":["news","science"],"title":"KQED Health Correspondent","bio":"\u003cspan style=\"font-weight: 400;\">Lesley McClurg is a health correspondent and fill-in host. \u003c/span>\u003cspan style=\"font-weight: 400;\">Her work is regularly rebroadcast on numerous NPR and PBS shows. She has won several regional Emmy awards, a regional and a national Edward R. Murrow award. The Association for Health Journalists awarded Lesley best beat coverage. The Society of Professional Journalists has recognized her reporting several times. The Society of Environmental Journalists spotlighted her ongoing coverage of California's historic drought. \u003c/span>\u003cspan style=\"font-weight: 400;\">Before joining KQED in 2016, she covered food and sustainability for Capital Public Radio, the environment for Colorado Public Radio, and reported for both KUOW and KCTS9 in Seattle. \u003c/span>\u003cspan style=\"font-weight: 400;\">When not hunched over her laptop Lesley enjoys skiing with her toddler, surfing with her husband or scheming their next globetrotting adventure. Before motherhood she relished dancing tango till sunrise. When on deadline she fuels herself almost exclusively on chocolate chips.\u003c/span>\r\n\r\n\u003cspan style=\"font-weight: 400;\"> \u003c/span>","avatar":"https://secure.gravatar.com/avatar/3fb78e873af3312f34d0bc1d60a07c7f?s=600&d=blank&r=g","twitter":"lesleywmcclurg","facebook":null,"instagram":null,"linkedin":null,"sites":[{"site":"arts","roles":["author"]},{"site":"news","roles":["editor"]},{"site":"futureofyou","roles":["editor"]},{"site":"stateofhealth","roles":["author"]},{"site":"science","roles":["editor"]}],"headData":{"title":"Lesley McClurg | KQED","description":"KQED Health Correspondent","ogImgSrc":"https://secure.gravatar.com/avatar/3fb78e873af3312f34d0bc1d60a07c7f?s=600&d=blank&r=g","twImgSrc":"https://secure.gravatar.com/avatar/3fb78e873af3312f34d0bc1d60a07c7f?s=600&d=blank&r=g"},"isLoading":false,"link":"/author/lesleymcclurg"}},"breakingNewsReducer":{},"campaignFinanceReducer":{},"firebase":{"requesting":{},"requested":{},"timestamps":{},"data":{},"ordered":{},"auth":{"isLoaded":false,"isEmpty":true},"authError":null,"profile":{"isLoaded":false,"isEmpty":true},"listeners":{"byId":{},"allIds":[]},"isInitializing":false,"errors":[]},"navBarReducer":{"navBarId":"news","fullView":true,"showPlayer":false},"navMenuReducer":{"menus":[{"key":"menu1","items":[{"name":"News","link":"/","type":"title"},{"name":"Politics","link":"/politics"},{"name":"Science","link":"/science"},{"name":"Education","link":"/educationnews"},{"name":"Housing","link":"/housing"},{"name":"Immigration","link":"/immigration"},{"name":"Criminal Justice","link":"/criminaljustice"},{"name":"Silicon Valley","link":"/siliconvalley"},{"name":"Forum","link":"/forum"},{"name":"The California Report","link":"/californiareport"}]},{"key":"menu2","items":[{"name":"Arts & Culture","link":"/arts","type":"title"},{"name":"Critics’ Picks","link":"/thedolist"},{"name":"Cultural Commentary","link":"/artscommentary"},{"name":"Food & Drink","link":"/food"},{"name":"Bay Area Hip-Hop","link":"/bayareahiphop"},{"name":"Rebel Girls","link":"/rebelgirls"},{"name":"Arts Video","link":"/artsvideos"}]},{"key":"menu3","items":[{"name":"Podcasts","link":"/podcasts","type":"title"},{"name":"Bay Curious","link":"/podcasts/baycurious"},{"name":"Rightnowish","link":"/podcasts/rightnowish"},{"name":"The Bay","link":"/podcasts/thebay"},{"name":"On Our Watch","link":"/podcasts/onourwatch"},{"name":"Mindshift","link":"/podcasts/mindshift"},{"name":"Consider This","link":"/podcasts/considerthis"},{"name":"Political Breakdown","link":"/podcasts/politicalbreakdown"}]},{"key":"menu4","items":[{"name":"Live Radio","link":"/radio","type":"title"},{"name":"TV","link":"/tv","type":"title"},{"name":"Events","link":"/events","type":"title"},{"name":"For Educators","link":"/education","type":"title"},{"name":"Support KQED","link":"/support","type":"title"},{"name":"About","link":"/about","type":"title"},{"name":"Help Center","link":"https://kqed-helpcenter.kqed.org/s","type":"title"}]}]},"pagesReducer":{},"postsReducer":{"stream_live":{"type":"live","id":"stream_live","audioUrl":"https://streams.kqed.org/kqedradio","title":"Live Stream","excerpt":"Live Stream information currently unavailable.","link":"/radio","featImg":"","label":{"name":"KQED Live","link":"/"}},"stream_kqedNewscast":{"type":"posts","id":"stream_kqedNewscast","audioUrl":"https://www.kqed.org/.stream/anon/radio/RDnews/newscast.mp3?_=1","title":"KQED Newscast","featImg":"","label":{"name":"88.5 FM","link":"/"}},"science_1966675":{"type":"posts","id":"science_1966675","meta":{"index":"posts_1591205157","site":"science","id":"1966675","score":null,"sort":[1594018887000]},"guestAuthors":[],"slug":"as-with-covid-19-uncertainty-and-stigma-marked-the-outbreak-of-hiv-now-these-men-navigate-a-new-pandemic","title":"For HIV Survivors, Pandemic Is Sad Reminder of Early Days of AIDS","publishDate":1594018887,"format":"audio","headTitle":"For HIV Survivors, Pandemic Is Sad Reminder of Early Days of AIDS | KQED","labelTerm":{},"content":"\u003cp class=\"p1\">In January, two weeks after Rick Solomon joined the YMCA near his home, he fell ill. The 65-year-old Berkeley resident hoped to spend the month working out, instead he laid in bed wheezing, with crippling muscle aches. He missed several days of work at a small publishing house.\u003c/p>\n\u003cp class=\"p1\">[pullquote size='medium' citation='Dr. Steven Deeks, UCSF']‘I am pretty sure that my patients, my older, primarily gay men who survived the ’80s and ’90s, were the first to effectively shelter in place because they know what a pandemic is.’[/pullquote]“I was sick for most of the month of February with a horrible cough like I’ve never had before,” said Solomon running his fingers through his thick salt and pepper hair. “It went into my chest. I used inhalers for the first time in my life.”\u003c/p>\n\u003cp class=\"p1\">He was never tested for COVID-19 because he hadn’t traveled overseas recently, which was one of the official requirements for testing at the time. And although he has since tested negative for the virus’ antibodies, Solomon still believes he may have caught the bug.\u003c/p>\n\u003cp class=\"p1\">“The test the lab used was not FDA approved,” he said. “So who knows? It was just a different kind of cold.”\u003c/p>\n\u003cp class=\"p1\">Solomon took the antibody test because he wanted to enroll in a study at Zuckerberg San Francisco General Hospital looking at HIV-positive people infected with COVID-19. It’s a topic of special interest to researchers.\u003c/p>\n\u003cp class=\"p1\">“COVID is going to have a major impact on the trajectory of the HIV epidemic,” said Dr. Steven Deeks, a UCSF professor of medicine and HIV researcher. “We just don’t know how.”\u003c/p>\n\u003cfigure id=\"attachment_1966721\" class=\"wp-caption alignright\" style=\"max-width: 527px\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\" wp-image-1966721\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2020/07/SD-ZSF-Photograph-800x534.jpg\" alt=\"Dr. Steven Deeks is a recognized expert on HIV-associated immune dysfunction and its impact on HIV persistence (the “reservoir”) and health during antiretroviral therapy. \" width=\"527\" height=\"351\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/SD-ZSF-Photograph-800x534.jpg 800w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/SD-ZSF-Photograph-1020x680.jpg 1020w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/SD-ZSF-Photograph-160x107.jpg 160w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/SD-ZSF-Photograph-768x512.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/SD-ZSF-Photograph-1536x1025.jpg 1536w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/SD-ZSF-Photograph-1920x1281.jpg 1920w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/SD-ZSF-Photograph.jpg 2048w\" sizes=\"(max-width: 527px) 100vw, 527px\">\u003cfigcaption class=\"wp-caption-text\">Dr. Steven Deeks is a recognized expert on HIV-associated immune dysfunction and its impact on HIV persistence (the “reservoir”) and health during antiretroviral therapy. \u003ccite>(UCSF)\u003c/cite>\u003c/figcaption>\u003c/figure>\n\u003cp class=\"p2\">Some answers may come to light this week at the \u003ca href=\"https://www.aids2020.org/\">\u003cspan class=\"s2\">23rd International AIDS Conference.\u003c/span>\u003c/a> The event was scheduled to happen in San Francisco and Oakland until the coronavirus hit. Now scientists, policymakers, public health experts and patients from around the world will gather virtually. COVID-19 is a central topic on the agenda.\u003c/p>\n\u003cp class=\"p1\">\u003cb>Surprising Positive Trend\u003c/b>\u003c/p>\n\u003cp class=\"p1\">Infectious disease doctors assumed people with HIV would be at higher risk for complications from the novel coronavirus due to a weakened immune system. Plus, the majority of HIV-positive people in the U.S. are older, and many struggle with underlying conditions like heart disease and diabetes, which make illness from COVID-19 infection more severe.\u003c/p>\n\u003cp class=\"p1\">Early in the outbreak, four of Dr. Edward “Lalo” Cachay’s patients were hospitalized for complications with COVID-19. Cachay, a professor of medicine at UC San Diego, feared the worst.\u003c/p>\n\u003cp class=\"p1\">“You could potentially have a very dangerous combination of both biological and social determinants of health,” said Cachay.\u003c/p>\n\u003cp class=\"p1\">HIV patients are not only immunocompromised, many also face psycho-social barriers like poor health insurance and mental illness. But not only did Cachay’s four patients experience good outcomes, this positive trend is playing out across the globe.\u003c/p>\n\u003cfigure id=\"attachment_1966724\" class=\"wp-caption alignright\" style=\"max-width: 438px\">\u003ca href=\"https://ww2.kqed.org/app/uploads/sites/35/2020/07/Cachay-Edward-_white-coat-2-e1593709402341.jpg\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\" wp-image-1966724\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2020/07/Cachay-Edward-_white-coat-2-e1593709402341-800x833.jpg\" alt=\"Edward “Lalo” Cachay, a professor of medicine at UCSD., smiles in a university portrait. He has warm brown eyes behind brown glasses and a closely trimmed, salt-and-pepper beard and mustache.\" width=\"438\" height=\"456\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/Cachay-Edward-_white-coat-2-e1593709402341-800x833.jpg 800w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/Cachay-Edward-_white-coat-2-e1593709402341-1020x1062.jpg 1020w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/Cachay-Edward-_white-coat-2-e1593709402341-160x167.jpg 160w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/Cachay-Edward-_white-coat-2-e1593709402341-768x800.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/Cachay-Edward-_white-coat-2-e1593709402341.jpg 1281w\" sizes=\"(max-width: 438px) 100vw, 438px\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Edward “Lalo” Cachay, a professor of medicine at UCSD. \u003ccite>(UCSD)\u003c/cite>\u003c/figcaption>\u003c/figure>\n\u003cp class=\"p1\">“People with HIV are radically underrepresented in the different cohorts coming from Europe and China with very advanced, severe forms of COVID-19,” Cachay said.\u003c/p>\n\u003cp class=\"p1\">Two small studies from \u003ca href=\"https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(20)30164-8/fulltext\">\u003cspan class=\"s1\">Spain\u003c/span>\u003c/a> and \u003ca href=\"https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(20)30164-8/fulltext\">\u003cspan class=\"s1\">Italy\u003c/span>\u003c/a> show that HIV-positive people infected with COVID-19 did not fare worse than those without HIV. Scientists are not sure why.\u003c/p>\n\u003cp class=\"p1\">\u003cb>More Questions Than Answers\u003c/b>\u003c/p>\n\u003cp class=\"p1\">“The bottom line is we have no idea,” said Deeks. “We have lots of interesting questions, lots of important questions, and lots of anecdotes. But at the end of day, we don’t have much data at all.”\u003c/p>\n\u003cp class=\"p1\">Cachay hopes a study he is involved in will offer concrete answers. He’s partnering with scientists at the Fred Hutchinson Cancer Research Center and the University of Washington to answer some key questions: \u003cspan class=\"s1\">What factors might predict which HIV patients are most at risk? Do HIV patients who contract COVID-19 suffer severe illness? And are mortality rates higher in HIV patients who contract the novel\u003c/span> \u003cspan class=\"s1\">coronavirus? \u003c/span>\u003c/p>\n\u003cp class=\"p2\">“I hope this study will help us disentangle the data more,” said Cachay.\u003c/p>\n\u003cp class=\"p1\">Some experts theorize daily HIV meds might offer some protection against the coronavirus. Others wonder if the immune system of people with HIV is altered in a way that offers some resilience. Or, perhaps, experience helps.\u003c/p>\n\u003cp class=\"p1\">“I am pretty sure that my patients, my older, primarily gay men who survived the ’80s and ’90s, were the first to effectively shelter in place because they know what a pandemic is,” said Deeks. “They know how a virus can ravage a community. They know how important social distancing is.”\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp class=\"p1\">Dr. Michael Gottlieb, the UCLA HIV physician who identified the first cluster of HIV cases in 1981, agrees.\u003c/p>\n\u003cp class=\"p1\">“They’ve survived one virus,” he said. “They don’t want to be nabbed by this one.”\u003c/p>\n\u003cp class=\"p1\">\u003cb>Lessons Learned From One Pandemic Help Save Lives in Another\u003c/b>\u003c/p>\n\u003cp class=\"p1\">John Schumacher, a 63-year-old soft spoken gay male, is a case in point. Over the years, the long-term HIV survivor and community volunteer has faced many perilous moments with his health.\u003cspan class=\"Apple-converted-space\"> \u003c/span>\u003c/p>\n\u003cp class=\"p1\">“I’ve learned to err on the side of caution,” Schumacher said. “You know, to wear a condom if someone else wants to, wear gloves, to do what is safer or what seems safe, even if I may not agree.”\u003c/p>\n\u003cp class=\"p1\">When the coronavirus started spreading, he started washing his hands diligently and wore a mask before it was widely recommended. He always carries hand sanitizer, and he says the same is true for his 31 housemates who are also HIV-positive. The group shares a community house in San Francisco. Fortunately no one has tested positive for COVID-19.\u003c/p>\n\u003cp class=\"p1\">“We think we had the training to do better in this pandemic,” said Jesus Guillen, of San Francisco. “We have experience at many of these things. We know how to push past barriers.”\u003c/p>\n\u003cp class=\"p1\">For example, even though Guillen loves to socialize, he didn’t balk when officials announced the stay-at-home directive because he understands all too well what’s at stake. Over the years, the tall flamboyant Latino has lost many close friends, including his first American lover whom he met soon after crossing the Mexican border in 1984.\u003c/p>\n\u003cfigure id=\"attachment_1966713\" class=\"wp-caption alignright\" style=\"max-width: 546px\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\" wp-image-1966713\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2020/07/PICT0293-800x600.jpg\" alt=\"Jesus Guillen snaps a selfie at Ocean Beach in San Francisco.\" width=\"546\" height=\"409\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/PICT0293-800x600.jpg 800w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/PICT0293-1020x765.jpg 1020w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/PICT0293-160x120.jpg 160w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/PICT0293-768x576.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/PICT0293-1536x1152.jpg 1536w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/PICT0293-2048x1536.jpg 2048w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/PICT0293-1920x1440.jpg 1920w\" sizes=\"(max-width: 546px) 100vw, 546px\">\u003cfigcaption class=\"wp-caption-text\">Jesus Guillen snaps a selfie at Ocean Beach in San Francisco. \u003ccite>(Jesus Guillen)\u003c/cite>\u003c/figcaption>\u003c/figure>\n\u003cp class=\"p3\">“I was with just one person,” he sighs. “And sadly, he died one year later.”\u003c/p>\n\u003cp class=\"p1\">\u003cb>‘We Got The Real Social Distancing’\u003c/b>\u003c/p>\n\u003cp class=\"p1\">Today, the 60-year-old with spiky platinum hair and a turquoise earring is a proud activist in San Francisco. But when he first found out he was HIV-positive, he was a shy immigrant who didn’t tell anyone.\u003c/p>\n\u003cp class=\"p1\">“In those times, they were not allowing people who were HIV-positive to stay in this country,” he said.\u003c/p>\n\u003cp class=\"p1\">But it was more than just fear of \u003ca href=\"https://www.americanbar.org/groups/crsj/publications/human_rights_magazine_home/human_rights_vol31_2004/fall2004/irr_hr_fall04_persecution/\">\u003cspan class=\"s3\">deportation\u003c/span>\u003c/a> that silenced Guillen. In 1985, a Los Angeles Times \u003ca href=\"https://www.latimes.com/archives/la-xpm-1985-12-19-mn-30337-story.html\">\u003cspan class=\"s3\">poll\u003c/span>\u003c/a> revealed a majority of Americans favored quarantining people with AIDS.\u003c/p>\n\u003cp class=\"p1\">“We got the social distancing through discrimination, through a stigma, through homophobia, through all those things, We got the real social distancing,” he said.\u003c/p>\n\u003cp class=\"p1\">At the beginning of the coronavirus outbreak, memories from the ’80s flooded back. The Grand Princess cruise ship carrying passengers with COVID-19 was docking at the Port of Oakland, when Guillen overheard a conversation on a bus.\u003c/p>\n\u003cp>“She was a normal average person saying, ‘Why do they allow them to be right there in Oakland? They should be taking these people to an island.'”\u003c/p>\n\u003cp class=\"p1\">“That took me back so much to the early ’80s with HIV.” Guillen winced. “People wanted to put us in cages or places completely separate.”\u003c/p>\n\u003cp class=\"p1\">\u003cb>Hauntingly Similar \u003c/b>\u003c/p>\n\u003cp class=\"p1\">Four decades ago, no one could have imagined AIDS would kill more than \u003ca href=\"https://www.kff.org/hivaids/fact-sheet/the-hivaids-epidemic-in-the-united-states-the-basics/\">\u003cspan class=\"s3\">700,000\u003c/span>\u003c/a> people in America, and more than \u003ca href=\"https://www.who.int/gho/hiv/en/\">\u003cspan class=\"s3\">32 million\u003c/span>\u003c/a> worldwide.\u003c/p>\n\u003cfigure id=\"attachment_1966715\" class=\"wp-caption alignright\" style=\"max-width: 721px\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\"wp-image-1966715 size-full\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2020/07/GettyImages-626934506-1-e1593659360168.jpg\" alt=\"Dr. Michael Gottlieb attends The Elizabeth Taylor AIDS Foundation World AIDS Day Event co-hosted by SAG-AFTRA at the at James Cagney Boardroom on November 30, 2016 in Los Angeles, California.\" width=\"721\" height=\"844\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-626934506-1-e1593659360168.jpg 721w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-626934506-1-e1593659360168-160x187.jpg 160w\" sizes=\"(max-width: 721px) 100vw, 721px\">\u003cfigcaption class=\"wp-caption-text\">Dr. Michael Gottlieb attends The Elizabeth Taylor AIDS Foundation World AIDS Day event co-hosted by SAG-AFTRA at the at James Cagney Boardroom on Nov. 30, 2016, in Los Angeles. \u003ccite>(Jesse Grant/Getty Images)\u003c/cite>\u003c/figcaption>\u003c/figure>\n\u003cp class=\"p1\">“I thought that the very first case might just be a one-off phenomenon,” said Dr. Michael Gottlieb, of UCLA. “We didn’t even know that AIDS was caused by a virus. We didn’t know that for two full years after the description of the first patients.”\u003c/p>\n\u003cp class=\"p1\">Scientists like Gottlieb struggled to access funding to study HIV. It took a couple of years before researchers understood how AIDS was transmitted. Fear plagued gay neighborhoods like the Castro. People worried a cough or a toilet seat might be a death sentence.\u003c/p>\n\u003cp class=\"p1\">“You’d go out in the street at night and no one would be there,” said Rick Solomon, a 65-year-old Berkeley resident who is enrolled in a COVID-19 study at San Francisco General. “And the bars were almost empty. People didn’t go out.”\u003c/p>\n\u003cp class=\"p1\">Throughout the ’80s, Solomon kept a little notebook of names of people who died. The list grew to more than 200 people. He was not surprised when he tested positive in 1990.\u003c/p>\n\u003cp class=\"p1\">Even though HIV and the new coronavirus are not similar in genome, transmission or mortality; the experience of living through two plagues is hauntingly comparable.\u003c/p>\n\u003cp class=\"p1\">“The apocalyptic scenes of New York City ICUs overwhelmed with people with COVID-19 pneumonia remind me of our early days where patients with AIDS presented very late with pneumocystis pneumonia and required ventilators,” said Gottlieb.\u003c/p>\n\u003cp class=\"p1\">Other elements are also familiar. Results from small studies are overblown. Officials change course abruptly. Public health is politicized. Lives become statistics. Headlines tout new cures. Vaccines are promised. And at the end of the day, individual actions save lives.\u003c/p>\n\u003cp class=\"p1\">“Back in the early ’80s, the answer was condoms and fewer sexual partners,” said Gottlieb. “Today, the answer is masks and social distancing. Behavior change is essential in preventing the spread of both of these viruses.”\u003c/p>\n\u003cfigure id=\"attachment_1966726\" class=\"wp-caption alignright\" style=\"max-width: 800px\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\"wp-image-1966726 size-medium\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2020/07/GettyImages-50861211-800x654.jpg\" alt=\"\" width=\"800\" height=\"654\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-50861211-800x654.jpg 800w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-50861211-1020x834.jpg 1020w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-50861211-160x131.jpg 160w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-50861211-768x628.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-50861211-1536x1256.jpg 1536w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-50861211-1920x1569.jpg 1920w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-50861211.jpg 2048w\" sizes=\"(max-width: 800px) 100vw, 800px\">\u003cfigcaption class=\"wp-caption-text\">ACT-UP protesters march through the streets surrounding the U.S. Capitol and shout “shame” outside the office of the Republican National Committee on May 20, 2004, in Washington, D.C. \u003ccite>(TIM SLOAN/AFP via Getty Images)\u003c/cite>\u003c/figcaption>\u003c/figure>\n\u003cp class=\"p1\">\u003cb>Piercing Differences\u003c/b>\u003c/p>\n\u003cp class=\"p1\">But, for many long-term HIV survivors, the differences between the two pandemics shadow the similarities.\u003c/p>\n\u003cp class=\"p1\">For years, HIV advocates and patients protested to garner government attention and funding. “We were literally fighting for our lives,” said Solomon.\u003c/p>\n\u003cp class=\"p1\">Today, many medical researchers say it’s difficult to find funding for projects that \u003cem>aren’t\u003c/em> coronavirus. Scientists mapped the entire COVID-19 genome and understood transmission within months, not years, after initial infections broke out in China.\u003c/p>\n\u003cp class=\"p1\">Now, a few months into the coronavirus outbreak, some people have hit the streets demanding officials do \u003ci>less\u003c/i> to protect society from the coronavirus.\u003c/p>\n\u003cp class=\"p1\">“In many ways, there’s no comparison,” says Guillen, “because in those days the reality is society in general didn’t care.”\u003c/p>\n\u003cp class=\"p1\">This week at the AIDS 2020 Conference, scientists may reveal a physiological reason HIV patients are weathering the coronavirus better than predicted. But, Guillen believes coping skills are playing a key role. Long-term survivors have pushed up against disinterest, oppression and even disgust for decades, and yet, “We found ways to keep going,” he said.\u003c/p>\n\u003cp>[ad floatright]\u003c/p>\n","blocks":[],"excerpt":"Even though HIV and the new coronavirus are not similar in genome, transmission or mortality; the experience of living through two plagues is hauntingly comparable.","status":"publish","parent":0,"modified":1704847213,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":3,"wordCount":1997},"headData":{"title":"For HIV Survivors, Pandemic Is Sad Reminder of Early Days of AIDS | KQED","description":"Even though HIV and the new coronavirus are not similar in genome, transmission or mortality; the experience of living through two plagues is hauntingly comparable.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":""},"source":"Coronavirus","audioUrl":"https://traffic.omny.fm/d/clips/0af137ef-751e-4b19-a055-aaef00d2d578/ffca7e9f-6831-41c5-bcaf-aaef00f5a073/dff3f868-1666-48e2-b665-abf0012761bc/audio.mp3","sticky":false,"templateType":"standard","featuredImageType":"standard","path":"/science/1966675/as-with-covid-19-uncertainty-and-stigma-marked-the-outbreak-of-hiv-now-these-men-navigate-a-new-pandemic","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp class=\"p1\">In January, two weeks after Rick Solomon joined the YMCA near his home, he fell ill. The 65-year-old Berkeley resident hoped to spend the month working out, instead he laid in bed wheezing, with crippling muscle aches. He missed several days of work at a small publishing house.\u003c/p>\n\u003cp class=\"p1\">\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"‘I am pretty sure that my patients, my older, primarily gay men who survived the ’80s and ’90s, were the first to effectively shelter in place because they know what a pandemic is.’","name":"pullquote","attributes":{"named":{"size":"medium","citation":"Dr. Steven Deeks, UCSF","label":""},"numeric":[]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>“I was sick for most of the month of February with a horrible cough like I’ve never had before,” said Solomon running his fingers through his thick salt and pepper hair. “It went into my chest. I used inhalers for the first time in my life.”\u003c/p>\n\u003cp class=\"p1\">He was never tested for COVID-19 because he hadn’t traveled overseas recently, which was one of the official requirements for testing at the time. And although he has since tested negative for the virus’ antibodies, Solomon still believes he may have caught the bug.\u003c/p>\n\u003cp class=\"p1\">“The test the lab used was not FDA approved,” he said. “So who knows? It was just a different kind of cold.”\u003c/p>\n\u003cp class=\"p1\">Solomon took the antibody test because he wanted to enroll in a study at Zuckerberg San Francisco General Hospital looking at HIV-positive people infected with COVID-19. It’s a topic of special interest to researchers.\u003c/p>\n\u003cp class=\"p1\">“COVID is going to have a major impact on the trajectory of the HIV epidemic,” said Dr. Steven Deeks, a UCSF professor of medicine and HIV researcher. “We just don’t know how.”\u003c/p>\n\u003cfigure id=\"attachment_1966721\" class=\"wp-caption alignright\" style=\"max-width: 527px\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\" wp-image-1966721\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2020/07/SD-ZSF-Photograph-800x534.jpg\" alt=\"Dr. Steven Deeks is a recognized expert on HIV-associated immune dysfunction and its impact on HIV persistence (the “reservoir”) and health during antiretroviral therapy. \" width=\"527\" height=\"351\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/SD-ZSF-Photograph-800x534.jpg 800w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/SD-ZSF-Photograph-1020x680.jpg 1020w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/SD-ZSF-Photograph-160x107.jpg 160w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/SD-ZSF-Photograph-768x512.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/SD-ZSF-Photograph-1536x1025.jpg 1536w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/SD-ZSF-Photograph-1920x1281.jpg 1920w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/SD-ZSF-Photograph.jpg 2048w\" sizes=\"(max-width: 527px) 100vw, 527px\">\u003cfigcaption class=\"wp-caption-text\">Dr. Steven Deeks is a recognized expert on HIV-associated immune dysfunction and its impact on HIV persistence (the “reservoir”) and health during antiretroviral therapy. \u003ccite>(UCSF)\u003c/cite>\u003c/figcaption>\u003c/figure>\n\u003cp class=\"p2\">Some answers may come to light this week at the \u003ca href=\"https://www.aids2020.org/\">\u003cspan class=\"s2\">23rd International AIDS Conference.\u003c/span>\u003c/a> The event was scheduled to happen in San Francisco and Oakland until the coronavirus hit. Now scientists, policymakers, public health experts and patients from around the world will gather virtually. COVID-19 is a central topic on the agenda.\u003c/p>\n\u003cp class=\"p1\">\u003cb>Surprising Positive Trend\u003c/b>\u003c/p>\n\u003cp class=\"p1\">Infectious disease doctors assumed people with HIV would be at higher risk for complications from the novel coronavirus due to a weakened immune system. Plus, the majority of HIV-positive people in the U.S. are older, and many struggle with underlying conditions like heart disease and diabetes, which make illness from COVID-19 infection more severe.\u003c/p>\n\u003cp class=\"p1\">Early in the outbreak, four of Dr. Edward “Lalo” Cachay’s patients were hospitalized for complications with COVID-19. Cachay, a professor of medicine at UC San Diego, feared the worst.\u003c/p>\n\u003cp class=\"p1\">“You could potentially have a very dangerous combination of both biological and social determinants of health,” said Cachay.\u003c/p>\n\u003cp class=\"p1\">HIV patients are not only immunocompromised, many also face psycho-social barriers like poor health insurance and mental illness. But not only did Cachay’s four patients experience good outcomes, this positive trend is playing out across the globe.\u003c/p>\n\u003cfigure id=\"attachment_1966724\" class=\"wp-caption alignright\" style=\"max-width: 438px\">\u003ca href=\"https://ww2.kqed.org/app/uploads/sites/35/2020/07/Cachay-Edward-_white-coat-2-e1593709402341.jpg\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\" wp-image-1966724\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2020/07/Cachay-Edward-_white-coat-2-e1593709402341-800x833.jpg\" alt=\"Edward “Lalo” Cachay, a professor of medicine at UCSD., smiles in a university portrait. He has warm brown eyes behind brown glasses and a closely trimmed, salt-and-pepper beard and mustache.\" width=\"438\" height=\"456\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/Cachay-Edward-_white-coat-2-e1593709402341-800x833.jpg 800w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/Cachay-Edward-_white-coat-2-e1593709402341-1020x1062.jpg 1020w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/Cachay-Edward-_white-coat-2-e1593709402341-160x167.jpg 160w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/Cachay-Edward-_white-coat-2-e1593709402341-768x800.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/Cachay-Edward-_white-coat-2-e1593709402341.jpg 1281w\" sizes=\"(max-width: 438px) 100vw, 438px\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Edward “Lalo” Cachay, a professor of medicine at UCSD. \u003ccite>(UCSD)\u003c/cite>\u003c/figcaption>\u003c/figure>\n\u003cp class=\"p1\">“People with HIV are radically underrepresented in the different cohorts coming from Europe and China with very advanced, severe forms of COVID-19,” Cachay said.\u003c/p>\n\u003cp class=\"p1\">Two small studies from \u003ca href=\"https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(20)30164-8/fulltext\">\u003cspan class=\"s1\">Spain\u003c/span>\u003c/a> and \u003ca href=\"https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(20)30164-8/fulltext\">\u003cspan class=\"s1\">Italy\u003c/span>\u003c/a> show that HIV-positive people infected with COVID-19 did not fare worse than those without HIV. Scientists are not sure why.\u003c/p>\n\u003cp class=\"p1\">\u003cb>More Questions Than Answers\u003c/b>\u003c/p>\n\u003cp class=\"p1\">“The bottom line is we have no idea,” said Deeks. “We have lots of interesting questions, lots of important questions, and lots of anecdotes. But at the end of day, we don’t have much data at all.”\u003c/p>\n\u003cp class=\"p1\">Cachay hopes a study he is involved in will offer concrete answers. He’s partnering with scientists at the Fred Hutchinson Cancer Research Center and the University of Washington to answer some key questions: \u003cspan class=\"s1\">What factors might predict which HIV patients are most at risk? Do HIV patients who contract COVID-19 suffer severe illness? And are mortality rates higher in HIV patients who contract the novel\u003c/span> \u003cspan class=\"s1\">coronavirus? \u003c/span>\u003c/p>\n\u003cp class=\"p2\">“I hope this study will help us disentangle the data more,” said Cachay.\u003c/p>\n\u003cp class=\"p1\">Some experts theorize daily HIV meds might offer some protection against the coronavirus. Others wonder if the immune system of people with HIV is altered in a way that offers some resilience. Or, perhaps, experience helps.\u003c/p>\n\u003cp class=\"p1\">“I am pretty sure that my patients, my older, primarily gay men who survived the ’80s and ’90s, were the first to effectively shelter in place because they know what a pandemic is,” said Deeks. “They know how a virus can ravage a community. They know how important social distancing is.”\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp class=\"p1\">Dr. Michael Gottlieb, the UCLA HIV physician who identified the first cluster of HIV cases in 1981, agrees.\u003c/p>\n\u003cp class=\"p1\">“They’ve survived one virus,” he said. “They don’t want to be nabbed by this one.”\u003c/p>\n\u003cp class=\"p1\">\u003cb>Lessons Learned From One Pandemic Help Save Lives in Another\u003c/b>\u003c/p>\n\u003cp class=\"p1\">John Schumacher, a 63-year-old soft spoken gay male, is a case in point. Over the years, the long-term HIV survivor and community volunteer has faced many perilous moments with his health.\u003cspan class=\"Apple-converted-space\"> \u003c/span>\u003c/p>\n\u003cp class=\"p1\">“I’ve learned to err on the side of caution,” Schumacher said. “You know, to wear a condom if someone else wants to, wear gloves, to do what is safer or what seems safe, even if I may not agree.”\u003c/p>\n\u003cp class=\"p1\">When the coronavirus started spreading, he started washing his hands diligently and wore a mask before it was widely recommended. He always carries hand sanitizer, and he says the same is true for his 31 housemates who are also HIV-positive. The group shares a community house in San Francisco. Fortunately no one has tested positive for COVID-19.\u003c/p>\n\u003cp class=\"p1\">“We think we had the training to do better in this pandemic,” said Jesus Guillen, of San Francisco. “We have experience at many of these things. We know how to push past barriers.”\u003c/p>\n\u003cp class=\"p1\">For example, even though Guillen loves to socialize, he didn’t balk when officials announced the stay-at-home directive because he understands all too well what’s at stake. Over the years, the tall flamboyant Latino has lost many close friends, including his first American lover whom he met soon after crossing the Mexican border in 1984.\u003c/p>\n\u003cfigure id=\"attachment_1966713\" class=\"wp-caption alignright\" style=\"max-width: 546px\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\" wp-image-1966713\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2020/07/PICT0293-800x600.jpg\" alt=\"Jesus Guillen snaps a selfie at Ocean Beach in San Francisco.\" width=\"546\" height=\"409\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/PICT0293-800x600.jpg 800w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/PICT0293-1020x765.jpg 1020w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/PICT0293-160x120.jpg 160w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/PICT0293-768x576.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/PICT0293-1536x1152.jpg 1536w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/PICT0293-2048x1536.jpg 2048w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/PICT0293-1920x1440.jpg 1920w\" sizes=\"(max-width: 546px) 100vw, 546px\">\u003cfigcaption class=\"wp-caption-text\">Jesus Guillen snaps a selfie at Ocean Beach in San Francisco. \u003ccite>(Jesus Guillen)\u003c/cite>\u003c/figcaption>\u003c/figure>\n\u003cp class=\"p3\">“I was with just one person,” he sighs. “And sadly, he died one year later.”\u003c/p>\n\u003cp class=\"p1\">\u003cb>‘We Got The Real Social Distancing’\u003c/b>\u003c/p>\n\u003cp class=\"p1\">Today, the 60-year-old with spiky platinum hair and a turquoise earring is a proud activist in San Francisco. But when he first found out he was HIV-positive, he was a shy immigrant who didn’t tell anyone.\u003c/p>\n\u003cp class=\"p1\">“In those times, they were not allowing people who were HIV-positive to stay in this country,” he said.\u003c/p>\n\u003cp class=\"p1\">But it was more than just fear of \u003ca href=\"https://www.americanbar.org/groups/crsj/publications/human_rights_magazine_home/human_rights_vol31_2004/fall2004/irr_hr_fall04_persecution/\">\u003cspan class=\"s3\">deportation\u003c/span>\u003c/a> that silenced Guillen. In 1985, a Los Angeles Times \u003ca href=\"https://www.latimes.com/archives/la-xpm-1985-12-19-mn-30337-story.html\">\u003cspan class=\"s3\">poll\u003c/span>\u003c/a> revealed a majority of Americans favored quarantining people with AIDS.\u003c/p>\n\u003cp class=\"p1\">“We got the social distancing through discrimination, through a stigma, through homophobia, through all those things, We got the real social distancing,” he said.\u003c/p>\n\u003cp class=\"p1\">At the beginning of the coronavirus outbreak, memories from the ’80s flooded back. The Grand Princess cruise ship carrying passengers with COVID-19 was docking at the Port of Oakland, when Guillen overheard a conversation on a bus.\u003c/p>\n\u003cp>“She was a normal average person saying, ‘Why do they allow them to be right there in Oakland? They should be taking these people to an island.'”\u003c/p>\n\u003cp class=\"p1\">“That took me back so much to the early ’80s with HIV.” Guillen winced. “People wanted to put us in cages or places completely separate.”\u003c/p>\n\u003cp class=\"p1\">\u003cb>Hauntingly Similar \u003c/b>\u003c/p>\n\u003cp class=\"p1\">Four decades ago, no one could have imagined AIDS would kill more than \u003ca href=\"https://www.kff.org/hivaids/fact-sheet/the-hivaids-epidemic-in-the-united-states-the-basics/\">\u003cspan class=\"s3\">700,000\u003c/span>\u003c/a> people in America, and more than \u003ca href=\"https://www.who.int/gho/hiv/en/\">\u003cspan class=\"s3\">32 million\u003c/span>\u003c/a> worldwide.\u003c/p>\n\u003cfigure id=\"attachment_1966715\" class=\"wp-caption alignright\" style=\"max-width: 721px\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\"wp-image-1966715 size-full\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2020/07/GettyImages-626934506-1-e1593659360168.jpg\" alt=\"Dr. Michael Gottlieb attends The Elizabeth Taylor AIDS Foundation World AIDS Day Event co-hosted by SAG-AFTRA at the at James Cagney Boardroom on November 30, 2016 in Los Angeles, California.\" width=\"721\" height=\"844\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-626934506-1-e1593659360168.jpg 721w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-626934506-1-e1593659360168-160x187.jpg 160w\" sizes=\"(max-width: 721px) 100vw, 721px\">\u003cfigcaption class=\"wp-caption-text\">Dr. Michael Gottlieb attends The Elizabeth Taylor AIDS Foundation World AIDS Day event co-hosted by SAG-AFTRA at the at James Cagney Boardroom on Nov. 30, 2016, in Los Angeles. \u003ccite>(Jesse Grant/Getty Images)\u003c/cite>\u003c/figcaption>\u003c/figure>\n\u003cp class=\"p1\">“I thought that the very first case might just be a one-off phenomenon,” said Dr. Michael Gottlieb, of UCLA. “We didn’t even know that AIDS was caused by a virus. We didn’t know that for two full years after the description of the first patients.”\u003c/p>\n\u003cp class=\"p1\">Scientists like Gottlieb struggled to access funding to study HIV. It took a couple of years before researchers understood how AIDS was transmitted. Fear plagued gay neighborhoods like the Castro. People worried a cough or a toilet seat might be a death sentence.\u003c/p>\n\u003cp class=\"p1\">“You’d go out in the street at night and no one would be there,” said Rick Solomon, a 65-year-old Berkeley resident who is enrolled in a COVID-19 study at San Francisco General. “And the bars were almost empty. People didn’t go out.”\u003c/p>\n\u003cp class=\"p1\">Throughout the ’80s, Solomon kept a little notebook of names of people who died. The list grew to more than 200 people. He was not surprised when he tested positive in 1990.\u003c/p>\n\u003cp class=\"p1\">Even though HIV and the new coronavirus are not similar in genome, transmission or mortality; the experience of living through two plagues is hauntingly comparable.\u003c/p>\n\u003cp class=\"p1\">“The apocalyptic scenes of New York City ICUs overwhelmed with people with COVID-19 pneumonia remind me of our early days where patients with AIDS presented very late with pneumocystis pneumonia and required ventilators,” said Gottlieb.\u003c/p>\n\u003cp class=\"p1\">Other elements are also familiar. Results from small studies are overblown. Officials change course abruptly. Public health is politicized. Lives become statistics. Headlines tout new cures. Vaccines are promised. And at the end of the day, individual actions save lives.\u003c/p>\n\u003cp class=\"p1\">“Back in the early ’80s, the answer was condoms and fewer sexual partners,” said Gottlieb. “Today, the answer is masks and social distancing. Behavior change is essential in preventing the spread of both of these viruses.”\u003c/p>\n\u003cfigure id=\"attachment_1966726\" class=\"wp-caption alignright\" style=\"max-width: 800px\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\"wp-image-1966726 size-medium\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2020/07/GettyImages-50861211-800x654.jpg\" alt=\"\" width=\"800\" height=\"654\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-50861211-800x654.jpg 800w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-50861211-1020x834.jpg 1020w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-50861211-160x131.jpg 160w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-50861211-768x628.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-50861211-1536x1256.jpg 1536w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-50861211-1920x1569.jpg 1920w, https://cdn.kqed.org/wp-content/uploads/sites/35/2020/07/GettyImages-50861211.jpg 2048w\" sizes=\"(max-width: 800px) 100vw, 800px\">\u003cfigcaption class=\"wp-caption-text\">ACT-UP protesters march through the streets surrounding the U.S. Capitol and shout “shame” outside the office of the Republican National Committee on May 20, 2004, in Washington, D.C. \u003ccite>(TIM SLOAN/AFP via Getty Images)\u003c/cite>\u003c/figcaption>\u003c/figure>\n\u003cp class=\"p1\">\u003cb>Piercing Differences\u003c/b>\u003c/p>\n\u003cp class=\"p1\">But, for many long-term HIV survivors, the differences between the two pandemics shadow the similarities.\u003c/p>\n\u003cp class=\"p1\">For years, HIV advocates and patients protested to garner government attention and funding. “We were literally fighting for our lives,” said Solomon.\u003c/p>\n\u003cp class=\"p1\">Today, many medical researchers say it’s difficult to find funding for projects that \u003cem>aren’t\u003c/em> coronavirus. Scientists mapped the entire COVID-19 genome and understood transmission within months, not years, after initial infections broke out in China.\u003c/p>\n\u003cp class=\"p1\">Now, a few months into the coronavirus outbreak, some people have hit the streets demanding officials do \u003ci>less\u003c/i> to protect society from the coronavirus.\u003c/p>\n\u003cp class=\"p1\">“In many ways, there’s no comparison,” says Guillen, “because in those days the reality is society in general didn’t care.”\u003c/p>\n\u003cp class=\"p1\">This week at the AIDS 2020 Conference, scientists may reveal a physiological reason HIV patients are weathering the coronavirus better than predicted. But, Guillen believes coping skills are playing a key role. Long-term survivors have pushed up against disinterest, oppression and even disgust for decades, and yet, “We found ways to keep going,” he said.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"floatright"},"numeric":["floatright"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/science/1966675/as-with-covid-19-uncertainty-and-stigma-marked-the-outbreak-of-hiv-now-these-men-navigate-a-new-pandemic","authors":["11229"],"categories":["science_39","science_4550","science_3890","science_40","science_4450"],"tags":["science_4329","science_4417","science_4414","science_5181","science_660"],"featImg":"science_1966686","label":"source_science_1966675"},"science_1952464":{"type":"posts","id":"science_1952464","meta":{"index":"posts_1591205157","site":"science","id":"1952464","score":null,"sort":[1577109604000]},"guestAuthors":[],"slug":"the-big-science-and-environment-stories-of-the-decade","title":"The Big Science and Environment Stories of the Decade","publishDate":1577109604,"format":"standard","headTitle":"The Big Science and Environment Stories of the Decade | KQED","labelTerm":{},"content":"\u003cp>The 2010s saw breakthroughs in medical science and spectacular discoveries in space and physics. For Californians, it was also the decade that climate change arrived in our front yards in the form of serial cataclysmic fire seasons.\u003c/p>\n\u003cp>During the decade, scientists refined the regimen of HIV/AIDS medication, made life-saving advances in the treatment of cancer, and invented an entirely new gene-editing technology, with the hope of one day curing diseases before they begin.\u003c/p>\n\u003cp>NASA’s New Horizons probe captured the first close-up \u003ca href=\"https://www.nasa.gov/feature/new-horizons-best-close-up-of-plutos-surface\" target=\"_blank\" rel=\"noopener noreferrer\">images\u003c/a> \u003ca href=\"https://www.nasa.gov/feature/new-horizons-best-close-up-of-plutos-surface\">of\u003c/a> \u003ca href=\"https://www.nasa.gov/feature/new-horizons-best-close-up-of-plutos-surface\">Pluto\u003c/a>, and the world caught its first \u003ca href=\"https://www.kqed.org/forum/2010101870482/first-photos-of-a-black-hole-captured-by-event-horizon-telescope-project\" target=\"_blank\" rel=\"noopener noreferrer\">glimpse\u003c/a>, albeit a bit blurry, of a black hole. Our understanding of exoplanets exploded: the Kepler Space Telescope and the TESS satellite found thousands of new planets outside our solar system, and researchers began to comprehend what those worlds might actually look like.\u003c/p>\n\u003cp>As the decade closes, the KQED Science team has created a sort of mixtape of the major trends, significant moments and noteworthy discoveries, with an eye toward California and the Bay Area.\u003c/p>\n\u003cp>Do you want the good news or the bad news first? Well, let’s get it out of the way …\u003c/p>\n\u003cp>\u003cstrong>Wildfires Create Havoc\u003c/strong>\u003c/p>\n\u003cfigure id=\"attachment_1952558\" class=\"wp-caption alignright\" style=\"max-width: 640px\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\"wp-image-1952558 size-complete_open_graph\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2019/12/RS40592_GettyImages-1178415177-qut-1200x800.jpg\" alt=\"\" width=\"640\" height=\"427\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40592_GettyImages-1178415177-qut-1200x800.jpg 1200w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40592_GettyImages-1178415177-qut-160x107.jpg 160w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40592_GettyImages-1178415177-qut-800x533.jpg 800w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40592_GettyImages-1178415177-qut-768x512.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40592_GettyImages-1178415177-qut-1020x680.jpg 1020w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40592_GettyImages-1178415177-qut.jpg 1920w\" sizes=\"(max-width: 640px) 100vw, 640px\">\u003cfigcaption class=\"wp-caption-text\">A crew of inmate firefighters make their way to firefighting operations to battle the Kincade Fire in Healdsburg, California on October 26, 2019.\u003c/figcaption>\u003c/figure>\n\u003cp>The changing climate is leading to longer dry periods in California, which is at least three degrees warmer since the beginning of the industrial era, the Environmental Protection Agency \u003ca href=\"https://www.epa.gov/sites/production/files/2016-09/documents/climate-change-ca.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">reported\u003c/a> in 2016.\u003c/p>\n\u003cp>Climate change, combined with a century of suppressing wildfires and denser populations in areas perilously close to fire-prone wilderness, have created the worst fire seasons on record. Since 2012, four of the five \u003ca href=\"https://www.fire.ca.gov/media/5510/top20_acres.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">biggest\u003c/a> California wildfires have \u003ca href=\"https://www.kqed.org/science/1934533/the-new-abnormal-climate-effects-on-the-fire-season-are-just-beginning;%20https:/www.kqed.org/science/1950703/climate-change-is-driving-californias-wildfires-the-kincade-fire-not-so-much)\" target=\"_blank\" rel=\"noopener noreferrer\">burned\u003c/a> over 1.2 million acres.\u003c/p>\n\u003cp>Late on Oct. 8, 2017, hot, dry winds downed power lines, carrying sparks and flaming embers long distances to ignite multiple fires. The Tubbs Fire and other North Bay blazes scorched large areas of Sonoma and Napa counties, claiming 44 lives and destroying over 8,000 buildings.\u003c/p>\n\u003cp>The following summer, during the Carr Fire, a “\u003ca href=\"https://www.kqed.org/science/1928143/reddings-firenado-was-not-your-garden-variety-fire-whirl\" target=\"_blank\" rel=\"noopener noreferrer\">fire tornado\u003c/a>” exploded into the outskirts of Redding, devastating everything in its path. The blaze killed eight people and destroyed 1,000 homes.\u003c/p>\n\u003cp>But the worst was yet to come. In November, the Camp Fire nearly wiped out the town of Paradise and surrounding communities. It was the deadliest wildfire in California history, killing 86 people, destroying almost 14,000 homes, and costing more money than any natural disaster in the world that year. Across wide swaths of the state, smoke from the fire rendered the air unhealthy to breathe, inundating the Bay Area for almost two weeks so that the region registered its worst air quality on record.\u003c/p>\n\u003cfigure id=\"attachment_1952579\" class=\"wp-caption alignleft\" style=\"max-width: 640px\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\"wp-image-1952579 size-complete_open_graph\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2019/12/RS40593_GettyImages-1129061413-qut-1200x774.jpg\" alt=\"\" width=\"640\" height=\"413\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40593_GettyImages-1129061413-qut-1200x774.jpg 1200w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40593_GettyImages-1129061413-qut-160x103.jpg 160w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40593_GettyImages-1129061413-qut-800x516.jpg 800w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40593_GettyImages-1129061413-qut-768x495.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40593_GettyImages-1129061413-qut-1020x658.jpg 1020w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40593_GettyImages-1129061413-qut.jpg 1920w\" sizes=\"(max-width: 640px) 100vw, 640px\">\u003cfigcaption class=\"wp-caption-text\">An aerial view of homes destroyed by the Camp Fire on February 11, 2019 in Paradise, California. \u003ccite>(Photo by Justin Sullivan/Getty Images)\u003c/cite>\u003c/figcaption>\u003c/figure>\n\u003cp>As far as global warming goes, the outlook is not good, whether it relates to fires or to other natural disasters. The 2010s included the hottest year (2017) and the hottest month (July 2019) on record, and the 10 years that make up the decade will almost certainly set a new temperature mark as well, according to the U.N., based on millions of global measurements taken over the last 170 years.\u003c/p>\n\u003cp>This summer, our series \u003ca href=\"https://www.kqed.org/science/tag/livingwithwildfire\" target=\"_blank\" rel=\"noopener noreferrer\">Living With Wildfire: California Reimagined\u003c/a> asked some big questions about how the state can, in our warming world, learn to survive more frequent and ferocious conflagrations. Are some fire-prone areas now too dangerous to accommodate new housing? How can towns prepare for mass evacuations? And neighborhoods make themselves fire-resistant? Are Californians willing to suffer the inconvenience and financial cost to protect the state from extreme wildfires? Perhaps, but it will mean big changes in how we think and live. — \u003ca href=\"https://twitter.com/DanielleVenton\" target=\"_blank\" rel=\"noopener noreferrer\">Danielle Venton\u003c/a>\u003c/p>\n\u003cp>\u003cstrong>Rise of Renewables\u003c/strong>\u003c/p>\n\u003cp>As Californians began to experience climate change in the form of hotter days and more destructive fires, state policies to mitigate global warming began to pay dividends. California’s investor-owned utilities shattered \u003ca href=\"https://www.cpuc.ca.gov/rps/\" target=\"_blank\" rel=\"noopener noreferrer\">renewable energy\u003c/a> targets mandated by the state, and California \u003ca href=\"https://apnews.com/942b5a251fac413a84fc4eb93a67c46c/California-meets-greenhouse-gas-reduction-goal-years-early\">reduced\u003c/a> its overall emissions of greenhouse gases below the 1990 level, two years ahead of schedule.\u003c/p>\n\u003cp>These climate policies, in a state with the world’s fifth largest economy, helped spur a rapid decline in the cost of renewable energy around the U.S. This past decade, the cost of wind energy fell by 57%, utility-scale solar power by 86%, and battery energy storage by 76%. In 2019, for the first time, power generation in the U.S. from renewable energy \u003ca href=\"https://www.eia.gov/todayinenergy/detail.php?id=39992\" target=\"_blank\" rel=\"noopener noreferrer\">surpassed\u003c/a> power produced from coal. \u003cimg loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-1952593 alignright\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2019/12/2019Batteries_Cost_CMN-768x564-1.jpg\" alt=\"\" width=\"768\" height=\"564\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/2019Batteries_Cost_CMN-768x564-1.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/2019Batteries_Cost_CMN-768x564-1-160x118.jpg 160w\" sizes=\"(max-width: 768px) 100vw, 768px\">\u003c/p>\n\u003cp>Those are big successes, but California has a lot of work to do over the next 10 years if the state is going to meet its 2045 goal of net-zero emissions, also called carbon neutrality. California is \u003ca href=\"https://www.kqed.org/science/1948712/your-suv-is-really-messing-with-the-states-climate-plans\" target=\"_blank\" rel=\"noopener noreferrer\">way behind \u003c/a>in meeting this ambitious objective, in part because emissions from the transportation sector are soaring, due to Californians driving more miles in larger, gas-guzzling trucks and of SUVs.\u003c/p>\n\u003cp>The state is trying to reverse this trend by incentivizing fuel-efficient cars and setting a \u003ca href=\"https://www.cpuc.ca.gov/zev/\" target=\"_blank\" rel=\"noopener noreferrer\">target\u003c/a> of 5 million electric vehicles traversing California roads by 2030. But meeting that goal is going to be tough, with sales of EVs currently standing at only a \u003ca href=\"https://www.veloz.org/sales-dashboard/\" target=\"_blank\" rel=\"noopener noreferrer\">fraction of that total.\u003c/a>\u003c/p>\n\u003cp>Meanwhile, frustrated by the lack of progress in the fight against climate change, young people took to the streets the last couple of years. The Sunrise Movement, Youth vs. Apocalypse and other Bay Area advocacy groups participated in \u003ca href=\"https://www.kqed.org/science/1947584/live-blog-bay-area-climate-strike\" target=\"_blank\" rel=\"noopener noreferrer\">global climate strikes \u003c/a>protesting the failure of government, finance, industry and other institutions to address climate change.– \u003ca href=\"https://twitter.com/StarkKev\" target=\"_blank\" rel=\"noopener noreferrer\">Kevin Stark\u003c/a>\u003c/p>\n\u003cp>\u003cstrong>Medical Advances\u003c/strong>\u003c/p>\n\u003cp>The decade saw major advances in the treatment of HIV and cancer.\u003c/p>\n\u003cp>Over the last 10 years, scientists have perfected antiretroviral drugs, taken daily in a single pill by people who are HIV-positive. These drugs allow HIV patients to live relatively free of sickness, a far cry from the first decade of the epidemic, when the diagnosis was tantamount to a death sentence. No longer highly toxic, antiretrovirals now work so well they can lower a patient’s viral load to undetectable levels, making it untransmittable from one person to another. Another daily pill, called \u003ca href=\"https://www.sfaf.org/resource-library/prep/?utm_source=GoogleAds&utm_medium=CPC&utm_campaign=GoogleAds_UEqualsU_PrEP&gclid=CjwKCAiAluLvBRASEiwAAbX3GcnQ19OOhwWeCw4YFui4HMm-wM45wQzXB0fgh9a1hPAxzgkFYKnxRBoCsswQAvD_BwE\" target=\"_blank\" rel=\"noopener noreferrer\">PrEP,\u003c/a> can be used as a prophylactic against HIV exposure by people who are still free of the virus. Such major strides in treatment and prevention are why scientists are optimistic HIV will be eradicated altogether within the next decade.\u003c/p>\n\u003cp>For some types of cancer, a treatment called immunotherapy drastically improved survival and cure rates. For example, \u003ca href=\"https://www.kqed.org/futureofyou/444527/advanced-skin-cancer-was-once-a-death-sentence-immunotherapy-is-changing-that\" target=\"_blank\" rel=\"noopener noreferrer\">stage 4 melanoma \u003c/a>, which doesn’t respond to radiation or chemotherapy, used to mean \u003ca href=\"https://www.kqed.org/futureofyou/444527/advanced-skin-cancer-was-once-a-death-sentence-immunotherapy-is-changing-that\" target=\"_blank\" rel=\"noopener noreferrer\">certain death\u003c/a>, with patients surviving less than a year on average. But over the last decade, instead of burning or poisoning cancer cells to stop the disease, new medicines have unleashed the body’s natural defenses.\u003c/p>\n\u003cp>Normally the immune system recognizes disease-causing organisms. But cancer cells go undetected as harmful. New drugs, as well as \u003ca href=\"https://www.kqed.org/futureofyou/439584/new-gene-therapy-gives-teen-a-second-chance-after-cancer\" target=\"_blank\" rel=\"noopener noreferrer\">genetic engineering\u003c/a> techniques, make them visible and ripe for attack. Think of it like affixing a flag with the message “kill me” on cells that previously operated with impunity. Pancreatic, breast and prostate cancer, among other types, do not currently respond to immunotherapy, but scientists foresee a day when the treatment could be the primary weapon against an array of cancers.\u003c/p>\n\u003cp>\u003ca href=\"https://ww2.kqed.org/app/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1.jpg\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1952602 size-complete_open_graph\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1-1200x797.jpg\" alt=\"\" width=\"640\" height=\"425\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1-1200x797.jpg 1200w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1-160x106.jpg 160w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1-800x531.jpg 800w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1-768x510.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1-1020x677.jpg 1020w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1.jpg 1280w\" sizes=\"(max-width: 640px) 100vw, 640px\">\u003c/a>\u003c/p>\n\u003cp>There may also be a day when doctors can eliminate genetic diseases altogether. A tool called \u003ca href=\"https://www.kqed.org/futureofyou/370/a-crispr-solution-to-bubble-boy-disease\" target=\"_blank\" rel=\"noopener noreferrer\">CRISPR \u003c/a>acts as a molecular scalpel that can make precise changes to genetic mutations giving rise to disease. Scientists hope to one day cure genetic conditions like blindness or sickle cell anemia before they even start. Though tinkering with our DNA raises all kinds of ethical questions about “\u003ca href=\"https://www.kqed.org/science/1934916/chinese-scientist-says-hes-first-to-create-genetically-modified-babies-using-crispr\" target=\"_blank\" rel=\"noopener noreferrer\">playing God\u003c/a>.”– \u003ca href=\"https://twitter.com/lesleywmcclurg\" target=\"_blank\" rel=\"noopener noreferrer\">Lesley McClurg\u003c/a>\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>\u003cstrong>Predictions Fulfilled\u003c/strong>\u003c/p>\n\u003cp>The decade saw some spectacular discoveries in space and physics, some of which had been predicted for decades. Theoretical foresight frequently falls short or remains unproven, but once in a while, it’s right on the money.\u003c/p>\n\u003cp>Two discoveries in particular should be remembered as a vindication of the human ability to understand and model the world.\u003c/p>\n\u003cp>In 2012, two teams at CERN, often referred to as the European Laboratory for Particle Physics, announced they had independently detected the Higgs boson. This is a particle associated with an energy field, called the Higgs field, that was theorized in the 1960s and ’70s as a solution to the question: How does matter obtain mass?\u003c/p>\n\u003cp>The answer: Through the action of an elementary particle, such as an electron or a quark, interacting with the Higgs field. The more the particle interacts, the more massive it is. And the boson? That’s the particle that the Higgs field emits. The detection of the Higgs boson proved that the Higgs field is real, and it was the final piece of the puzzle for the Standard Model, a set of equations describing how three of the four fundamental forces work. Now, only gravity remains unexplained.\u003c/p>\n\u003cp>The decade also saw the discovery of gravitational waves, predicted by none other than Albert Einstein in 1916. Einstein thought the acceleration of objects with enough mass would create ripples in the fabric of spacetime. And he thought right. About 100 years later, dual detectors that make up the Laser Interferometer Gravitational-Wave Observatory, or LIGO, registered those ripples in the form of the aftershock created by two black holes colliding.\u003c/p>\n\u003cp>Traveling far above Earth-bound detection instruments like LIGO, spacecraft originating on Earth reached interstellar space for the first time. These are the Voyager probes, each carrying a copy of the \u003ca href=\"https://voyager.jpl.nasa.gov/golden-record/\" target=\"_blank\" rel=\"noopener noreferrer\">Golden Record\u003c/a>, which holds images, music and greetings from Earth. — \u003ca href=\"https://twitter.com/DanielleVenton\" target=\"_blank\" rel=\"noopener noreferrer\">Danielle Venton\u003c/a>\u003c/p>\n\u003cp>[ad floatright]\u003c/p>\n","blocks":[],"excerpt":"Developments and discoveries with the biggest impact, as curated by the KQED Science team.","status":"publish","parent":0,"modified":1704847972,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":35,"wordCount":1647},"headData":{"title":"The Big Science and Environment Stories of the Decade | KQED","description":"Developments and discoveries with the biggest impact, as curated by the KQED Science team.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":""},"source":"Discoveries and Trends","audioUrl":"https://www.kqed.org/.stream/anon/radio/science/2019/12/ScienceDecadeRoundtable.mp3","sticky":false,"audioTrackLength":441,"path":"/science/1952464/the-big-science-and-environment-stories-of-the-decade","parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>The 2010s saw breakthroughs in medical science and spectacular discoveries in space and physics. For Californians, it was also the decade that climate change arrived in our front yards in the form of serial cataclysmic fire seasons.\u003c/p>\n\u003cp>During the decade, scientists refined the regimen of HIV/AIDS medication, made life-saving advances in the treatment of cancer, and invented an entirely new gene-editing technology, with the hope of one day curing diseases before they begin.\u003c/p>\n\u003cp>NASA’s New Horizons probe captured the first close-up \u003ca href=\"https://www.nasa.gov/feature/new-horizons-best-close-up-of-plutos-surface\" target=\"_blank\" rel=\"noopener noreferrer\">images\u003c/a> \u003ca href=\"https://www.nasa.gov/feature/new-horizons-best-close-up-of-plutos-surface\">of\u003c/a> \u003ca href=\"https://www.nasa.gov/feature/new-horizons-best-close-up-of-plutos-surface\">Pluto\u003c/a>, and the world caught its first \u003ca href=\"https://www.kqed.org/forum/2010101870482/first-photos-of-a-black-hole-captured-by-event-horizon-telescope-project\" target=\"_blank\" rel=\"noopener noreferrer\">glimpse\u003c/a>, albeit a bit blurry, of a black hole. Our understanding of exoplanets exploded: the Kepler Space Telescope and the TESS satellite found thousands of new planets outside our solar system, and researchers began to comprehend what those worlds might actually look like.\u003c/p>\n\u003cp>As the decade closes, the KQED Science team has created a sort of mixtape of the major trends, significant moments and noteworthy discoveries, with an eye toward California and the Bay Area.\u003c/p>\n\u003cp>Do you want the good news or the bad news first? Well, let’s get it out of the way …\u003c/p>\n\u003cp>\u003cstrong>Wildfires Create Havoc\u003c/strong>\u003c/p>\n\u003cfigure id=\"attachment_1952558\" class=\"wp-caption alignright\" style=\"max-width: 640px\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\"wp-image-1952558 size-complete_open_graph\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2019/12/RS40592_GettyImages-1178415177-qut-1200x800.jpg\" alt=\"\" width=\"640\" height=\"427\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40592_GettyImages-1178415177-qut-1200x800.jpg 1200w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40592_GettyImages-1178415177-qut-160x107.jpg 160w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40592_GettyImages-1178415177-qut-800x533.jpg 800w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40592_GettyImages-1178415177-qut-768x512.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40592_GettyImages-1178415177-qut-1020x680.jpg 1020w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40592_GettyImages-1178415177-qut.jpg 1920w\" sizes=\"(max-width: 640px) 100vw, 640px\">\u003cfigcaption class=\"wp-caption-text\">A crew of inmate firefighters make their way to firefighting operations to battle the Kincade Fire in Healdsburg, California on October 26, 2019.\u003c/figcaption>\u003c/figure>\n\u003cp>The changing climate is leading to longer dry periods in California, which is at least three degrees warmer since the beginning of the industrial era, the Environmental Protection Agency \u003ca href=\"https://www.epa.gov/sites/production/files/2016-09/documents/climate-change-ca.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">reported\u003c/a> in 2016.\u003c/p>\n\u003cp>Climate change, combined with a century of suppressing wildfires and denser populations in areas perilously close to fire-prone wilderness, have created the worst fire seasons on record. Since 2012, four of the five \u003ca href=\"https://www.fire.ca.gov/media/5510/top20_acres.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">biggest\u003c/a> California wildfires have \u003ca href=\"https://www.kqed.org/science/1934533/the-new-abnormal-climate-effects-on-the-fire-season-are-just-beginning;%20https:/www.kqed.org/science/1950703/climate-change-is-driving-californias-wildfires-the-kincade-fire-not-so-much)\" target=\"_blank\" rel=\"noopener noreferrer\">burned\u003c/a> over 1.2 million acres.\u003c/p>\n\u003cp>Late on Oct. 8, 2017, hot, dry winds downed power lines, carrying sparks and flaming embers long distances to ignite multiple fires. The Tubbs Fire and other North Bay blazes scorched large areas of Sonoma and Napa counties, claiming 44 lives and destroying over 8,000 buildings.\u003c/p>\n\u003cp>The following summer, during the Carr Fire, a “\u003ca href=\"https://www.kqed.org/science/1928143/reddings-firenado-was-not-your-garden-variety-fire-whirl\" target=\"_blank\" rel=\"noopener noreferrer\">fire tornado\u003c/a>” exploded into the outskirts of Redding, devastating everything in its path. The blaze killed eight people and destroyed 1,000 homes.\u003c/p>\n\u003cp>But the worst was yet to come. In November, the Camp Fire nearly wiped out the town of Paradise and surrounding communities. It was the deadliest wildfire in California history, killing 86 people, destroying almost 14,000 homes, and costing more money than any natural disaster in the world that year. Across wide swaths of the state, smoke from the fire rendered the air unhealthy to breathe, inundating the Bay Area for almost two weeks so that the region registered its worst air quality on record.\u003c/p>\n\u003cfigure id=\"attachment_1952579\" class=\"wp-caption alignleft\" style=\"max-width: 640px\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\"wp-image-1952579 size-complete_open_graph\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2019/12/RS40593_GettyImages-1129061413-qut-1200x774.jpg\" alt=\"\" width=\"640\" height=\"413\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40593_GettyImages-1129061413-qut-1200x774.jpg 1200w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40593_GettyImages-1129061413-qut-160x103.jpg 160w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40593_GettyImages-1129061413-qut-800x516.jpg 800w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40593_GettyImages-1129061413-qut-768x495.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40593_GettyImages-1129061413-qut-1020x658.jpg 1020w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/RS40593_GettyImages-1129061413-qut.jpg 1920w\" sizes=\"(max-width: 640px) 100vw, 640px\">\u003cfigcaption class=\"wp-caption-text\">An aerial view of homes destroyed by the Camp Fire on February 11, 2019 in Paradise, California. \u003ccite>(Photo by Justin Sullivan/Getty Images)\u003c/cite>\u003c/figcaption>\u003c/figure>\n\u003cp>As far as global warming goes, the outlook is not good, whether it relates to fires or to other natural disasters. The 2010s included the hottest year (2017) and the hottest month (July 2019) on record, and the 10 years that make up the decade will almost certainly set a new temperature mark as well, according to the U.N., based on millions of global measurements taken over the last 170 years.\u003c/p>\n\u003cp>This summer, our series \u003ca href=\"https://www.kqed.org/science/tag/livingwithwildfire\" target=\"_blank\" rel=\"noopener noreferrer\">Living With Wildfire: California Reimagined\u003c/a> asked some big questions about how the state can, in our warming world, learn to survive more frequent and ferocious conflagrations. Are some fire-prone areas now too dangerous to accommodate new housing? How can towns prepare for mass evacuations? And neighborhoods make themselves fire-resistant? Are Californians willing to suffer the inconvenience and financial cost to protect the state from extreme wildfires? Perhaps, but it will mean big changes in how we think and live. — \u003ca href=\"https://twitter.com/DanielleVenton\" target=\"_blank\" rel=\"noopener noreferrer\">Danielle Venton\u003c/a>\u003c/p>\n\u003cp>\u003cstrong>Rise of Renewables\u003c/strong>\u003c/p>\n\u003cp>As Californians began to experience climate change in the form of hotter days and more destructive fires, state policies to mitigate global warming began to pay dividends. California’s investor-owned utilities shattered \u003ca href=\"https://www.cpuc.ca.gov/rps/\" target=\"_blank\" rel=\"noopener noreferrer\">renewable energy\u003c/a> targets mandated by the state, and California \u003ca href=\"https://apnews.com/942b5a251fac413a84fc4eb93a67c46c/California-meets-greenhouse-gas-reduction-goal-years-early\">reduced\u003c/a> its overall emissions of greenhouse gases below the 1990 level, two years ahead of schedule.\u003c/p>\n\u003cp>These climate policies, in a state with the world’s fifth largest economy, helped spur a rapid decline in the cost of renewable energy around the U.S. This past decade, the cost of wind energy fell by 57%, utility-scale solar power by 86%, and battery energy storage by 76%. In 2019, for the first time, power generation in the U.S. from renewable energy \u003ca href=\"https://www.eia.gov/todayinenergy/detail.php?id=39992\" target=\"_blank\" rel=\"noopener noreferrer\">surpassed\u003c/a> power produced from coal. \u003cimg loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-1952593 alignright\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2019/12/2019Batteries_Cost_CMN-768x564-1.jpg\" alt=\"\" width=\"768\" height=\"564\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/2019Batteries_Cost_CMN-768x564-1.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/2019Batteries_Cost_CMN-768x564-1-160x118.jpg 160w\" sizes=\"(max-width: 768px) 100vw, 768px\">\u003c/p>\n\u003cp>Those are big successes, but California has a lot of work to do over the next 10 years if the state is going to meet its 2045 goal of net-zero emissions, also called carbon neutrality. California is \u003ca href=\"https://www.kqed.org/science/1948712/your-suv-is-really-messing-with-the-states-climate-plans\" target=\"_blank\" rel=\"noopener noreferrer\">way behind \u003c/a>in meeting this ambitious objective, in part because emissions from the transportation sector are soaring, due to Californians driving more miles in larger, gas-guzzling trucks and of SUVs.\u003c/p>\n\u003cp>The state is trying to reverse this trend by incentivizing fuel-efficient cars and setting a \u003ca href=\"https://www.cpuc.ca.gov/zev/\" target=\"_blank\" rel=\"noopener noreferrer\">target\u003c/a> of 5 million electric vehicles traversing California roads by 2030. But meeting that goal is going to be tough, with sales of EVs currently standing at only a \u003ca href=\"https://www.veloz.org/sales-dashboard/\" target=\"_blank\" rel=\"noopener noreferrer\">fraction of that total.\u003c/a>\u003c/p>\n\u003cp>Meanwhile, frustrated by the lack of progress in the fight against climate change, young people took to the streets the last couple of years. The Sunrise Movement, Youth vs. Apocalypse and other Bay Area advocacy groups participated in \u003ca href=\"https://www.kqed.org/science/1947584/live-blog-bay-area-climate-strike\" target=\"_blank\" rel=\"noopener noreferrer\">global climate strikes \u003c/a>protesting the failure of government, finance, industry and other institutions to address climate change.– \u003ca href=\"https://twitter.com/StarkKev\" target=\"_blank\" rel=\"noopener noreferrer\">Kevin Stark\u003c/a>\u003c/p>\n\u003cp>\u003cstrong>Medical Advances\u003c/strong>\u003c/p>\n\u003cp>The decade saw major advances in the treatment of HIV and cancer.\u003c/p>\n\u003cp>Over the last 10 years, scientists have perfected antiretroviral drugs, taken daily in a single pill by people who are HIV-positive. These drugs allow HIV patients to live relatively free of sickness, a far cry from the first decade of the epidemic, when the diagnosis was tantamount to a death sentence. No longer highly toxic, antiretrovirals now work so well they can lower a patient’s viral load to undetectable levels, making it untransmittable from one person to another. Another daily pill, called \u003ca href=\"https://www.sfaf.org/resource-library/prep/?utm_source=GoogleAds&utm_medium=CPC&utm_campaign=GoogleAds_UEqualsU_PrEP&gclid=CjwKCAiAluLvBRASEiwAAbX3GcnQ19OOhwWeCw4YFui4HMm-wM45wQzXB0fgh9a1hPAxzgkFYKnxRBoCsswQAvD_BwE\" target=\"_blank\" rel=\"noopener noreferrer\">PrEP,\u003c/a> can be used as a prophylactic against HIV exposure by people who are still free of the virus. Such major strides in treatment and prevention are why scientists are optimistic HIV will be eradicated altogether within the next decade.\u003c/p>\n\u003cp>For some types of cancer, a treatment called immunotherapy drastically improved survival and cure rates. For example, \u003ca href=\"https://www.kqed.org/futureofyou/444527/advanced-skin-cancer-was-once-a-death-sentence-immunotherapy-is-changing-that\" target=\"_blank\" rel=\"noopener noreferrer\">stage 4 melanoma \u003c/a>, which doesn’t respond to radiation or chemotherapy, used to mean \u003ca href=\"https://www.kqed.org/futureofyou/444527/advanced-skin-cancer-was-once-a-death-sentence-immunotherapy-is-changing-that\" target=\"_blank\" rel=\"noopener noreferrer\">certain death\u003c/a>, with patients surviving less than a year on average. But over the last decade, instead of burning or poisoning cancer cells to stop the disease, new medicines have unleashed the body’s natural defenses.\u003c/p>\n\u003cp>Normally the immune system recognizes disease-causing organisms. But cancer cells go undetected as harmful. New drugs, as well as \u003ca href=\"https://www.kqed.org/futureofyou/439584/new-gene-therapy-gives-teen-a-second-chance-after-cancer\" target=\"_blank\" rel=\"noopener noreferrer\">genetic engineering\u003c/a> techniques, make them visible and ripe for attack. Think of it like affixing a flag with the message “kill me” on cells that previously operated with impunity. Pancreatic, breast and prostate cancer, among other types, do not currently respond to immunotherapy, but scientists foresee a day when the treatment could be the primary weapon against an array of cancers.\u003c/p>\n\u003cp>\u003ca href=\"https://ww2.kqed.org/app/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1.jpg\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\"alignnone wp-image-1952602 size-complete_open_graph\" src=\"https://ww2.kqed.org/app/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1-1200x797.jpg\" alt=\"\" width=\"640\" height=\"425\" srcset=\"https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1-1200x797.jpg 1200w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1-160x106.jpg 160w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1-800x531.jpg 800w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1-768x510.jpg 768w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1-1020x677.jpg 1020w, https://cdn.kqed.org/wp-content/uploads/sites/35/2019/12/DESKTOP_CRISPR_171115-1.jpg 1280w\" sizes=\"(max-width: 640px) 100vw, 640px\">\u003c/a>\u003c/p>\n\u003cp>There may also be a day when doctors can eliminate genetic diseases altogether. A tool called \u003ca href=\"https://www.kqed.org/futureofyou/370/a-crispr-solution-to-bubble-boy-disease\" target=\"_blank\" rel=\"noopener noreferrer\">CRISPR \u003c/a>acts as a molecular scalpel that can make precise changes to genetic mutations giving rise to disease. Scientists hope to one day cure genetic conditions like blindness or sickle cell anemia before they even start. Though tinkering with our DNA raises all kinds of ethical questions about “\u003ca href=\"https://www.kqed.org/science/1934916/chinese-scientist-says-hes-first-to-create-genetically-modified-babies-using-crispr\" target=\"_blank\" rel=\"noopener noreferrer\">playing God\u003c/a>.”– \u003ca href=\"https://twitter.com/lesleywmcclurg\" target=\"_blank\" rel=\"noopener noreferrer\">Lesley McClurg\u003c/a>\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>\u003cstrong>Predictions Fulfilled\u003c/strong>\u003c/p>\n\u003cp>The decade saw some spectacular discoveries in space and physics, some of which had been predicted for decades. Theoretical foresight frequently falls short or remains unproven, but once in a while, it’s right on the money.\u003c/p>\n\u003cp>Two discoveries in particular should be remembered as a vindication of the human ability to understand and model the world.\u003c/p>\n\u003cp>In 2012, two teams at CERN, often referred to as the European Laboratory for Particle Physics, announced they had independently detected the Higgs boson. This is a particle associated with an energy field, called the Higgs field, that was theorized in the 1960s and ’70s as a solution to the question: How does matter obtain mass?\u003c/p>\n\u003cp>The answer: Through the action of an elementary particle, such as an electron or a quark, interacting with the Higgs field. The more the particle interacts, the more massive it is. And the boson? That’s the particle that the Higgs field emits. The detection of the Higgs boson proved that the Higgs field is real, and it was the final piece of the puzzle for the Standard Model, a set of equations describing how three of the four fundamental forces work. Now, only gravity remains unexplained.\u003c/p>\n\u003cp>The decade also saw the discovery of gravitational waves, predicted by none other than Albert Einstein in 1916. Einstein thought the acceleration of objects with enough mass would create ripples in the fabric of spacetime. And he thought right. About 100 years later, dual detectors that make up the Laser Interferometer Gravitational-Wave Observatory, or LIGO, registered those ripples in the form of the aftershock created by two black holes colliding.\u003c/p>\n\u003cp>Traveling far above Earth-bound detection instruments like LIGO, spacecraft originating on Earth reached interstellar space for the first time. These are the Voyager probes, each carrying a copy of the \u003ca href=\"https://voyager.jpl.nasa.gov/golden-record/\" target=\"_blank\" rel=\"noopener noreferrer\">Golden Record\u003c/a>, which holds images, music and greetings from Earth. — \u003ca href=\"https://twitter.com/DanielleVenton\" target=\"_blank\" rel=\"noopener noreferrer\">Danielle Venton\u003c/a>\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"floatright"},"numeric":["floatright"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/science/1952464/the-big-science-and-environment-stories-of-the-decade","authors":["6387"],"categories":["science_28","science_30","science_29","science_31","science_33","science_35","science_39","science_40","science_2873","science_42","science_3423","science_3947","science_3730"],"tags":["science_194","science_134","science_3370","science_660","science_4154","science_672","science_309","science_577","science_113"],"featImg":"science_1952606","label":"source_science_1952464"},"science_1944497":{"type":"posts","id":"science_1944497","meta":{"index":"posts_1591205157","site":"science","id":"1944497","score":null,"sort":[1562112271000]},"guestAuthors":[],"slug":"crispr-wipes-out-hiv-in-some-mice","title":"CRISPR Wipes Out HIV in Some Mice","publishDate":1562112271,"format":"standard","headTitle":"CRISPR Wipes Out HIV in Some Mice | KQED","labelTerm":{},"content":"\u003cp>For the millions of people infected with HIV, the best way to manage the disease is antiretroviral therapy, which can lower the amount of HIV replicating in the body to undetectable levels.\u003c/p>\n\u003carticle>\n\u003cdiv class=\"body-text\">\n\u003cp>But antiretroviral therapy (ART) can only manage HIV, never eliminate it — leading people to rely on the \u003ca href=\"https://aidsinfo.nih.gov/guidelines/html/1/adult-and-adolescent-arv/459/cost-considerations-and-antiretroviral-therapy\">expensive drugs\u003c/a> for decades. Plus if ART is halted by these patients, HIV bounces back and its levels rise in a matter of weeks. In 2017 the World Health Organization \u003ca href=\"https://www.who.int/gho/hiv/en/\">reported that of\u003c/a> 36.9 million people living with HIV, 21.7 million were taking ART.\u003c/p>\n\u003cp>A new study of mice charts a preliminary path to eliminating this medication dependency, through an injection of gene-editing \u003ca href=\"https://ghr.nlm.nih.gov/primer/genomicresearch/genomeediting\">CRISPR\u003c/a>.\u003c/p>\n\u003cp>Removing HIV from a person’s body is so hard because “once the virus infects cells [the] viral genome integrates into the host genome and then becomes part of our DNA,” said Kamel Khalili, a neurovirologist at Temple University who co-led the study.\u003c/p>\n\u003cp>Once this integration happens, ART can’t reverse it — at least not on its own. But Khalili and his colleagues found combining CRISPR, which can alter DNA, with ART can remove the lingering signs of HIV in a mouse model of the disease. The collaborative effort between researchers at Temple University and the University of Nebraska Medical Center was \u003ca href=\"https://www.nature.com/articles/s41467-019-10366-y\">reported today in Nature Communications\u003c/a>.\u003c/p>\n\u003cp>Results in mouse models do not always translate into effective treatments in humans, but Fyodor Urnov says this study is an “important next step” in addressing a disease like HIV with a technique.\u003c/p>\n\u003cp>“Gene editing is the first-ever technology we have had to address disease at the DNA level,” said Urnov, who works at the Innovative Genomics Institute at the University of California Berkeley and was not involved in the study.\u003c/p>\n\u003cp>CRISPR, which scientists can program to cut DNA at specific sites, has garnered attention as a potential cure for genetic diseases, such as \u003ca href=\"https://cysticfibrosisnewstoday.com/crisprcas9-approach-for-cystic-fibrosis/\">cystic fibrosis\u003c/a> and \u003ca href=\"https://directorsblog.nih.gov/2019/02/26/more-progress-toward-gene-editing-for-kids-with-muscular-dystrophy/\">muscular dystrophy\u003c/a>. Using CRISPR and ART to develop an HIV cure could eventually eliminate the cost and distribution barriers that come with current treatments. To date, \u003ca href=\"https://www.theguardian.com/society/2019/mar/05/london-patient-becomes-second-man-to-be-cleared-of-aids-virus\">only two people have been cured of HIV\u003c/a>after receiving stem cell therapy to treat cancer. This expensive and invasive treatment has failed in every other HIV patient.\u003c/p>\n\u003cp>But CRISPR comes with its own caveats — namely, at the moment it isn’t as precise as many in the general public might think.\u003c/p>\n\u003ch2>What the Study Did\u003c/h2>\n\u003cp>The researchers used “humanized” mice, meaning mice were infused with the type of human immune cells that HIV infects.\u003c/p>\n\u003cp>In three separate trials, HIV-infected mice were given one of three injection therapies: a slow-release version of the common HIV drug ART, the CRISPR protein that finds and cuts genome-incorporated HIV, or a combination of the two.\u003c/p>\n\u003cp>After four weeks of ART treatment, the researchers dispensed CRISPR into the mice by packaging the protein inside of a completely separate virus, called adeno-associated virus, or AAV. AAV doesn’t cause illness, but it acts like a mail carrier, increasing the circulation of CRISPR. CRISPR then becomes more likely to find and cut out all of the HIV DNA, an essential step to prevent the disease from rebounding.\u003c/p>\n\u003cp>The researchers waited eight weeks after all the mice were taken off of ART, then searched for traces of HIV genetic material in blood, spleen, kidneys, gut, lungs, bone marrow and the brain.\u003c/p>\n\u003cp>After eight ART-free weeks, more than 30 percent of the mice that received ART and CRISPR lacked detectable amounts of HIV in any of the tissues the researchers studied.\u003c/p>\n\u003cp>In contrast, HIV was still detectable in all of the other mice, including those that were treated with ART or CRISPR alone.\u003c/p>\n\u003ch2>A Cautious Way Forward\u003c/h2>\n\u003cp>Though the researchers used “humanized mice,” the technology has a long way to go. “Clinical trials…will not start tonight. It will take a few years,” said Urnov. However, Khalili revealed that early data from preliminary trials in monkeys looks promising.\u003c/p>\n\u003cp>Khalili and his colleagues have applied to the U.S. Food and Drug Administration for permission to start human clinical trials as early as next year. Khalili has also launched a for-profit company that is developing CRISPR-based technology to treat disease.\u003c/p>\n\u003cp>That the technology is moving this fast concerns Zandrea Ambrose, a retrovirologist at the University of Pittsburgh, who was not involved in the study. CRISPR comes with a downside, in that it sometimes accidentally cuts the wrong gene.\u003c/p>\n\u003cp>Relative to other gene editors, CRISPR has fewer of these “off-target effects” as they’re called, but even a single error is worrisome. If CRISPR makes a hazardous mutation, it could disrupt any cell’s normal behavior and cause an inadvertent disease.\u003c/p>\n\u003cp>With billions of letters in the genome, it’s going to take a lot of work to avoid all possible off-target effects, Ambrose said. This study is promising, she added, but scientists in the CRISPR field need to get better at detecting these potential accidents.\u003c/p>\n\u003cp>Before clinical trials can begin, she said, researchers need to be sure these accidents won’t occur in humans by first testing them in animals. When researchers scanned the DNA from the “cured” mice, they didn’t find any signs that CRISPR had made cuts outside of the HIV DNA. But they could tell that CRISPR had made cuts within the HIV DNA, meaning the instructions for making new virus were broken.\u003c/p>\n\u003cp>Along with possible off-target effects, Ambrose worries that CRISPR, enclosed in an AAV virus, will remain in the body long after its job is done. If that’s the case, she says “there’s no way to turn” the CRISPR editing off, increasing the chances of an off-target cut.\u003c/p>\n\u003cp>But Khalili is confident that CRISPR is only cutting the DNA where it’s supposed to, based on searches for the “footprints” CRISPR leaves on DNA when it cuts. And CRISPR \u003ca href=\"https://www.pbs.org/newshour/science/jumping-genes-could-help-crispr-replace-disease-causing-dna-study-finds\" target=\"_blank\" rel=\"noopener\">continues to improve everyday\u003c/a>.\u003c/p>\n\u003cp>While a comprehensive, single-shot cure for HIV may be years away, Khalili is encouraged that this milestone “will give those affected hope.”\u003c/p>\n\u003cp>\u003cem>\u003ca href=\"https://www.pbs.org/newshour/science/crispr-gene-editing-eliminates-hiv-in-some-mice-what-does-it-mean-for-humans\">This story\u003c/a> was originally published on PBS Newshour.\u003c/em>\u003c/p>\n\u003c/div>\n\u003c/article>\n\u003cp>[ad fullwidth]\u003c/p>\u003cp>[ad floatright]\u003c/p>\n","blocks":[],"excerpt":"The new study could be an “important next step” in developing a pathway for addressing HIV with a gene-editing technique. ","status":"publish","parent":0,"modified":1704848541,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":27,"wordCount":1074},"headData":{"title":"CRISPR Wipes Out HIV in Some Mice | KQED","description":"The new study could be an “important next step” in developing a pathway for addressing HIV with a gene-editing technique. ","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":""},"source":"PBS Newshour","sticky":false,"nprByline":"Berly McCoy \u003cbr/> PBS Newshour \u003cbr>","path":"/science/1944497/crispr-wipes-out-hiv-in-some-mice","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>For the millions of people infected with HIV, the best way to manage the disease is antiretroviral therapy, which can lower the amount of HIV replicating in the body to undetectable levels.\u003c/p>\n\u003carticle>\n\u003cdiv class=\"body-text\">\n\u003cp>But antiretroviral therapy (ART) can only manage HIV, never eliminate it — leading people to rely on the \u003ca href=\"https://aidsinfo.nih.gov/guidelines/html/1/adult-and-adolescent-arv/459/cost-considerations-and-antiretroviral-therapy\">expensive drugs\u003c/a> for decades. Plus if ART is halted by these patients, HIV bounces back and its levels rise in a matter of weeks. In 2017 the World Health Organization \u003ca href=\"https://www.who.int/gho/hiv/en/\">reported that of\u003c/a> 36.9 million people living with HIV, 21.7 million were taking ART.\u003c/p>\n\u003cp>A new study of mice charts a preliminary path to eliminating this medication dependency, through an injection of gene-editing \u003ca href=\"https://ghr.nlm.nih.gov/primer/genomicresearch/genomeediting\">CRISPR\u003c/a>.\u003c/p>\n\u003cp>Removing HIV from a person’s body is so hard because “once the virus infects cells [the] viral genome integrates into the host genome and then becomes part of our DNA,” said Kamel Khalili, a neurovirologist at Temple University who co-led the study.\u003c/p>\n\u003cp>Once this integration happens, ART can’t reverse it — at least not on its own. But Khalili and his colleagues found combining CRISPR, which can alter DNA, with ART can remove the lingering signs of HIV in a mouse model of the disease. The collaborative effort between researchers at Temple University and the University of Nebraska Medical Center was \u003ca href=\"https://www.nature.com/articles/s41467-019-10366-y\">reported today in Nature Communications\u003c/a>.\u003c/p>\n\u003cp>Results in mouse models do not always translate into effective treatments in humans, but Fyodor Urnov says this study is an “important next step” in addressing a disease like HIV with a technique.\u003c/p>\n\u003cp>“Gene editing is the first-ever technology we have had to address disease at the DNA level,” said Urnov, who works at the Innovative Genomics Institute at the University of California Berkeley and was not involved in the study.\u003c/p>\n\u003cp>CRISPR, which scientists can program to cut DNA at specific sites, has garnered attention as a potential cure for genetic diseases, such as \u003ca href=\"https://cysticfibrosisnewstoday.com/crisprcas9-approach-for-cystic-fibrosis/\">cystic fibrosis\u003c/a> and \u003ca href=\"https://directorsblog.nih.gov/2019/02/26/more-progress-toward-gene-editing-for-kids-with-muscular-dystrophy/\">muscular dystrophy\u003c/a>. Using CRISPR and ART to develop an HIV cure could eventually eliminate the cost and distribution barriers that come with current treatments. To date, \u003ca href=\"https://www.theguardian.com/society/2019/mar/05/london-patient-becomes-second-man-to-be-cleared-of-aids-virus\">only two people have been cured of HIV\u003c/a>after receiving stem cell therapy to treat cancer. This expensive and invasive treatment has failed in every other HIV patient.\u003c/p>\n\u003cp>But CRISPR comes with its own caveats — namely, at the moment it isn’t as precise as many in the general public might think.\u003c/p>\n\u003ch2>What the Study Did\u003c/h2>\n\u003cp>The researchers used “humanized” mice, meaning mice were infused with the type of human immune cells that HIV infects.\u003c/p>\n\u003cp>In three separate trials, HIV-infected mice were given one of three injection therapies: a slow-release version of the common HIV drug ART, the CRISPR protein that finds and cuts genome-incorporated HIV, or a combination of the two.\u003c/p>\n\u003cp>After four weeks of ART treatment, the researchers dispensed CRISPR into the mice by packaging the protein inside of a completely separate virus, called adeno-associated virus, or AAV. AAV doesn’t cause illness, but it acts like a mail carrier, increasing the circulation of CRISPR. CRISPR then becomes more likely to find and cut out all of the HIV DNA, an essential step to prevent the disease from rebounding.\u003c/p>\n\u003cp>The researchers waited eight weeks after all the mice were taken off of ART, then searched for traces of HIV genetic material in blood, spleen, kidneys, gut, lungs, bone marrow and the brain.\u003c/p>\n\u003cp>After eight ART-free weeks, more than 30 percent of the mice that received ART and CRISPR lacked detectable amounts of HIV in any of the tissues the researchers studied.\u003c/p>\n\u003cp>In contrast, HIV was still detectable in all of the other mice, including those that were treated with ART or CRISPR alone.\u003c/p>\n\u003ch2>A Cautious Way Forward\u003c/h2>\n\u003cp>Though the researchers used “humanized mice,” the technology has a long way to go. “Clinical trials…will not start tonight. It will take a few years,” said Urnov. However, Khalili revealed that early data from preliminary trials in monkeys looks promising.\u003c/p>\n\u003cp>Khalili and his colleagues have applied to the U.S. Food and Drug Administration for permission to start human clinical trials as early as next year. Khalili has also launched a for-profit company that is developing CRISPR-based technology to treat disease.\u003c/p>\n\u003cp>That the technology is moving this fast concerns Zandrea Ambrose, a retrovirologist at the University of Pittsburgh, who was not involved in the study. CRISPR comes with a downside, in that it sometimes accidentally cuts the wrong gene.\u003c/p>\n\u003cp>Relative to other gene editors, CRISPR has fewer of these “off-target effects” as they’re called, but even a single error is worrisome. If CRISPR makes a hazardous mutation, it could disrupt any cell’s normal behavior and cause an inadvertent disease.\u003c/p>\n\u003cp>With billions of letters in the genome, it’s going to take a lot of work to avoid all possible off-target effects, Ambrose said. This study is promising, she added, but scientists in the CRISPR field need to get better at detecting these potential accidents.\u003c/p>\n\u003cp>Before clinical trials can begin, she said, researchers need to be sure these accidents won’t occur in humans by first testing them in animals. When researchers scanned the DNA from the “cured” mice, they didn’t find any signs that CRISPR had made cuts outside of the HIV DNA. But they could tell that CRISPR had made cuts within the HIV DNA, meaning the instructions for making new virus were broken.\u003c/p>\n\u003cp>Along with possible off-target effects, Ambrose worries that CRISPR, enclosed in an AAV virus, will remain in the body long after its job is done. If that’s the case, she says “there’s no way to turn” the CRISPR editing off, increasing the chances of an off-target cut.\u003c/p>\n\u003cp>But Khalili is confident that CRISPR is only cutting the DNA where it’s supposed to, based on searches for the “footprints” CRISPR leaves on DNA when it cuts. And CRISPR \u003ca href=\"https://www.pbs.org/newshour/science/jumping-genes-could-help-crispr-replace-disease-causing-dna-study-finds\" target=\"_blank\" rel=\"noopener\">continues to improve everyday\u003c/a>.\u003c/p>\n\u003cp>While a comprehensive, single-shot cure for HIV may be years away, Khalili is encouraged that this milestone “will give those affected hope.”\u003c/p>\n\u003cp>\u003cem>\u003ca href=\"https://www.pbs.org/newshour/science/crispr-gene-editing-eliminates-hiv-in-some-mice-what-does-it-mean-for-humans\">This story\u003c/a> was originally published on PBS Newshour.\u003c/em>\u003c/p>\n\u003c/div>\n\u003c/article>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"floatright"},"numeric":["floatright"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/science/1944497/crispr-wipes-out-hiv-in-some-mice","authors":["byline_science_1944497"],"categories":["science_2874","science_39","science_3890","science_40"],"tags":["science_1287","science_660"],"featImg":"science_1944503","label":"source_science_1944497"},"science_1938724":{"type":"posts","id":"science_1938724","meta":{"index":"posts_1591205157","site":"science","id":"1938724","score":null,"sort":[1551805373000]},"guestAuthors":[],"slug":"second-patient-is-effectively-cured-of-hiv","title":"Second Patient is Reported Effectively Cured of HIV","publishDate":1551805373,"format":"standard","headTitle":"Second Patient is Reported Effectively Cured of HIV | KQED","labelTerm":{},"content":"\u003cp class=\"danger-zone\">For the second time, doctors appear to have put HIV into “sustained remission” with a stem cell transplant — effectively curing the recipient.\u003c/p>\n\u003cp class=\"danger-zone\">Their work, which was published in \u003cem>Nature\u003c/em> and will be presented at the annual Conference on Retroviruses and Opportunistic Infections in Seattle on Tuesday, may encourage scientists working on new gene therapies based on similar principles and give hope to those living with the infection.\u003c/p>\n\u003cp class=\"danger-zone\">The case comes nearly 10 years after Timothy Ray Brown announced he was the so-called “Berlin Patient” — the first person who was functionally cured of HIV and able to stop taking antiretroviral drugs after an intensive round of chemotherapy and radiation and two bone marrow transplants.\u003c/p>\n\u003cp class=\"danger-zone\">The person who received this latest transplant in London has not taken antiretroviral drugs since September 2017; he is not identified in the paper.\u003c/p>\n\u003cp class=\"danger-zone\">“Those of us in the field have been waiting for a second cure via this approach,” said Dr. Keith Jerome, one of the leaders of HIV cure research at the Fred Hutchinson Cancer Research Center. “As long as Timothy Brown was the only [one], we’d have always wondered if there something unique about it.”\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp class=\"danger-zone\">Jerome was not involved in the research published Tuesday.\u003c/p>\n\u003cp class=\"danger-zone\">The researchers behind the paper are from an array of British, Spanish, Dutch and Singaporean institutions; the lead author is \u003ca href=\"https://www.ucl.ac.uk/infection-immunity/people/professor-ravindra-gupta\" target=\"_blank\" rel=\"noopener\">Ravindra K. Gupta\u003c/a>, who is affiliated with the University of Cambridge, Imperial College London, and University College London.\u003c/p>\n\u003cp>Experts caution that this news should not be interpreted as having found a cure for everyone with HIV.\u003c/p>\n\u003cp>“It doesn’t change things for the average person with HIV right now,” said Dr. Bruce Walker, the director of the \u003ca href=\"http://www.ragoninstitute.org/\" target=\"_blank\" rel=\"noopener\">Ragon Institute\u003c/a>, a research institute affiliated with Massachusetts General Hospital, Harvard, and MIT that specializes in HIV/AIDS and infectious diseases. (Walker was also uninvolved with the Nature research.) “It does change things in terms of the research agenda, because it further indicates that this is a potentially viable pathway forward to achieve a cure.”\u003c/p>\n\u003cp>That potentially viable pathway runs through a receptor called CCR5. CCR5 is one of a handful of receptors that HIV can use to get into a particular kind of cell.\u003c/p>\n\u003cp>Those cells, called CD4-positive T-cells, are vital to a person’s immune system. “You can sort of think of [these] cells as the generals that are helping to orchestrate an effective defense,” Walker said. “If they’re not there, things tend to go haywire.”\u003c/p>\n\u003cp>Some people have a particular mutation in the genes that encode the CCR5 receptor that prevents the HIV virus from using it to get in to these T-cells — and no entry means no infection.\u003c/p>\n\u003cp>The person whose case is described in Tuesday’s paper got a transplant of the stem cells that produce blood and immune system cells — typically found in a person’s bone marrow — with this mutation from a donor; about \u003ca href=\"https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.0030339\" target=\"_blank\" rel=\"noopener\">10 percent of people\u003c/a> in some Northern European countries naturally carry the mutation.\u003c/p>\n\u003cp>Like Timothy Brown, this person’s transplant happened as part of his cancer treatment. After doctors diagnosed him with an advanced case of Hodgkin’s lymphoma, the person went through chemotherapy and a transplant from a donor picked in part for his or her CCR5 mutation.\u003c/p>\n\u003cp>Unlike Brown, though, this person’s cancer treatment didn’t involve full-body radiation, and his chemotherapy was also far gentler. That’s encouraging, but Walker, the Ragon researcher, noted the risks from even this regimen were still too great to offer these kind of stem cell transplants outside of cancer treatment. Given that the life expectancy for people with HIV on antiretroviral medications has increased dramatically — and, \u003ca href=\"https://www.statnews.com/2017/05/10/hiv-life-expectancy-study/\">one study found\u003c/a>, is now a nearly normal one, “there’s a very high bar for subjecting people to any additional risk,” he said. “This wasn’t without risk, but was much less [risky].”\u003c/p>\n\u003cp>The CCR5 mutation’s virus-blocking power can be simulated with a drug. Since 2007, Viiv Healthcare, a joint venture initially formed by Pfizer and GlaxoSmithKline, has marketed a drug, called Selzentry in the United States, that prevents HIV from using the CCR5 receptor by binding to the receptor itself.\u003c/p>\n\u003cp>But that drug has the same issues that most drugs have: it needs to be taken every day. “Just like any other suppressive therapy for HIV, as soon as a person stops taking the drug, the virus comes roaring back,” said Fred Hutchinson’s Jerome. In an ideal world, the treatment for HIV would look more like Luxturna, a recently approved gene therapy for a form of blindness \u003ca href=\"https://www.statnews.com/2018/03/21/gene-therapy-luxturna-launch/\">that’s injected just once\u003c/a> into a person’s eye, and less like Lipitor.\u003c/p>\n\u003cp>“The beauty of a transplantation or a gene therapy approach targeting CCR5 — that’s the kind of thing that looks like you can do it once, and then the person’s cured,” Jerome said. “They don’t need to worry about the virus any more, they don’t need to worry about their access to drugs or remembering to take it every day.”\u003c/p>\n\u003cp>The most infamous gene therapy experiment targeting CCR5 is undoubtedly He Jiankui’s, which \u003ca href=\"https://www.statnews.com/2018/11/26/claim-of-crispred-baby-girls-stuns-genome-editing-summit/\">created human embryos\u003c/a> — and, later, actual children — with a CRISPR-mutated CCR5 gene. His announcement triggered a massive backlash from \u003ca href=\"https://www.statnews.com/2019/01/24/crispr-babies-show-need-for-more-specific-rules/\">scientists, ethicists\u003c/a>, and \u003ca href=\"https://www.statnews.com/2019/02/25/crispr-babies-study-china-government-funding/\">the Chinese government\u003c/a>.\u003c/p>\n\u003cp>Less controversial gene editing work is ongoing, too. Sangamo Therapeutics, for example, is working on genetically editing \u003ca href=\"https://www.sangamo.com/pipeline\" target=\"_blank\" rel=\"noopener\">T-cells and stem cells\u003c/a> to carry the CCR5 mutation. According to the company’s pipeline chart, that treatment is in early-stage clinical trials.\u003c/p>\n\u003cp>Tuesday’s paper — and the concept of using CCR5 as the basis for future treatments — comes with caveats. For one thing, not all HIV viruses use CCR5 receptors to get into a cell; viruses that use other co-receptors exist, though they’re rarer. And even if a treatment can stop the virus from infecting new cells, it tends to linger in previously infected ones.\u003c/p>\n\u003cp>“The virus may still be hiding out someplace and it may come back 10 years from now,” Walker noted. “You can never be absolutely certain that a cure has been achieved.”\u003c/p>\n\u003cp>But to Jerome, the Fred Hutchinson Cancer Research Center researcher, a new report of even an uncertain cure is meaningful. “It’s a reminder about how difficult this challenge is and how difficult this virus is to deal with, but at the same time, it provides hope,” he said.\u003c/p>\n\u003cp>“Now there’s not one, but two people that others living with HIV can look toward for encouragement,” he added.\u003c/p>\n\u003cp>\u003cem>\u003cspan style=\"font-weight: 400\">This \u003ca href=\"https://www.statnews.com/2019/03/04/second-person-effectively-cured-of-hiv/?utm_source=STAT+Newsletters&utm_campaign=68de2d8f55-MR_COPY_08&utm_medium=email&utm_term=0_8cab1d7961-68de2d8f55-149648249\" target=\"_blank\" rel=\"noopener\">story\u003c/a> was originally published by\u003ca href=\"https://www.statnews.com/\" target=\"_blank\" rel=\"noopener\"> STAT\u003c/a>, an online publication of Boston Globe Media that covers health, medicine, and scientific discovery. \u003c/span>\u003c/em>\u003c/p>\n\u003cp>[ad floatright]\u003c/p>\n\u003cp> \u003c/p>\n\n","blocks":[],"excerpt":"For the second time, doctors appear to have put HIV into “sustained remission” with a stem cell transplant. The treatment comes 10 years after the cure of Timothy Ray Brown, the so-called Berlin Patient, pictured above.","status":"publish","parent":0,"modified":1704848821,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":20,"wordCount":1201},"headData":{"title":"Second Patient is Reported Effectively Cured of HIV | KQED","description":"For the second time, doctors appear to have put HIV into “sustained remission” with a stem cell transplant. The treatment comes 10 years after the cure of Timothy Ray Brown, the so-called Berlin Patient, pictured above.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":""},"source":"STAT","sticky":false,"nprByline":"Kate Sheridan\u003cbr />STAT","path":"/science/1938724/second-patient-is-effectively-cured-of-hiv","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp class=\"danger-zone\">For the second time, doctors appear to have put HIV into “sustained remission” with a stem cell transplant — effectively curing the recipient.\u003c/p>\n\u003cp class=\"danger-zone\">Their work, which was published in \u003cem>Nature\u003c/em> and will be presented at the annual Conference on Retroviruses and Opportunistic Infections in Seattle on Tuesday, may encourage scientists working on new gene therapies based on similar principles and give hope to those living with the infection.\u003c/p>\n\u003cp class=\"danger-zone\">The case comes nearly 10 years after Timothy Ray Brown announced he was the so-called “Berlin Patient” — the first person who was functionally cured of HIV and able to stop taking antiretroviral drugs after an intensive round of chemotherapy and radiation and two bone marrow transplants.\u003c/p>\n\u003cp class=\"danger-zone\">The person who received this latest transplant in London has not taken antiretroviral drugs since September 2017; he is not identified in the paper.\u003c/p>\n\u003cp class=\"danger-zone\">“Those of us in the field have been waiting for a second cure via this approach,” said Dr. Keith Jerome, one of the leaders of HIV cure research at the Fred Hutchinson Cancer Research Center. “As long as Timothy Brown was the only [one], we’d have always wondered if there something unique about it.”\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp class=\"danger-zone\">Jerome was not involved in the research published Tuesday.\u003c/p>\n\u003cp class=\"danger-zone\">The researchers behind the paper are from an array of British, Spanish, Dutch and Singaporean institutions; the lead author is \u003ca href=\"https://www.ucl.ac.uk/infection-immunity/people/professor-ravindra-gupta\" target=\"_blank\" rel=\"noopener\">Ravindra K. Gupta\u003c/a>, who is affiliated with the University of Cambridge, Imperial College London, and University College London.\u003c/p>\n\u003cp>Experts caution that this news should not be interpreted as having found a cure for everyone with HIV.\u003c/p>\n\u003cp>“It doesn’t change things for the average person with HIV right now,” said Dr. Bruce Walker, the director of the \u003ca href=\"http://www.ragoninstitute.org/\" target=\"_blank\" rel=\"noopener\">Ragon Institute\u003c/a>, a research institute affiliated with Massachusetts General Hospital, Harvard, and MIT that specializes in HIV/AIDS and infectious diseases. (Walker was also uninvolved with the Nature research.) “It does change things in terms of the research agenda, because it further indicates that this is a potentially viable pathway forward to achieve a cure.”\u003c/p>\n\u003cp>That potentially viable pathway runs through a receptor called CCR5. CCR5 is one of a handful of receptors that HIV can use to get into a particular kind of cell.\u003c/p>\n\u003cp>Those cells, called CD4-positive T-cells, are vital to a person’s immune system. “You can sort of think of [these] cells as the generals that are helping to orchestrate an effective defense,” Walker said. “If they’re not there, things tend to go haywire.”\u003c/p>\n\u003cp>Some people have a particular mutation in the genes that encode the CCR5 receptor that prevents the HIV virus from using it to get in to these T-cells — and no entry means no infection.\u003c/p>\n\u003cp>The person whose case is described in Tuesday’s paper got a transplant of the stem cells that produce blood and immune system cells — typically found in a person’s bone marrow — with this mutation from a donor; about \u003ca href=\"https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.0030339\" target=\"_blank\" rel=\"noopener\">10 percent of people\u003c/a> in some Northern European countries naturally carry the mutation.\u003c/p>\n\u003cp>Like Timothy Brown, this person’s transplant happened as part of his cancer treatment. After doctors diagnosed him with an advanced case of Hodgkin’s lymphoma, the person went through chemotherapy and a transplant from a donor picked in part for his or her CCR5 mutation.\u003c/p>\n\u003cp>Unlike Brown, though, this person’s cancer treatment didn’t involve full-body radiation, and his chemotherapy was also far gentler. That’s encouraging, but Walker, the Ragon researcher, noted the risks from even this regimen were still too great to offer these kind of stem cell transplants outside of cancer treatment. Given that the life expectancy for people with HIV on antiretroviral medications has increased dramatically — and, \u003ca href=\"https://www.statnews.com/2017/05/10/hiv-life-expectancy-study/\">one study found\u003c/a>, is now a nearly normal one, “there’s a very high bar for subjecting people to any additional risk,” he said. “This wasn’t without risk, but was much less [risky].”\u003c/p>\n\u003cp>The CCR5 mutation’s virus-blocking power can be simulated with a drug. Since 2007, Viiv Healthcare, a joint venture initially formed by Pfizer and GlaxoSmithKline, has marketed a drug, called Selzentry in the United States, that prevents HIV from using the CCR5 receptor by binding to the receptor itself.\u003c/p>\n\u003cp>But that drug has the same issues that most drugs have: it needs to be taken every day. “Just like any other suppressive therapy for HIV, as soon as a person stops taking the drug, the virus comes roaring back,” said Fred Hutchinson’s Jerome. In an ideal world, the treatment for HIV would look more like Luxturna, a recently approved gene therapy for a form of blindness \u003ca href=\"https://www.statnews.com/2018/03/21/gene-therapy-luxturna-launch/\">that’s injected just once\u003c/a> into a person’s eye, and less like Lipitor.\u003c/p>\n\u003cp>“The beauty of a transplantation or a gene therapy approach targeting CCR5 — that’s the kind of thing that looks like you can do it once, and then the person’s cured,” Jerome said. “They don’t need to worry about the virus any more, they don’t need to worry about their access to drugs or remembering to take it every day.”\u003c/p>\n\u003cp>The most infamous gene therapy experiment targeting CCR5 is undoubtedly He Jiankui’s, which \u003ca href=\"https://www.statnews.com/2018/11/26/claim-of-crispred-baby-girls-stuns-genome-editing-summit/\">created human embryos\u003c/a> — and, later, actual children — with a CRISPR-mutated CCR5 gene. His announcement triggered a massive backlash from \u003ca href=\"https://www.statnews.com/2019/01/24/crispr-babies-show-need-for-more-specific-rules/\">scientists, ethicists\u003c/a>, and \u003ca href=\"https://www.statnews.com/2019/02/25/crispr-babies-study-china-government-funding/\">the Chinese government\u003c/a>.\u003c/p>\n\u003cp>Less controversial gene editing work is ongoing, too. Sangamo Therapeutics, for example, is working on genetically editing \u003ca href=\"https://www.sangamo.com/pipeline\" target=\"_blank\" rel=\"noopener\">T-cells and stem cells\u003c/a> to carry the CCR5 mutation. According to the company’s pipeline chart, that treatment is in early-stage clinical trials.\u003c/p>\n\u003cp>Tuesday’s paper — and the concept of using CCR5 as the basis for future treatments — comes with caveats. For one thing, not all HIV viruses use CCR5 receptors to get into a cell; viruses that use other co-receptors exist, though they’re rarer. And even if a treatment can stop the virus from infecting new cells, it tends to linger in previously infected ones.\u003c/p>\n\u003cp>“The virus may still be hiding out someplace and it may come back 10 years from now,” Walker noted. “You can never be absolutely certain that a cure has been achieved.”\u003c/p>\n\u003cp>But to Jerome, the Fred Hutchinson Cancer Research Center researcher, a new report of even an uncertain cure is meaningful. “It’s a reminder about how difficult this challenge is and how difficult this virus is to deal with, but at the same time, it provides hope,” he said.\u003c/p>\n\u003cp>“Now there’s not one, but two people that others living with HIV can look toward for encouragement,” he added.\u003c/p>\n\u003cp>\u003cem>\u003cspan style=\"font-weight: 400\">This \u003ca href=\"https://www.statnews.com/2019/03/04/second-person-effectively-cured-of-hiv/?utm_source=STAT+Newsletters&utm_campaign=68de2d8f55-MR_COPY_08&utm_medium=email&utm_term=0_8cab1d7961-68de2d8f55-149648249\" target=\"_blank\" rel=\"noopener\">story\u003c/a> was originally published by\u003ca href=\"https://www.statnews.com/\" target=\"_blank\" rel=\"noopener\"> STAT\u003c/a>, an online publication of Boston Globe Media that covers health, medicine, and scientific discovery. \u003c/span>\u003c/em>\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"floatright"},"numeric":["floatright"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp> \u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/science/1938724/second-patient-is-effectively-cured-of-hiv","authors":["byline_science_1938724"],"categories":["science_39","science_3890","science_40"],"tags":["science_3370","science_660","science_3838"],"featImg":"science_1938726","label":"source_science_1938724"},"science_1934916":{"type":"posts","id":"science_1934916","meta":{"index":"posts_1591205157","site":"science","id":"1934916","score":null,"sort":[1543340457000]},"guestAuthors":[],"slug":"chinese-scientist-says-hes-first-to-create-genetically-modified-babies-using-crispr","title":"Chinese Scientist Says He's First to Create Genetically Modified Babies Using CRISPR","publishDate":1543340457,"format":"standard","headTitle":"Chinese Scientist Says He’s First to Create Genetically Modified Babies Using CRISPR | KQED","labelTerm":{},"content":"\u003cp>\u003cem>Editor’s note: This story was updated at 11:52 a.m. to add information about an ethics committee investigation into the DNA-editing experiment.\u003c/em>\u003c/p>\n\u003cp>For the first time, a scientist claims to have used a powerful new gene-editing technique to create genetically modified human babies.\u003c/p>\n\u003cp>The scientist, \u003ca href=\"http://www.sustc-genome.org.cn/\">He Jiankui \u003c/a>of the Southern University of Science and Technology in Shenzhen, China, says he used human embryos modified with the gene-editing technique \u003ca href=\"https://www.kqed.org/futureofyou/tag/crispr\">CRISPR\u003c/a> to create twin girls.\u003c/p>\n\u003cp>[contextly_sidebar id=”Bg3RvL4c0cugPpkycfYJRPou7iSqojCI”]”Two beautiful little Chinese girls name Lulu and Nana came crying into the world as healthy as any other babies a few weeks ago,” He says in a \u003ca href=\"https://www.youtube.com/watch?v=th0vnOmFltc&app=desktop\">video \u003c/a>posted online. “The babies are home now with their mom Grace and their dad Mark.”\u003c/p>\n\u003cp>He says his team performed “gene surgery” on embryos created from their parents’ sperm and eggs to protect the children from the human immunodeficiency virus, \u003ca href=\"https://www.cdc.gov/hiv/basics/\">HIV\u003c/a>, which causes AIDS. The children’s father is HIV-positive.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>https://www.youtube.com/watch?v=aezxaOn0efE\u003c/p>\n\u003cp>“When Lulu and Nana were just a single cell, this surgery removed a doorway through which HIV enter to infect people,” He says in the video, one of several \u003ca href=\"https://www.youtube.com/channel/UCn_Elifynj3LrubPKHXecwQ\">posted online\u003c/a> to justify and explain the work.\u003c/p>\n\u003cp>Because the research has not yet been published in a scientific journal or carefully vetted by other scientists, many researchers and bioethicists remain cautious about the claim.\u003c/p>\n\u003cp>But, if true, many said the move would be historic, comparing it to the birth of \u003ca href=\"https://www.louisejoybrown.com/\">Louise Brown\u003c/a>, the first baby created through in-vitro fertilization, IVF.\u003c/p>\n\u003cp>“This event might be analogous to Louise Brown in 1978,” wrote \u003ca href=\"http://arep.med.harvard.edu/gmc/\">George Church\u003c/a>, a prominent Harvard geneticist, in an email. “Both anecdotal — yet healthy baby girls can have an impact,” Church wrote.\u003c/p>\n\u003cp>Meanwhile, He is now facing \u003ca href=\"http://tech.sina.com.cn/d/f/2018-11-26/doc-ihmutuec3839378.shtml\">investigation\u003c/a> by a local medical ethics board to see whether his experiment broke Chinese laws or regulations.\u003c/p>\n\u003cp>The university where He worked issued a \u003ca href=\"http://sustc.edu.cn/en/info_focus/2871\">statement\u003c/a> that officials were “deeply shocked” by the experiment, which it stressed was conducted elsewhere. He, the statement says, has been on unpaid leave from the university.\u003c/p>\n\u003cp>Church and He are among hundreds of scientists gathering at the \u003ca href=\"http://www.nationalacademies.org/gene-editing/2nd_summit/index.htm\">Second International Summit on Human Gene Editing\u003c/a> in Hong Kong. The summit was organized try to reach a global consensus on whether and how it would be ethical to create genetically modified human beings with CRISPR.\u003c/p>\n\u003cp>The claims by He sparked immediate widespread criticism from attendees at the summit and elsewhere.\u003c/p>\n\u003cp>“This work is a break from the cautious and transparent approach of the global scientific community’s application of CRISPR-Cas9 for human germline editing,” \u003ca href=\"http://doudnalab.org/\">Jennifer Doudna\u003c/a>, a biochemist at the University of California, Berkeley, said in an interview. Doudna helped discover CRISPR and organize the summit.\u003c/p>\n\u003cp>[contextly_sidebar id=”lnQiNGycmxQjTqQV1wOUw35FnUBG9rgb”]”All of us that are here at this conference are struggling to figure out what was done and also whether the process was done properly. We just don’t know yet,” Doudna says.\u003c/p>\n\u003cp>But the claim “really reinforces the urgent need to confine the use of gene-editing in human embryos to settings where there’s a clear unmet medical need and where there’s no alternative viable approach,” says Doudna. She doesn’t think that is the case in this situation.\u003c/p>\n\u003cp>“If this was done to avoid HIV infection, there are alternative ways to prevent infection that are already effective,” Doudna says, such as “washing” the sperm of infected sperm donors to eliminate HIV. “Why would you use this instead of an already established approach?”\u003c/p>\n\u003cp>For their research, He and his colleagues say they used CRISPR to make changes in one-day old embryos in a gene called \u003ca href=\"https://ghr.nlm.nih.gov/gene/CCR5\">CCR5\u003c/a>. The CCR5 gene enables HIV to enter and infect immune system cells. Scientists have long searched for ways to block this pathway to protect people from HIV.\u003c/p>\n\u003cp>He and his team say they used CRISPR to edit 16 embryos, and implanted 11 edited embryos into the wombs of women to attempt to create a viable pregnancy before the twin pregnancy was achieved, according to the Associated Press, which first \u003ca href=\"https://www.apnews.com/4997bb7aa36c45449b488e19ac83e86d\">reported\u003c/a> He’s claims.\u003c/p>\n\u003cp>“No gene was changed except the one to prevent HIV infection,” He says. The twins appear to be healthy, and underwent detailed genetic analysis. “This verified the gene surgery worked safely,” He says.\u003c/p>\n\u003cp>[contextly_sidebar id=”urk3wEQvdunegrn3zKMTD314F18dp2fZ”]Nevertheless, other scientists questioned whether the editing really worked, and argue that it is far too soon for the team to try the experiment.\u003c/p>\n\u003cp>“It is premature at this stage of technology,” wrote \u003ca href=\"https://www.ohsu.edu/people/shoukhrat-mitalipov/2D760207FF014335B07EC30F3818652F\">Shoukhrat Mitalipov\u003c/a>, a scientist at the Oregon Health & Science University in Portland, Ore. Mitalipov was the first scientist to \u003ca href=\"https://www.npr.org/sections/health-shots/2017/08/18/543769759/a-first-look-inside-the-lab-where-scientists-are-editing-dna-in-human-embryos\">report\u003c/a> using CRISPR to successfully edit human embryos, but stopped far short of trying to use them to make babies.\u003c/p>\n\u003cp>Other experts agree.\u003c/p>\n\u003cp>“Although I appreciate the global threat posed by HIV, at this stage, the risks of editing embryos to knock out CCR5 seem to outweigh the potential benefits,” wrote \u003ca href=\"https://www.broadinstitute.org/bios/feng-zhang\">Feng Zhang\u003c/a>, a CRISPR pioneer at MIT. Zhang noted that knocking out the CCR5 gene “will likely render a person much more susceptible for West Nile Virus.”\u003c/p>\n\u003cp>CRISPR enables scientists to make very precise changes in DNA much more easily than ever before. As a result, it’s revolutionizing scientific research and raising high hopes for major breakthroughs, including preventing and treating many diseases.\u003c/p>\n\u003cp>But making changes in human DNA that could be passed down for generations has long been considered off-limits. One reason is that a mistake could introduce a new disease that could be passed down for generations. Another is that it could open the door to “designer babies” — children that are modified for nonmedical reasons, such as to be taller, stronger or smarter.\u003c/p>\n\u003cp>“If it’s true as reported, then it’s an extremely premature and questionable experiment in creating genetically modified children,” agrees \u003ca href=\"http://www.bioethicsinstitute.org/people/jeffrey-kahn-4\">Jeffrey Kahn\u003c/a>, a bioethicist at Johns Hopkins Berman Institute of Bioethics attending the Hong Kong summit.\u003c/p>\n\u003cp>But the development of CRISPR has prompted some scientists to rethink that prohibition for medical purposes. And researchers around the world have been racing to determine how it could be done safely. Many scientists believe it is inevitable, but should be restricted to situations where no alternative is available.\u003c/p>\n\u003cp>“If true, this amounts to unethical and reckless experimentation on human beings, and a grave abuse of human rights,” said \u003ca href=\"https://www.geneticsandsociety.org/user/25\">Marcy Darnovsky\u003c/a>, executive director of the Center for Genetics and Society, a genetic watchdog group.\u003c/p>\n\u003cp>“Throwing open the door to a society of genetic haves and have-nots undermines our chances for a fair and just future,” Darnovsky says.\u003c/p>\n\u003cp>Chinese researcher He acknowledges his work could spark criticism, but defends the step. “I understand my work will be controversial,” he says. “But I believe families need this technology. And I am willing to take the criticism for them.”\u003c/p>\n\u003cp>[ad floatright]\u003c/p>\n\u003cp>\u003cem>Copyright 2018 \u003ca href=\"https://www.npr.org\" target=\"_blank\" rel=\"noopener\">NPR\u003c/a>. \u003c/em>\u003c/p>\n\n","blocks":[],"excerpt":"A scientist says he created the first genetically edited babies using CRISPR to protect them from HIV infection. The move has prompted immediate criticism as premature and reckless.","status":"publish","parent":0,"modified":1704927287,"stats":{"hasAudio":false,"hasVideo":true,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":34,"wordCount":1208},"headData":{"title":"Chinese Scientist Says He's First to Create Genetically Modified Babies Using CRISPR | KQED","description":"A scientist says he created the first genetically edited babies using CRISPR to protect them from HIV infection. The move has prompted immediate criticism as premature and reckless.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":""},"source":"NPR","sourceUrl":"https://www.npr.org/sections/health-shots/2018/11/26/670752865/chinese-scientist-says-hes-first-to-genetically-edit-babies","sticky":false,"nprImageCredit":"Mark Schiefelbein","nprByline":"Rob Stein\u003cbr>\u003cstrong>NPR\u003c/strong>","nprImageAgency":"AP","nprStoryId":"670752865","nprApiLink":"http://api.npr.org/query?id=670752865&apiKey=MDAxOTAwOTE4MDEyMTkxMDAzNjczZDljZA004","nprHtmlLink":"https://www.npr.org/sections/health-shots/2018/11/26/670752865/chinese-scientist-says-hes-first-to-genetically-edit-babies?ft=nprml&f=670752865","nprRetrievedStory":"1","nprPubDate":"Mon, 26 Nov 2018 12:21:00 -0500","nprStoryDate":"Mon, 26 Nov 2018 05:02:00 -0500","nprLastModifiedDate":"Mon, 26 Nov 2018 12:22:14 -0500","nprAudio":"https://ondemand.npr.org/anon.npr-mp3/npr/me/2018/11/20181126_me_scientist_from_china_says_hes_the_first_to_genetically_edit_babies.mp3?orgId=1&topicId=1128&d=222&p=3&story=670752865&ft=nprml&f=670752865","nprAudioM3u":"http://api.npr.org/m3u/1670752866-9d5fbf.m3u?orgId=1&topicId=1128&d=222&p=3&story=670752865&ft=nprml&f=670752865","audioTrackLength":222,"path":"/science/1934916/chinese-scientist-says-hes-first-to-create-genetically-modified-babies-using-crispr","audioUrl":"https://ondemand.npr.org/anon.npr-mp3/npr/me/2018/11/20181126_me_scientist_from_china_says_hes_the_first_to_genetically_edit_babies.mp3?orgId=1&topicId=1128&d=222&p=3&story=670752865&ft=nprml&f=670752865","parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cp>\u003cem>Editor’s note: This story was updated at 11:52 a.m. to add information about an ethics committee investigation into the DNA-editing experiment.\u003c/em>\u003c/p>\n\u003cp>For the first time, a scientist claims to have used a powerful new gene-editing technique to create genetically modified human babies.\u003c/p>\n\u003cp>The scientist, \u003ca href=\"http://www.sustc-genome.org.cn/\">He Jiankui \u003c/a>of the Southern University of Science and Technology in Shenzhen, China, says he used human embryos modified with the gene-editing technique \u003ca href=\"https://www.kqed.org/futureofyou/tag/crispr\">CRISPR\u003c/a> to create twin girls.\u003c/p>\n\u003cp>\u003c/p>\u003cp>\u003c/p>\u003cp>”Two beautiful little Chinese girls name Lulu and Nana came crying into the world as healthy as any other babies a few weeks ago,” He says in a \u003ca href=\"https://www.youtube.com/watch?v=th0vnOmFltc&app=desktop\">video \u003c/a>posted online. “The babies are home now with their mom Grace and their dad Mark.”\u003c/p>\n\u003cp>He says his team performed “gene surgery” on embryos created from their parents’ sperm and eggs to protect the children from the human immunodeficiency virus, \u003ca href=\"https://www.cdc.gov/hiv/basics/\">HIV\u003c/a>, which causes AIDS. The children’s father is HIV-positive.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\u003c/p>\u003cp>\u003cspan class='utils-parseShortcode-shortcodes-__youtubeShortcode__embedYoutube'>\n \u003cspan class='utils-parseShortcode-shortcodes-__youtubeShortcode__embedYoutubeInside'>\n \u003ciframe\n loading='lazy'\n class='utils-parseShortcode-shortcodes-__youtubeShortcode__youtubePlayer'\n type='text/html'\n src='//www.youtube.com/embed/aezxaOn0efE'\n title='//www.youtube.com/embed/aezxaOn0efE'\n allowfullscreen='true'\n style='border:0;'>\u003c/iframe>\n \u003c/span>\n \u003c/span>\u003c/p>\u003cp>\u003cp>“When Lulu and Nana were just a single cell, this surgery removed a doorway through which HIV enter to infect people,” He says in the video, one of several \u003ca href=\"https://www.youtube.com/channel/UCn_Elifynj3LrubPKHXecwQ\">posted online\u003c/a> to justify and explain the work.\u003c/p>\n\u003cp>Because the research has not yet been published in a scientific journal or carefully vetted by other scientists, many researchers and bioethicists remain cautious about the claim.\u003c/p>\n\u003cp>But, if true, many said the move would be historic, comparing it to the birth of \u003ca href=\"https://www.louisejoybrown.com/\">Louise Brown\u003c/a>, the first baby created through in-vitro fertilization, IVF.\u003c/p>\n\u003cp>“This event might be analogous to Louise Brown in 1978,” wrote \u003ca href=\"http://arep.med.harvard.edu/gmc/\">George Church\u003c/a>, a prominent Harvard geneticist, in an email. “Both anecdotal — yet healthy baby girls can have an impact,” Church wrote.\u003c/p>\n\u003cp>Meanwhile, He is now facing \u003ca href=\"http://tech.sina.com.cn/d/f/2018-11-26/doc-ihmutuec3839378.shtml\">investigation\u003c/a> by a local medical ethics board to see whether his experiment broke Chinese laws or regulations.\u003c/p>\n\u003cp>The university where He worked issued a \u003ca href=\"http://sustc.edu.cn/en/info_focus/2871\">statement\u003c/a> that officials were “deeply shocked” by the experiment, which it stressed was conducted elsewhere. He, the statement says, has been on unpaid leave from the university.\u003c/p>\n\u003cp>Church and He are among hundreds of scientists gathering at the \u003ca href=\"http://www.nationalacademies.org/gene-editing/2nd_summit/index.htm\">Second International Summit on Human Gene Editing\u003c/a> in Hong Kong. The summit was organized try to reach a global consensus on whether and how it would be ethical to create genetically modified human beings with CRISPR.\u003c/p>\n\u003cp>The claims by He sparked immediate widespread criticism from attendees at the summit and elsewhere.\u003c/p>\n\u003cp>“This work is a break from the cautious and transparent approach of the global scientific community’s application of CRISPR-Cas9 for human germline editing,” \u003ca href=\"http://doudnalab.org/\">Jennifer Doudna\u003c/a>, a biochemist at the University of California, Berkeley, said in an interview. Doudna helped discover CRISPR and organize the summit.\u003c/p>\n\u003cp>\u003c/p>\u003cp>\u003c/p>\u003cp>”All of us that are here at this conference are struggling to figure out what was done and also whether the process was done properly. We just don’t know yet,” Doudna says.\u003c/p>\n\u003cp>But the claim “really reinforces the urgent need to confine the use of gene-editing in human embryos to settings where there’s a clear unmet medical need and where there’s no alternative viable approach,” says Doudna. She doesn’t think that is the case in this situation.\u003c/p>\n\u003cp>“If this was done to avoid HIV infection, there are alternative ways to prevent infection that are already effective,” Doudna says, such as “washing” the sperm of infected sperm donors to eliminate HIV. “Why would you use this instead of an already established approach?”\u003c/p>\n\u003cp>For their research, He and his colleagues say they used CRISPR to make changes in one-day old embryos in a gene called \u003ca href=\"https://ghr.nlm.nih.gov/gene/CCR5\">CCR5\u003c/a>. The CCR5 gene enables HIV to enter and infect immune system cells. Scientists have long searched for ways to block this pathway to protect people from HIV.\u003c/p>\n\u003cp>He and his team say they used CRISPR to edit 16 embryos, and implanted 11 edited embryos into the wombs of women to attempt to create a viable pregnancy before the twin pregnancy was achieved, according to the Associated Press, which first \u003ca href=\"https://www.apnews.com/4997bb7aa36c45449b488e19ac83e86d\">reported\u003c/a> He’s claims.\u003c/p>\n\u003cp>“No gene was changed except the one to prevent HIV infection,” He says. The twins appear to be healthy, and underwent detailed genetic analysis. “This verified the gene surgery worked safely,” He says.\u003c/p>\n\u003cp>\u003c/p>\u003cp>\u003c/p>\u003cp>Nevertheless, other scientists questioned whether the editing really worked, and argue that it is far too soon for the team to try the experiment.\u003c/p>\n\u003cp>“It is premature at this stage of technology,” wrote \u003ca href=\"https://www.ohsu.edu/people/shoukhrat-mitalipov/2D760207FF014335B07EC30F3818652F\">Shoukhrat Mitalipov\u003c/a>, a scientist at the Oregon Health & Science University in Portland, Ore. Mitalipov was the first scientist to \u003ca href=\"https://www.npr.org/sections/health-shots/2017/08/18/543769759/a-first-look-inside-the-lab-where-scientists-are-editing-dna-in-human-embryos\">report\u003c/a> using CRISPR to successfully edit human embryos, but stopped far short of trying to use them to make babies.\u003c/p>\n\u003cp>Other experts agree.\u003c/p>\n\u003cp>“Although I appreciate the global threat posed by HIV, at this stage, the risks of editing embryos to knock out CCR5 seem to outweigh the potential benefits,” wrote \u003ca href=\"https://www.broadinstitute.org/bios/feng-zhang\">Feng Zhang\u003c/a>, a CRISPR pioneer at MIT. Zhang noted that knocking out the CCR5 gene “will likely render a person much more susceptible for West Nile Virus.”\u003c/p>\n\u003cp>CRISPR enables scientists to make very precise changes in DNA much more easily than ever before. As a result, it’s revolutionizing scientific research and raising high hopes for major breakthroughs, including preventing and treating many diseases.\u003c/p>\n\u003cp>But making changes in human DNA that could be passed down for generations has long been considered off-limits. One reason is that a mistake could introduce a new disease that could be passed down for generations. Another is that it could open the door to “designer babies” — children that are modified for nonmedical reasons, such as to be taller, stronger or smarter.\u003c/p>\n\u003cp>“If it’s true as reported, then it’s an extremely premature and questionable experiment in creating genetically modified children,” agrees \u003ca href=\"http://www.bioethicsinstitute.org/people/jeffrey-kahn-4\">Jeffrey Kahn\u003c/a>, a bioethicist at Johns Hopkins Berman Institute of Bioethics attending the Hong Kong summit.\u003c/p>\n\u003cp>But the development of CRISPR has prompted some scientists to rethink that prohibition for medical purposes. And researchers around the world have been racing to determine how it could be done safely. Many scientists believe it is inevitable, but should be restricted to situations where no alternative is available.\u003c/p>\n\u003cp>“If true, this amounts to unethical and reckless experimentation on human beings, and a grave abuse of human rights,” said \u003ca href=\"https://www.geneticsandsociety.org/user/25\">Marcy Darnovsky\u003c/a>, executive director of the Center for Genetics and Society, a genetic watchdog group.\u003c/p>\n\u003cp>“Throwing open the door to a society of genetic haves and have-nots undermines our chances for a fair and just future,” Darnovsky says.\u003c/p>\n\u003cp>Chinese researcher He acknowledges his work could spark criticism, but defends the step. “I understand my work will be controversial,” he says. “But I believe families need this technology. And I am willing to take the criticism for them.”\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"floatright"},"numeric":["floatright"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>\u003cem>Copyright 2018 \u003ca href=\"https://www.npr.org\" target=\"_blank\" rel=\"noopener\">NPR\u003c/a>. \u003c/em>\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/science/1934916/chinese-scientist-says-hes-first-to-create-genetically-modified-babies-using-crispr","authors":["byline_science_1934916"],"categories":["science_3151","science_39","science_3424","science_40"],"tags":["science_1287","science_660"],"featImg":"science_1935025","label":"source_science_1934916"},"science_8108":{"type":"posts","id":"science_8108","meta":{"index":"posts_1591205157","site":"science","id":"8108","score":null,"sort":[1378738857000]},"guestAuthors":[],"slug":"molecular-scissors-may-help-potentially-cure-aids-in-the-future","title":"Molecular Scissors May Help Potentially Cure AIDS in the Future","publishDate":1378738857,"format":"aside","headTitle":"Molecular Scissors May Help Potentially Cure AIDS in the Future | KQED","labelTerm":{"site":"science"},"content":"\u003cfigure id=\"attachment_8111\" class=\"wp-caption aligncenter\" style=\"max-width: 637px\">\u003ca href=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2013/09/AIDSquilt.jpg\" rel=\"attachment wp-att-8111\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-8111\" src=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2013/09/AIDSquilt.jpg\" alt=\"We will know in a few years if a new treatment will end up being a cure for AIDS. This image of the AIDS quilt is courtesy of Wikimedia Commons.\" width=\"637\" height=\"351\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">We will know in a few years if a new treatment will end up being a cure for AIDS. This image of the AIDS quilt is courtesy of \u003ca href=\"http://commons.wikimedia.org/wiki/File:AIDS_Quilt_at_2012_International_AIDS_Conference.JPG\">Wikimedia Commons\u003c/a>.\u003c/figcaption>\u003c/figure>\n\u003cp>Ever since AIDS emerged as a deadly disease in the early 1980’s, scientists have been looking for a cure. And now, using a very precise set of DNA scissors, they may finally be taking baby steps towards one.\u003c/p>\n\u003cp>The new hope rests on the old observation that a few people are highly resistant or even immune to HIV, the virus that causes AIDS. These people can live a high-risk lifestyle that results in multiple exposures to the virus and still never end up with the disease.\u003c/p>\n\u003cp>When scientists looked at these people’s DNA, they found that many of them shared a specific genetic mutation called \u003ca href=\"http://genetics.thetech.org/ask/ask336\">CCR5 delta32\u003c/a>. This mutation inactivates the CCR5 gene which means these people make no CCR5 protein. This lack of CCR5 protein makes these folks highly resistant to getting AIDS because the most virulent form of the virus, HIV-1, needs it to get into blood cells. No infection means no AIDS.\u003c/p>\n\u003cp>While this is interesting and obviously a boon to the small minority of people with this mutation, it doesn’t seem like it would be very useful for people already infected with HIV. And yet it has turned out to be incredibly useful.\u003c/p>\n\u003cp>Learning about this mutation pointed scientists towards a new class of drugs, \u003ca href=\"http://en.wikipedia.org/wiki/CCR5_receptor_antagonist\">CCR5 receptor antagonists\u003c/a>. These drugs block the action of the CCR5 protein making it very difficult for HIV-1 to enter the patient’s blood cells. At least one of these, Selzentry, is currently being used to treat some cases of HIV.\u003c/p>\n\u003cp>[ad fullwidth]\u003c/p>\n\u003cp>And this isn’t even the most exciting use of this discovery. Scientists in Germany actually used this knowledge to \u003ca href=\"http://science.kqed.org/quest/2008/11/24/curing-aids-with-a-bone-marrow-transplant/\">cure a man of his AIDS\u003c/a>!\u003c/p>\n\u003cfigure id=\"attachment_8127\" class=\"wp-caption alignright\" style=\"max-width: 250px\">\u003ca href=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2013/09/ccr5.jpg\" rel=\"attachment wp-att-8127\">\u003cimg loading=\"lazy\" decoding=\"async\" src=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2013/09/ccr5.jpg\" alt=\"The molecule in yellow, CCR5, may be the key to an eventual cure for AIDS. Image courtesy of Wikimedia Commons.\" width=\"250\" height=\"248\" class=\"size-full wp-image-8127\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">The molecule in yellow, CCR5, may be the key to an eventual cure for AIDS. Image courtesy of \u003ca href=\"http://commons.wikimedia.org/wiki/File:CCR5_receptor%2Bmembrane.png\">Wikimedia Commons\u003c/a>.\u003c/figcaption>\u003c/figure>\n\u003cp>Back in 2007, an AIDS patient in Berlin Germany was told he would need a bone marrow transplant to treat his newly diagnosed leukemia. He and his doctor decided to seek out a donor who had the CCR5 delta 32 mutation. The hope was that this bone marrow transplant would treat both of his diseases at once. Their hope was realized: his leukemia went into remission and his viral load became undetectable. This bone marrow transplant cured his AIDS.\u003c/p>\n\u003cp>Bone marrow transplants replace a patient’s blood stem cells with the donor’s. What this means in this case is that the AIDS patient now had the donor’s blood cells coursing through his veins and these new blood cells lacked the CCR5 protein. Any HIV-1 he had in his system now had no way of making copies of itself which is why his viral load fell to the undetectable levels where they remain to this day.\u003c/p>\n\u003cp>Unfortunately, scientists can’t do this for everyone with AIDS. Not only is the CCR5 delta 32 mutation rare enough that it would be impossible to find donor matches for all or even most AIDS patient, but bone marrow transplants are also dangerous, expensive treatments with a high mortality rate. No, we need a different way to use this mutation to help cure other AIDS patients.\u003c/p>\n\u003cp>One way would be to engineer the mutation into a patient’s blood cells. Now we could avoid having to find a donor.\u003c/p>\n\u003cp>This is just what the folks at Sangamo Biosciences are trying to do. With the help of a \u003ca href=\"http://science.kqed.org/quest/audio/a-unique-hiv-case-inspires-new-research/\">team of academic collaborators\u003c/a> and money from \u003ca href=\"http://www.cirm.ca.gov/\">California Stem Cell Bond\u003c/a>, they have come up with a product called \u003ca href=\"http://www.sangamo.com/pipeline/sb-728.html\">SB-728\u003c/a> that can specifically inactivate the CCR5 gene in human cells. This treatment has even made it into clinical trials where so far the results appear to be encouraging (although \u003ca href=\"http://bir-llc.com/sb-728-t/\">not everyone agrees\u003c/a>).\u003c/p>\n\u003cp>If this approach works, it would be a game changer for AIDS. The disease would go from being manageable to being functionally cured. And that isn’t all. There are other diseases that could be treated similarly. Success here could translate to a whole new way to get at other intractable diseases.\u003c/p>\n\u003cp>This is all very exciting, but I want to caution against getting our hopes up just yet. This specific treatment could still fail in ongoing clinical trials or even turn out to not be a permanent cure. But still, because of the Berlin patient, we know that if we can inactivate the CCR5 gene in a patient’s blood cells, we can cure his or her AIDS. So even if this approach fails, there may be other ways to kill this gene.\u003c/p>\n\u003cp>\u003cstrong>Molecular Scissor Science\u003c/strong>\u003c/p>\n\u003cfigure id=\"attachment_8130\" class=\"wp-caption alignright\" style=\"max-width: 250px\">\u003ca href=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2013/09/MolecularScissors.jpg\" rel=\"attachment wp-att-8130\">\u003cimg loading=\"lazy\" decoding=\"async\" src=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2013/09/MolecularScissors.jpg\" alt=\"Image courtesy of Dr. Stacey Wirt, Stanford University.\" width=\"250\" height=\"253\" class=\"size-full wp-image-8130\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Image courtesy of Dr. Stacey Wirt, Stanford University.\u003c/figcaption>\u003c/figure>\n\u003cp>The science behind this approach is very cool. The basic idea is to create a pair of molecular scissors that will cut human DNA only at the CCR5 gene. Once cut, our cells will wreck the gene in the process of repairing the DNA. Remember, a broken CCR5 gene means no CCR5 protein which means no HIV-1 infection.\u003c/p>\n\u003cp>The scissors part is easy. There are lots of enzymes whose job it is to cut DNA. The most famous are the restriction endonucleases from bacteria that serve as a part of their primitive immune system (they chop up invading viruses). In fact, molecular biology is built on these enzymes.\u003c/p>\n\u003cp>At the time scientists at Sangamo started working on this approach, there were no natural enzymes specific enough for their purposes. The enzymes known at this time would cut human DNA at thousands of different places which would obviously be catastrophic. The patient would not survive such treatment.\u003cbr>\nSo the scientists needed to come up with a way to make these scissors only cut at the spot they wanted. There are a number of ways to do this but the scientists at Sangamo focused on natural DNA binders called zinc finger proteins.\u003c/p>\n\u003cp>The first step was to figure out how these zinc finger proteins recognize specific DNA sequences. With a lot of work, they came to understand this well enough that they could now create zinc fingers that recognize any three bases they were interested in. So they could whip up one that recognized ATG and another that could recognize CCC and so on.\u003c/p>\n\u003cp>Three base pairs isn’t enough and in fact, is worse than any of the naturally available enzymes. To get at the 18-24 base pair recognition they needed, they decided to string together multiple zinc fingers. Now they had the specificity they needed. (I have simplified this mightily but it is the basic idea…click \u003ca href=\"http://www.zincfingers.org/default2.htm\">here \u003c/a>if you want to go deeper.)\u003c/p>\n\u003cp>So the scientists whipped up a protein that could specifically recognize the CCR5 gene and attached the unfortunately named Fok1 as its scissors. This protein cuts the CCR5 gene in cells in the lab and in clinical trials. So far so good.\u003c/p>\n\u003cp>We need to wait to see what happens, but these trials are definitely something we need to keep our eyes on. They may not only lead to a functional cure for AIDS, but they could also open up a whole new way to treat diseases.\u003c/p>\n\u003cp>http://www.youtube.com/watch?v=zDkUFzZoQAs\u003c/p>\n\u003cp>[ad floatright]\u003c/p>\n\u003cp>\u003cem>A very nice explanation of zinc finger nucleases and a second type of scissors, TALENs.\u003c/em>\u003c/p>\n\n","blocks":[],"excerpt":"Ever since AIDS emerged as a deadly disease in the early 1980’s, scientists have been looking for a cure. And now, using a very precise set of DNA scissors, they may finally be taking baby steps towards one.","status":"publish","parent":0,"modified":1704935098,"stats":{"hasAudio":false,"hasVideo":false,"hasChartOrMap":false,"iframeSrcs":[],"hasGoogleForm":false,"hasGallery":false,"hasHearkenModule":false,"hasPolis":false,"paragraphCount":24,"wordCount":1248},"headData":{"title":"Molecular Scissors May Help Potentially Cure AIDS in the Future | KQED","description":"Ever since AIDS emerged as a deadly disease in the early 1980’s, scientists have been looking for a cure. And now, using a very precise set of DNA scissors, they may finally be taking baby steps towards one.","ogTitle":"","ogDescription":"","ogImgId":"","twTitle":"","twDescription":"","twImgId":""},"sticky":false,"path":"/science/8108/molecular-scissors-may-help-potentially-cure-aids-in-the-future","audioTrackLength":null,"parsedContent":[{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003cfigure id=\"attachment_8111\" class=\"wp-caption aligncenter\" style=\"max-width: 637px\">\u003ca href=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2013/09/AIDSquilt.jpg\" rel=\"attachment wp-att-8111\">\u003cimg loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-8111\" src=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2013/09/AIDSquilt.jpg\" alt=\"We will know in a few years if a new treatment will end up being a cure for AIDS. This image of the AIDS quilt is courtesy of Wikimedia Commons.\" width=\"637\" height=\"351\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">We will know in a few years if a new treatment will end up being a cure for AIDS. This image of the AIDS quilt is courtesy of \u003ca href=\"http://commons.wikimedia.org/wiki/File:AIDS_Quilt_at_2012_International_AIDS_Conference.JPG\">Wikimedia Commons\u003c/a>.\u003c/figcaption>\u003c/figure>\n\u003cp>Ever since AIDS emerged as a deadly disease in the early 1980’s, scientists have been looking for a cure. And now, using a very precise set of DNA scissors, they may finally be taking baby steps towards one.\u003c/p>\n\u003cp>The new hope rests on the old observation that a few people are highly resistant or even immune to HIV, the virus that causes AIDS. These people can live a high-risk lifestyle that results in multiple exposures to the virus and still never end up with the disease.\u003c/p>\n\u003cp>When scientists looked at these people’s DNA, they found that many of them shared a specific genetic mutation called \u003ca href=\"http://genetics.thetech.org/ask/ask336\">CCR5 delta32\u003c/a>. This mutation inactivates the CCR5 gene which means these people make no CCR5 protein. This lack of CCR5 protein makes these folks highly resistant to getting AIDS because the most virulent form of the virus, HIV-1, needs it to get into blood cells. No infection means no AIDS.\u003c/p>\n\u003cp>While this is interesting and obviously a boon to the small minority of people with this mutation, it doesn’t seem like it would be very useful for people already infected with HIV. And yet it has turned out to be incredibly useful.\u003c/p>\n\u003cp>Learning about this mutation pointed scientists towards a new class of drugs, \u003ca href=\"http://en.wikipedia.org/wiki/CCR5_receptor_antagonist\">CCR5 receptor antagonists\u003c/a>. These drugs block the action of the CCR5 protein making it very difficult for HIV-1 to enter the patient’s blood cells. At least one of these, Selzentry, is currently being used to treat some cases of HIV.\u003c/p>\n\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"fullwidth"},"numeric":["fullwidth"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>And this isn’t even the most exciting use of this discovery. Scientists in Germany actually used this knowledge to \u003ca href=\"http://science.kqed.org/quest/2008/11/24/curing-aids-with-a-bone-marrow-transplant/\">cure a man of his AIDS\u003c/a>!\u003c/p>\n\u003cfigure id=\"attachment_8127\" class=\"wp-caption alignright\" style=\"max-width: 250px\">\u003ca href=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2013/09/ccr5.jpg\" rel=\"attachment wp-att-8127\">\u003cimg loading=\"lazy\" decoding=\"async\" src=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2013/09/ccr5.jpg\" alt=\"The molecule in yellow, CCR5, may be the key to an eventual cure for AIDS. Image courtesy of Wikimedia Commons.\" width=\"250\" height=\"248\" class=\"size-full wp-image-8127\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">The molecule in yellow, CCR5, may be the key to an eventual cure for AIDS. Image courtesy of \u003ca href=\"http://commons.wikimedia.org/wiki/File:CCR5_receptor%2Bmembrane.png\">Wikimedia Commons\u003c/a>.\u003c/figcaption>\u003c/figure>\n\u003cp>Back in 2007, an AIDS patient in Berlin Germany was told he would need a bone marrow transplant to treat his newly diagnosed leukemia. He and his doctor decided to seek out a donor who had the CCR5 delta 32 mutation. The hope was that this bone marrow transplant would treat both of his diseases at once. Their hope was realized: his leukemia went into remission and his viral load became undetectable. This bone marrow transplant cured his AIDS.\u003c/p>\n\u003cp>Bone marrow transplants replace a patient’s blood stem cells with the donor’s. What this means in this case is that the AIDS patient now had the donor’s blood cells coursing through his veins and these new blood cells lacked the CCR5 protein. Any HIV-1 he had in his system now had no way of making copies of itself which is why his viral load fell to the undetectable levels where they remain to this day.\u003c/p>\n\u003cp>Unfortunately, scientists can’t do this for everyone with AIDS. Not only is the CCR5 delta 32 mutation rare enough that it would be impossible to find donor matches for all or even most AIDS patient, but bone marrow transplants are also dangerous, expensive treatments with a high mortality rate. No, we need a different way to use this mutation to help cure other AIDS patients.\u003c/p>\n\u003cp>One way would be to engineer the mutation into a patient’s blood cells. Now we could avoid having to find a donor.\u003c/p>\n\u003cp>This is just what the folks at Sangamo Biosciences are trying to do. With the help of a \u003ca href=\"http://science.kqed.org/quest/audio/a-unique-hiv-case-inspires-new-research/\">team of academic collaborators\u003c/a> and money from \u003ca href=\"http://www.cirm.ca.gov/\">California Stem Cell Bond\u003c/a>, they have come up with a product called \u003ca href=\"http://www.sangamo.com/pipeline/sb-728.html\">SB-728\u003c/a> that can specifically inactivate the CCR5 gene in human cells. This treatment has even made it into clinical trials where so far the results appear to be encouraging (although \u003ca href=\"http://bir-llc.com/sb-728-t/\">not everyone agrees\u003c/a>).\u003c/p>\n\u003cp>If this approach works, it would be a game changer for AIDS. The disease would go from being manageable to being functionally cured. And that isn’t all. There are other diseases that could be treated similarly. Success here could translate to a whole new way to get at other intractable diseases.\u003c/p>\n\u003cp>This is all very exciting, but I want to caution against getting our hopes up just yet. This specific treatment could still fail in ongoing clinical trials or even turn out to not be a permanent cure. But still, because of the Berlin patient, we know that if we can inactivate the CCR5 gene in a patient’s blood cells, we can cure his or her AIDS. So even if this approach fails, there may be other ways to kill this gene.\u003c/p>\n\u003cp>\u003cstrong>Molecular Scissor Science\u003c/strong>\u003c/p>\n\u003cfigure id=\"attachment_8130\" class=\"wp-caption alignright\" style=\"max-width: 250px\">\u003ca href=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2013/09/MolecularScissors.jpg\" rel=\"attachment wp-att-8130\">\u003cimg loading=\"lazy\" decoding=\"async\" src=\"http://ww2.kqed.org/science/wp-content/uploads/sites/35/2013/09/MolecularScissors.jpg\" alt=\"Image courtesy of Dr. Stacey Wirt, Stanford University.\" width=\"250\" height=\"253\" class=\"size-full wp-image-8130\">\u003c/a>\u003cfigcaption class=\"wp-caption-text\">Image courtesy of Dr. Stacey Wirt, Stanford University.\u003c/figcaption>\u003c/figure>\n\u003cp>The science behind this approach is very cool. The basic idea is to create a pair of molecular scissors that will cut human DNA only at the CCR5 gene. Once cut, our cells will wreck the gene in the process of repairing the DNA. Remember, a broken CCR5 gene means no CCR5 protein which means no HIV-1 infection.\u003c/p>\n\u003cp>The scissors part is easy. There are lots of enzymes whose job it is to cut DNA. The most famous are the restriction endonucleases from bacteria that serve as a part of their primitive immune system (they chop up invading viruses). In fact, molecular biology is built on these enzymes.\u003c/p>\n\u003cp>At the time scientists at Sangamo started working on this approach, there were no natural enzymes specific enough for their purposes. The enzymes known at this time would cut human DNA at thousands of different places which would obviously be catastrophic. The patient would not survive such treatment.\u003cbr>\nSo the scientists needed to come up with a way to make these scissors only cut at the spot they wanted. There are a number of ways to do this but the scientists at Sangamo focused on natural DNA binders called zinc finger proteins.\u003c/p>\n\u003cp>The first step was to figure out how these zinc finger proteins recognize specific DNA sequences. With a lot of work, they came to understand this well enough that they could now create zinc fingers that recognize any three bases they were interested in. So they could whip up one that recognized ATG and another that could recognize CCC and so on.\u003c/p>\n\u003cp>Three base pairs isn’t enough and in fact, is worse than any of the naturally available enzymes. To get at the 18-24 base pair recognition they needed, they decided to string together multiple zinc fingers. Now they had the specificity they needed. (I have simplified this mightily but it is the basic idea…click \u003ca href=\"http://www.zincfingers.org/default2.htm\">here \u003c/a>if you want to go deeper.)\u003c/p>\n\u003cp>So the scientists whipped up a protein that could specifically recognize the CCR5 gene and attached the unfortunately named Fok1 as its scissors. This protein cuts the CCR5 gene in cells in the lab and in clinical trials. So far so good.\u003c/p>\n\u003cp>We need to wait to see what happens, but these trials are definitely something we need to keep our eyes on. They may not only lead to a functional cure for AIDS, but they could also open up a whole new way to treat diseases.\u003c/p>\u003c/p>\u003cp>\u003cspan class='utils-parseShortcode-shortcodes-__youtubeShortcode__embedYoutube'>\n \u003cspan class='utils-parseShortcode-shortcodes-__youtubeShortcode__embedYoutubeInside'>\n \u003ciframe\n loading='lazy'\n class='utils-parseShortcode-shortcodes-__youtubeShortcode__youtubePlayer'\n type='text/html'\n src='//www.youtube.com/embed/zDkUFzZoQAs'\n title='//www.youtube.com/embed/zDkUFzZoQAs'\n allowfullscreen='true'\n style='border:0;'>\u003c/iframe>\n \u003c/span>\n \u003c/span>\u003c/p>\u003cp>\u003cp>\u003c/p>\u003c/div>","attributes":{"named":{},"numeric":[]}},{"type":"component","content":"","name":"ad","attributes":{"named":{"label":"floatright"},"numeric":["floatright"]}},{"type":"contentString","content":"\u003cdiv class=\"post-body\">\u003cp>\u003c/p>\n\u003cp>\u003cem>A very nice explanation of zinc finger nucleases and a second type of scissors, TALENs.\u003c/em>\u003c/p>\n\n\u003c/div>\u003c/p>","attributes":{"named":{},"numeric":[]}}],"link":"/science/8108/molecular-scissors-may-help-potentially-cure-aids-in-the-future","authors":["6177"],"categories":["science_30","science_39"],"tags":["science_664","science_305","science_660"],"featImg":"science_8111","label":"science"}},"programsReducer":{"possible":{"id":"possible","title":"Possible","info":"Possible is hosted by entrepreneur Reid Hoffman and writer Aria Finger. Together in Possible, Hoffman and Finger lead enlightening discussions about building a brighter collective future. The show features interviews with visionary guests like Trevor Noah, Sam Altman and Janette Sadik-Khan. Possible paints an optimistic portrait of the world we can create through science, policy, business, art and our shared humanity. It asks: What if everything goes right for once? How can we get there? Each episode also includes a short fiction story generated by advanced AI GPT-4, serving as a thought-provoking springboard to speculate how humanity could leverage technology for good.","airtime":"SUN 2pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Possible-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.possible.fm/","meta":{"site":"news","source":"Possible"},"link":"/radio/program/possible","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/possible/id1677184070","spotify":"https://open.spotify.com/show/730YpdUSNlMyPQwNnyjp4k"}},"1a":{"id":"1a","title":"1A","info":"1A is home to the national conversation. 1A brings on great guests and frames the best debate in ways that make you think, share and engage.","airtime":"MON-THU 11pm-12am","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/1a.jpg","officialWebsiteLink":"https://the1a.org/","meta":{"site":"news","source":"npr"},"link":"/radio/program/1a","subscribe":{"npr":"https://rpb3r.app.goo.gl/RBrW","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=1188724250&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/1A-p947376/","rss":"https://feeds.npr.org/510316/podcast.xml"}},"all-things-considered":{"id":"all-things-considered","title":"All Things Considered","info":"Every weekday, \u003cem>All Things Considered\u003c/em> hosts Robert Siegel, Audie Cornish, Ari Shapiro, and Kelly McEvers present the program's trademark mix of news, interviews, commentaries, reviews, and offbeat features. Michel Martin hosts on the weekends.","airtime":"MON-FRI 1pm-2pm, 4:30pm-6:30pm\u003cbr />SAT-SUN 5pm-6pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/All-Things-Considered-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.npr.org/programs/all-things-considered/","meta":{"site":"news","source":"npr"},"link":"/radio/program/all-things-considered"},"american-suburb-podcast":{"id":"american-suburb-podcast","title":"American Suburb: The Podcast","tagline":"The flip side of gentrification, told through one town","info":"Gentrification is changing cities across America, forcing people from neighborhoods they have long called home. Call them the displaced. Now those priced out of the Bay Area are looking for a better life in an unlikely place. American Suburb follows this migration to one California town along the Delta, 45 miles from San Francisco. But is this once sleepy suburb ready for them?","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/American-Suburb-Podcast-Tile-703x703-1.jpg","officialWebsiteLink":"/news/series/american-suburb-podcast","meta":{"site":"news","source":"kqed","order":"13"},"link":"/news/series/american-suburb-podcast/","subscribe":{"npr":"https://rpb3r.app.goo.gl/RBrW","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?mt=2&id=1287748328","tuneIn":"https://tunein.com/radio/American-Suburb-p1086805/","rss":"https://ww2.kqed.org/news/series/american-suburb-podcast/feed/podcast","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkMzMDExODgxNjA5"}},"baycurious":{"id":"baycurious","title":"Bay Curious","tagline":"Exploring the Bay Area, one question at a time","info":"KQED’s new podcast, Bay Curious, gets to the bottom of the mysteries — both profound and peculiar — that give the Bay Area its unique identity. And we’ll do it with your help! You ask the questions. You decide what Bay Curious investigates. And you join us on the journey to find the answers.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Bay-Curious-Podcast-Tile-703x703-1.jpg","imageAlt":"\"KQED Bay Curious","officialWebsiteLink":"/news/series/baycurious","meta":{"site":"news","source":"kqed","order":"4"},"link":"/podcasts/baycurious","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/bay-curious/id1172473406","npr":"https://www.npr.org/podcasts/500557090/bay-curious","rss":"https://ww2.kqed.org/news/category/bay-curious-podcast/feed/podcast","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93dzIua3FlZC5vcmcvbmV3cy9jYXRlZ29yeS9iYXktY3VyaW91cy1wb2RjYXN0L2ZlZWQvcG9kY2FzdA","stitcher":"https://www.stitcher.com/podcast/kqed/bay-curious","spotify":"https://open.spotify.com/show/6O76IdmhixfijmhTZLIJ8k"}},"bbc-world-service":{"id":"bbc-world-service","title":"BBC World Service","info":"The day's top stories from BBC News compiled twice daily in the week, once at weekends.","airtime":"MON-FRI 9pm-10pm, TUE-FRI 1am-2am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/BBC-World-Service-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.bbc.co.uk/sounds/play/live:bbc_world_service","meta":{"site":"news","source":"BBC World Service"},"link":"/radio/program/bbc-world-service","subscribe":{"apple":"https://itunes.apple.com/us/podcast/global-news-podcast/id135067274?mt=2","tuneIn":"https://tunein.com/radio/BBC-World-Service-p455581/","rss":"https://podcasts.files.bbci.co.uk/p02nq0gn.rss"}},"code-switch-life-kit":{"id":"code-switch-life-kit","title":"Code Switch / Life Kit","info":"\u003cem>Code Switch\u003c/em>, which listeners will hear in the first part of the hour, has fearless and much-needed conversations about race. Hosted by journalists of color, the show tackles the subject of race head-on, exploring how it impacts every part of society — from politics and pop culture to history, sports and more.\u003cbr />\u003cbr />\u003cem>Life Kit\u003c/em>, which will be in the second part of the hour, guides you through spaces and feelings no one prepares you for — from finances to mental health, from workplace microaggressions to imposter syndrome, from relationships to parenting. The show features experts with real world experience and shares their knowledge. Because everyone needs a little help being human.\u003cbr />\u003cbr />\u003ca href=\"https://www.npr.org/podcasts/510312/codeswitch\">\u003cem>Code Switch\u003c/em> offical site and podcast\u003c/a>\u003cbr />\u003ca href=\"https://www.npr.org/lifekit\">\u003cem>Life Kit\u003c/em> offical site and podcast\u003c/a>\u003cbr />","airtime":"SUN 9pm-10pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Code-Switch-Life-Kit-Podcast-Tile-360x360-1.jpg","meta":{"site":"radio","source":"npr"},"link":"/radio/program/code-switch-life-kit","subscribe":{"apple":"https://podcasts.apple.com/podcast/1112190608?mt=2&at=11l79Y&ct=nprdirectory","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93d3cubnByLm9yZy9yc3MvcG9kY2FzdC5waHA_aWQ9NTEwMzEy","spotify":"https://open.spotify.com/show/3bExJ9JQpkwNhoHvaIIuyV","rss":"https://feeds.npr.org/510312/podcast.xml"}},"commonwealth-club":{"id":"commonwealth-club","title":"Commonwealth Club of California Podcast","info":"The Commonwealth Club of California is the nation's oldest and largest public affairs forum. As a non-partisan forum, The Club brings to the public airwaves diverse viewpoints on important topics. The Club's weekly radio broadcast - the oldest in the U.S., dating back to 1924 - is carried across the nation on public radio stations and is now podcasting. Our website archive features audio of our recent programs, as well as selected speeches from our long and distinguished history. This podcast feed is usually updated twice a week and is always un-edited.","airtime":"THU 10pm, FRI 1am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Commonwealth-Club-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.commonwealthclub.org/podcasts","meta":{"site":"news","source":"Commonwealth Club of California"},"link":"/radio/program/commonwealth-club","subscribe":{"apple":"https://itunes.apple.com/us/podcast/commonwealth-club-of-california-podcast/id976334034?mt=2","google":"https://podcasts.google.com/feed/aHR0cDovL3d3dy5jb21tb253ZWFsdGhjbHViLm9yZy9hdWRpby9wb2RjYXN0L3dlZWtseS54bWw","tuneIn":"https://tunein.com/radio/Commonwealth-Club-of-California-p1060/"}},"considerthis":{"id":"considerthis","title":"Consider This","tagline":"Make sense of the day","info":"Make sense of the day. Every weekday afternoon, Consider This helps you consider the major stories of the day in less than 15 minutes, featuring the reporting and storytelling resources of NPR. Plus, KQED’s Bianca Taylor brings you the local KQED news you need to know.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Consider-This-Podcast-Tile-703x703-1.jpg","imageAlt":"Consider This from NPR and KQED","officialWebsiteLink":"/podcasts/considerthis","meta":{"site":"news","source":"kqed","order":"7"},"link":"/podcasts/considerthis","subscribe":{"apple":"https://podcasts.apple.com/podcast/id1503226625?mt=2&at=11l79Y&ct=nprdirectory","npr":"https://rpb3r.app.goo.gl/coronavirusdaily","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5ucHIub3JnLzUxMDM1NS9wb2RjYXN0LnhtbA","spotify":"https://open.spotify.com/show/3Z6JdCS2d0eFEpXHKI6WqH"}},"forum":{"id":"forum","title":"Forum","tagline":"The conversation starts here","info":"KQED’s live call-in program discussing local, state, national and international issues, as well as in-depth interviews.","airtime":"MON-FRI 9am-11am, 10pm-11pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Forum-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED Forum with Mina Kim and Alexis Madrigal","officialWebsiteLink":"/forum","meta":{"site":"news","source":"kqed","order":"8"},"link":"/forum","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/kqeds-forum/id73329719","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM5NTU3MzgxNjMz","npr":"https://www.npr.org/podcasts/432307980/forum","stitcher":"https://www.stitcher.com/podcast/kqedfm-kqeds-forum-podcast","rss":"https://feeds.megaphone.fm/KQINC9557381633"}},"freakonomics-radio":{"id":"freakonomics-radio","title":"Freakonomics Radio","info":"Freakonomics Radio is a one-hour award-winning podcast and public-radio project hosted by Stephen Dubner, with co-author Steve Levitt as a regular guest. It is produced in partnership with WNYC.","imageSrc":"https://ww2.kqed.org/news/wp-content/uploads/sites/10/2018/05/freakonomicsRadio.png","officialWebsiteLink":"http://freakonomics.com/","airtime":"SUN 1am-2am, SAT 3pm-4pm","meta":{"site":"radio","source":"WNYC"},"link":"/radio/program/freakonomics-radio","subscribe":{"npr":"https://rpb3r.app.goo.gl/4s8b","apple":"https://itunes.apple.com/us/podcast/freakonomics-radio/id354668519","tuneIn":"https://tunein.com/podcasts/WNYC-Podcasts/Freakonomics-Radio-p272293/","rss":"https://feeds.feedburner.com/freakonomicsradio"}},"fresh-air":{"id":"fresh-air","title":"Fresh Air","info":"Hosted by Terry Gross, \u003cem>Fresh Air from WHYY\u003c/em> is the Peabody Award-winning weekday magazine of contemporary arts and issues. One of public radio's most popular programs, Fresh Air features intimate conversations with today's biggest luminaries.","airtime":"MON-FRI 7pm-8pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Fresh-Air-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.npr.org/programs/fresh-air/","meta":{"site":"radio","source":"npr"},"link":"/radio/program/fresh-air","subscribe":{"npr":"https://rpb3r.app.goo.gl/4s8b","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=214089682&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/Fresh-Air-p17/","rss":"https://feeds.npr.org/381444908/podcast.xml"}},"here-and-now":{"id":"here-and-now","title":"Here & Now","info":"A live production of NPR and WBUR Boston, in collaboration with stations across the country, Here & Now reflects the fluid world of news as it's happening in the middle of the day, with timely, in-depth news, interviews and conversation. Hosted by Robin Young, Jeremy Hobson and Tonya Mosley.","airtime":"MON-THU 11am-12pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Here-And-Now-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"http://www.wbur.org/hereandnow","meta":{"site":"news","source":"npr"},"link":"/radio/program/here-and-now","subsdcribe":{"apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?mt=2&id=426698661","tuneIn":"https://tunein.com/radio/Here--Now-p211/","rss":"https://feeds.npr.org/510051/podcast.xml"}},"how-i-built-this":{"id":"how-i-built-this","title":"How I Built This with Guy Raz","info":"Guy Raz dives into the stories behind some of the world's best known companies. How I Built This weaves a narrative journey about innovators, entrepreneurs and idealists—and the movements they built.","imageSrc":"https://ww2.kqed.org/news/wp-content/uploads/sites/10/2018/05/howIBuiltThis.png","officialWebsiteLink":"https://www.npr.org/podcasts/510313/how-i-built-this","airtime":"SUN 7:30pm-8pm","meta":{"site":"news","source":"npr"},"link":"/radio/program/how-i-built-this","subscribe":{"npr":"https://rpb3r.app.goo.gl/3zxy","apple":"https://itunes.apple.com/us/podcast/how-i-built-this-with-guy-raz/id1150510297?mt=2","tuneIn":"https://tunein.com/podcasts/Arts--Culture-Podcasts/How-I-Built-This-p910896/","rss":"https://feeds.npr.org/510313/podcast.xml"}},"inside-europe":{"id":"inside-europe","title":"Inside Europe","info":"Inside Europe, a one-hour weekly news magazine hosted by Helen Seeney and Keith Walker, explores the topical issues shaping the continent. No other part of the globe has experienced such dynamic political and social change in recent years.","airtime":"SAT 3am-4am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Inside-Europe-Podcast-Tile-300x300-1.jpg","meta":{"site":"news","source":"Deutsche Welle"},"link":"/radio/program/inside-europe","subscribe":{"apple":"https://itunes.apple.com/us/podcast/inside-europe/id80106806?mt=2","tuneIn":"https://tunein.com/radio/Inside-Europe-p731/","rss":"https://partner.dw.com/xml/podcast_inside-europe"}},"latino-usa":{"id":"latino-usa","title":"Latino USA","airtime":"MON 1am-2am, SUN 6pm-7pm","info":"Latino USA, the radio journal of news and culture, is the only national, English-language radio program produced from a Latino perspective.","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/latinoUsa.jpg","officialWebsiteLink":"http://latinousa.org/","meta":{"site":"news","source":"npr"},"link":"/radio/program/latino-usa","subscribe":{"npr":"https://rpb3r.app.goo.gl/xtTd","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=79681317&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/Latino-USA-p621/","rss":"https://feeds.npr.org/510016/podcast.xml"}},"live-from-here-highlights":{"id":"live-from-here-highlights","title":"Live from Here Highlights","info":"Chris Thile steps to the mic as the host of Live from Here (formerly A Prairie Home Companion), a live public radio variety show. Download Chris’s Song of the Week plus other highlights from the broadcast. Produced by American Public Media.","airtime":"SAT 6pm-8pm, SUN 11am-1pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Live-From-Here-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.livefromhere.org/","meta":{"site":"arts","source":"american public media"},"link":"/radio/program/live-from-here-highlights","subscribe":{"apple":"https://itunes.apple.com/us/podcast/id1167173941","tuneIn":"https://tunein.com/radio/Live-from-Here-Highlights-p921744/","rss":"https://feeds.publicradio.org/public_feeds/a-prairie-home-companion-highlights/rss/rss"}},"marketplace":{"id":"marketplace","title":"Marketplace","info":"Our flagship program, helmed by Kai Ryssdal, examines what the day in money delivered, through stories, conversations, newsworthy numbers and more. Updated Monday through Friday at about 3:30 p.m. PT.","airtime":"MON-FRI 4pm-4:30pm, MON-WED 6:30pm-7pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Marketplace-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.marketplace.org/","meta":{"site":"news","source":"American Public Media"},"link":"/radio/program/marketplace","subscribe":{"apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=201853034&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/APM-Marketplace-p88/","rss":"https://feeds.publicradio.org/public_feeds/marketplace-pm/rss/rss"}},"mindshift":{"id":"mindshift","title":"MindShift","tagline":"A podcast about the future of learning and how we raise our kids","info":"The MindShift podcast explores the innovations in education that are shaping how kids learn. Hosts Ki Sung and Katrina Schwartz introduce listeners to educators, researchers, parents and students who are developing effective ways to improve how kids learn. We cover topics like how fed-up administrators are developing surprising tactics to deal with classroom disruptions; how listening to podcasts are helping kids develop reading skills; the consequences of overparenting; and why interdisciplinary learning can engage students on all ends of the traditional achievement spectrum. This podcast is part of the MindShift education site, a division of KQED News. KQED is an NPR/PBS member station based in San Francisco. You can also visit the MindShift website for episodes and supplemental blog posts or tweet us \u003ca href=\"https://twitter.com/MindShiftKQED\">@MindShiftKQED\u003c/a> or visit us at \u003ca href=\"/mindshift\">MindShift.KQED.org\u003c/a>","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Mindshift-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED MindShift: How We Will Learn","officialWebsiteLink":"/mindshift/","meta":{"site":"news","source":"kqed","order":"2"},"link":"/podcasts/mindshift","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/mindshift-podcast/id1078765985","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM1NzY0NjAwNDI5","npr":"https://www.npr.org/podcasts/464615685/mind-shift-podcast","stitcher":"https://www.stitcher.com/podcast/kqed/stories-teachers-share","spotify":"https://open.spotify.com/show/0MxSpNYZKNprFLCl7eEtyx"}},"morning-edition":{"id":"morning-edition","title":"Morning Edition","info":"\u003cem>Morning Edition\u003c/em> takes listeners around the country and the world with multi-faceted stories and commentaries every weekday. Hosts Steve Inskeep, David Greene and Rachel Martin bring you the latest breaking news and features to prepare you for the day.","airtime":"MON-FRI 3am-9am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Morning-Edition-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.npr.org/programs/morning-edition/","meta":{"site":"news","source":"npr"},"link":"/radio/program/morning-edition"},"onourwatch":{"id":"onourwatch","title":"On Our Watch","tagline":"Police secrets, unsealed","info":"For decades, the process for how police police themselves has been inconsistent – if not opaque. In some states, like California, these proceedings were completely hidden. After a new police transparency law unsealed scores of internal affairs files, our reporters set out to examine these cases and the shadow world of police discipline. On Our Watch brings listeners into the rooms where officers are questioned and witnesses are interrogated to find out who this system is really protecting. Is it the officers, or the public they've sworn to serve?","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/On-Our-Watch-Podcast-Tile-703x703-1.jpg","imageAlt":"On Our Watch from NPR and KQED","officialWebsiteLink":"/podcasts/onourwatch","meta":{"site":"news","source":"kqed","order":"1"},"link":"/podcasts/onourwatch","subscribe":{"apple":"https://podcasts.apple.com/podcast/id1567098962","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5ucHIub3JnLzUxMDM2MC9wb2RjYXN0LnhtbD9zYz1nb29nbGVwb2RjYXN0cw","npr":"https://rpb3r.app.goo.gl/onourwatch","spotify":"https://open.spotify.com/show/0OLWoyizopu6tY1XiuX70x","tuneIn":"https://tunein.com/radio/On-Our-Watch-p1436229/","stitcher":"https://www.stitcher.com/show/on-our-watch","rss":"https://feeds.npr.org/510360/podcast.xml"}},"on-the-media":{"id":"on-the-media","title":"On The Media","info":"Our weekly podcast explores how the media 'sausage' is made, casts an incisive eye on fluctuations in the marketplace of ideas, and examines threats to the freedom of information and expression in America and abroad. For one hour a week, the show tries to lift the veil from the process of \"making media,\" especially news media, because it's through that lens that we see the world and the world sees us","airtime":"SUN 2pm-3pm, MON 12am-1am","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/onTheMedia.png","officialWebsiteLink":"https://www.wnycstudios.org/shows/otm","meta":{"site":"news","source":"wnyc"},"link":"/radio/program/on-the-media","subscribe":{"apple":"https://itunes.apple.com/us/podcast/on-the-media/id73330715?mt=2","tuneIn":"https://tunein.com/radio/On-the-Media-p69/","rss":"http://feeds.wnyc.org/onthemedia"}},"our-body-politic":{"id":"our-body-politic","title":"Our Body Politic","info":"Presented by KQED, KCRW and KPCC, and created and hosted by award-winning journalist Farai Chideya, Our Body Politic is unapologetically centered on reporting on not just how women of color experience the major political events of today, but how they’re impacting those very issues.","airtime":"SAT 6pm-7pm, SUN 1am-2am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Our-Body-Politic-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://our-body-politic.simplecast.com/","meta":{"site":"news","source":"kcrw"},"link":"/radio/program/our-body-politic","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/our-body-politic/id1533069868","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5zaW1wbGVjYXN0LmNvbS9feGFQaHMxcw","spotify":"https://open.spotify.com/show/4ApAiLT1kV153TttWAmqmc","rss":"https://feeds.simplecast.com/_xaPhs1s","tuneIn":"https://tunein.com/podcasts/News--Politics-Podcasts/Our-Body-Politic-p1369211/"}},"pbs-newshour":{"id":"pbs-newshour","title":"PBS NewsHour","info":"Analysis, background reports and updates from the PBS NewsHour putting today's news in context.","airtime":"MON-FRI 3pm-4pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/PBS-News-Hour-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.pbs.org/newshour/","meta":{"site":"news","source":"pbs"},"link":"/radio/program/pbs-newshour","subscribe":{"apple":"https://itunes.apple.com/us/podcast/pbs-newshour-full-show/id394432287?mt=2","tuneIn":"https://tunein.com/radio/PBS-NewsHour---Full-Show-p425698/","rss":"https://www.pbs.org/newshour/feeds/rss/podcasts/show"}},"perspectives":{"id":"perspectives","title":"Perspectives","tagline":"KQED's series of of daily listener commentaries since 1991","info":"KQED's series of of daily listener commentaries since 1991.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Perspectives-Podcast-Tile-703x703-1.jpg","officialWebsiteLink":"/perspectives/","meta":{"site":"radio","source":"kqed","order":"15"},"link":"/perspectives","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/id73801135","npr":"https://www.npr.org/podcasts/432309616/perspectives","rss":"https://ww2.kqed.org/perspectives/category/perspectives/feed/","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93dzIua3FlZC5vcmcvcGVyc3BlY3RpdmVzL2NhdGVnb3J5L3BlcnNwZWN0aXZlcy9mZWVkLw"}},"planet-money":{"id":"planet-money","title":"Planet Money","info":"The economy explained. Imagine you could call up a friend and say, Meet me at the bar and tell me what's going on with the economy. Now imagine that's actually a fun evening.","airtime":"SUN 3pm-4pm","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/planetmoney.jpg","officialWebsiteLink":"https://www.npr.org/sections/money/","meta":{"site":"news","source":"npr"},"link":"/radio/program/planet-money","subscribe":{"npr":"https://rpb3r.app.goo.gl/M4f5","apple":"https://itunes.apple.com/us/podcast/planet-money/id290783428?mt=2","tuneIn":"https://tunein.com/podcasts/Business--Economics-Podcasts/Planet-Money-p164680/","rss":"https://feeds.npr.org/510289/podcast.xml"}},"politicalbreakdown":{"id":"politicalbreakdown","title":"Political Breakdown","tagline":"Politics from a personal perspective","info":"Political Breakdown is a new series that explores the political intersection of California and the nation. Each week hosts Scott Shafer and Marisa Lagos are joined with a new special guest to unpack politics -- with personality — and offer an insider’s glimpse at how politics happens.","airtime":"THU 6:30pm-7pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Political-Breakdown-2024-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED Political Breakdown","officialWebsiteLink":"/podcasts/politicalbreakdown","meta":{"site":"radio","source":"kqed","order":"11"},"link":"/podcasts/politicalbreakdown","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/political-breakdown/id1327641087","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM5Nzk2MzI2MTEx","npr":"https://www.npr.org/podcasts/572155894/political-breakdown","stitcher":"https://www.stitcher.com/podcast/kqed/political-breakdown","spotify":"https://open.spotify.com/show/07RVyIjIdk2WDuVehvBMoN","rss":"https://ww2.kqed.org/news/tag/political-breakdown/feed/podcast"}},"pri-the-world":{"id":"pri-the-world","title":"PRI's The World: Latest Edition","info":"Each weekday, host Marco Werman and his team of producers bring you the world's most interesting stories in an hour of radio that reminds us just how small our planet really is.","airtime":"MON-FRI 2pm-3pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/The-World-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.pri.org/programs/the-world","meta":{"site":"news","source":"PRI"},"link":"/radio/program/pri-the-world","subscribe":{"apple":"https://itunes.apple.com/us/podcast/pris-the-world-latest-edition/id278196007?mt=2","tuneIn":"https://tunein.com/podcasts/News--Politics-Podcasts/PRIs-The-World-p24/","rss":"http://feeds.feedburner.com/pri/theworld"}},"radiolab":{"id":"radiolab","title":"Radiolab","info":"A two-time Peabody Award-winner, Radiolab is an investigation told through sounds and stories, and centered around one big idea. In the Radiolab world, information sounds like music and science and culture collide. Hosted by Jad Abumrad and Robert Krulwich, the show is designed for listeners who demand skepticism, but appreciate wonder. WNYC Studios is the producer of other leading podcasts including Freakonomics Radio, Death, Sex & Money, On the Media and many more.","airtime":"SUN 12am-1am, SAT 2pm-3pm","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/radiolab1400.png","officialWebsiteLink":"https://www.wnycstudios.org/shows/radiolab/","meta":{"site":"science","source":"WNYC"},"link":"/radio/program/radiolab","subscribe":{"apple":"https://itunes.apple.com/us/podcast/radiolab/id152249110?mt=2","tuneIn":"https://tunein.com/radio/RadioLab-p68032/","rss":"https://feeds.wnyc.org/radiolab"}},"reveal":{"id":"reveal","title":"Reveal","info":"Created by The Center for Investigative Reporting and PRX, Reveal is public radios first one-hour weekly radio show and podcast dedicated to investigative reporting. Credible, fact based and without a partisan agenda, Reveal combines the power and artistry of driveway moment storytelling with data-rich reporting on critically important issues. The result is stories that inform and inspire, arming our listeners with information to right injustices, hold the powerful accountable and improve lives.Reveal is hosted by Al Letson and showcases the award-winning work of CIR and newsrooms large and small across the nation. In a radio and podcast market crowded with choices, Reveal focuses on important and often surprising stories that illuminate the world for our listeners.","airtime":"SAT 4pm-5pm","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/reveal300px.png","officialWebsiteLink":"https://www.revealnews.org/episodes/","meta":{"site":"news","source":"npr"},"link":"/radio/program/reveal","subscribe":{"apple":"https://itunes.apple.com/us/podcast/reveal/id886009669","tuneIn":"https://tunein.com/radio/Reveal-p679597/","rss":"http://feeds.revealradio.org/revealpodcast"}},"says-you":{"id":"says-you","title":"Says You!","info":"Public radio's game show of bluff and bluster, words and whimsy. The warmest, wittiest cocktail party - it's spirited and civil, brainy and boisterous, peppered with musical interludes. Fast paced and playful, it's the most fun you can have with language without getting your mouth washed out with soap. Our motto: It's not important to know the answers, it's important to like the answers!","airtime":"SUN 4pm-5pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Says-You-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"http://www.saysyouradio.com/","meta":{"site":"comedy","source":"Pipit and Finch"},"link":"/radio/program/says-you","subscribe":{"apple":"https://itunes.apple.com/us/podcast/says-you!/id1050199826","tuneIn":"https://tunein.com/radio/Says-You-p480/","rss":"https://saysyou.libsyn.com/rss"}},"science-friday":{"id":"science-friday","title":"Science Friday","info":"Science Friday is a weekly science talk show, broadcast live over public radio stations nationwide. Each week, the show focuses on science topics that are in the news and tries to bring an educated, balanced discussion to bear on the scientific issues at hand. Panels of expert guests join host Ira Flatow, a veteran science journalist, to discuss science and to take questions from listeners during the call-in portion of the program.","airtime":"FRI 11am-1pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Science-Friday-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.wnycstudios.org/shows/science-friday","meta":{"site":"news","source":"npr"},"link":"/radio/program/science-friday","subscribe":{"apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=73329284&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/Science-Friday-p394/","rss":"http://feeds.wnyc.org/science-friday"}},"science-podcast":{"id":"science-podcast","title":"KQED Science News","tagline":"From the lab, to your ears","info":"KQED Science explores science and environment news, trends, and events from the Bay Area and beyond.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Science-News-Podcast-Tile-703x703-1.jpg","officialWebsiteLink":"https://ww2.kqed.org/science/category/science-podcast/","meta":{"site":"science","source":"kqed","order":"17"},"link":"/science/category/science-podcast","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/kqed-science-news/id214663465","google":"https://podcasts.google.com/feed/aHR0cDovL2Jsb2dzLmtxZWQub3JnL3NjaWVuY2UvZmVlZC8","stitcher":"https://www.stitcher.com/podcast/kqed-science-news","rss":"https://ww2.kqed.org/science/category/science-podcast/feed/podcast"}},"selected-shorts":{"id":"selected-shorts","title":"Selected Shorts","info":"Spellbinding short stories by established and emerging writers take on a new life when they are performed by stars of the stage and screen.","airtime":"SAT 8pm-9pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Selected-Shorts-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.pri.org/programs/selected-shorts","meta":{"site":"arts","source":"pri"},"link":"/radio/program/selected-shorts","subscribe":{"apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=253191824&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/Selected-Shorts-p31792/","rss":"https://feeds.megaphone.fm/selectedshorts"}},"snap-judgment":{"id":"snap-judgment","title":"Snap Judgment","info":"Snap Judgment (Storytelling, with a BEAT) mixes real stories with killer beats to produce cinematic, dramatic, kick-ass radio. Snap’s raw, musical brand of storytelling dares listeners to see the world through the eyes of another. WNYC studios is the producer of leading podcasts including Radiolab, Freakonomics Radio, Note To Self, Here’s The Thing With Alec Baldwin, and more.","airtime":"SAT 1pm-2pm, 9pm-10pm","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/snapJudgement.jpg","officialWebsiteLink":"https://snapjudgment.org","meta":{"site":"arts","source":"WNYC"},"link":"/radio/program/snap-judgment","subscribe":{"apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=283657561&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/Snap-Judgment-p243817/","rss":"https://feeds.feedburner.com/snapjudgment-wnyc"}},"soldout":{"id":"soldout","title":"SOLD OUT: Rethinking Housing in America","tagline":"A new future for housing","info":"Sold Out: Rethinking Housing in America","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Sold-Out-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED Sold Out: Rethinking Housing in America","officialWebsiteLink":"/podcasts/soldout","meta":{"site":"news","source":"kqed","order":3},"link":"/podcasts/soldout","subscribe":{"npr":"https://www.npr.org/podcasts/911586047/s-o-l-d-o-u-t-a-new-future-for-housing","apple":"https://podcasts.apple.com/us/podcast/introducing-sold-out-rethinking-housing-in-america/id1531354937","rss":"https://feeds.megaphone.fm/soldout","spotify":"https://open.spotify.com/show/38dTBSk2ISFoPiyYNoKn1X","stitcher":"https://www.stitcher.com/podcast/kqed/sold-out-rethinking-housing-in-america","tunein":"https://tunein.com/radio/SOLD-OUT-Rethinking-Housing-in-America-p1365871/","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vc29sZG91dA"}},"ted-radio-hour":{"id":"ted-radio-hour","title":"TED Radio Hour","info":"The TED Radio Hour is a journey through fascinating ideas, astonishing inventions, fresh approaches to old problems, and new ways to think and create.","airtime":"SUN 3pm-4pm, SAT 10pm-11pm","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/tedRadioHour.jpg","officialWebsiteLink":"https://www.npr.org/programs/ted-radio-hour/?showDate=2018-06-22","meta":{"site":"news","source":"npr"},"link":"/radio/program/ted-radio-hour","subscribe":{"npr":"https://rpb3r.app.goo.gl/8vsS","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=523121474&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/TED-Radio-Hour-p418021/","rss":"https://feeds.npr.org/510298/podcast.xml"}},"tech-nation":{"id":"tech-nation","title":"Tech Nation Radio Podcast","info":"Tech Nation is a weekly public radio program, hosted by Dr. Moira Gunn. Founded in 1993, it has grown from a simple interview show to a multi-faceted production, featuring conversations with noted technology and science leaders, and a weekly science and technology-related commentary.","airtime":"FRI 10pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Tech-Nation-Radio-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"http://technation.podomatic.com/","meta":{"site":"science","source":"Tech Nation Media"},"link":"/radio/program/tech-nation","subscribe":{"rss":"https://technation.podomatic.com/rss2.xml"}},"thebay":{"id":"thebay","title":"The Bay","tagline":"Local news to keep you rooted","info":"Host Devin Katayama walks you through the biggest story of the day with reporters and newsmakers.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/The-Bay-Podcast-Tile-703x703-1.jpg","imageAlt":"\"KQED The Bay","officialWebsiteLink":"/podcasts/thebay","meta":{"site":"radio","source":"kqed","order":"6"},"link":"/podcasts/thebay","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/the-bay/id1350043452","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM4MjU5Nzg2MzI3","npr":"https://www.npr.org/podcasts/586725995/the-bay","stitcher":"https://www.stitcher.com/podcast/kqed/the-bay","spotify":"https://open.spotify.com/show/4BIKBKIujizLHlIlBNaAqQ","rss":"https://feeds.megaphone.fm/KQINC8259786327"}},"californiareport":{"id":"californiareport","title":"The California Report","tagline":"California, day by day","info":"KQED’s statewide radio news program providing daily coverage of issues, trends and public policy decisions.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/The-California-Report-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED The California Report","officialWebsiteLink":"/californiareport","meta":{"site":"news","source":"kqed","order":"9"},"link":"/californiareport","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/kqeds-the-california-report/id79681292","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM1MDAyODE4NTgz","npr":"https://www.npr.org/podcasts/432285393/the-california-report","stitcher":"https://www.stitcher.com/podcast/kqedfm-kqeds-the-california-report-podcast-8838","rss":"https://ww2.kqed.org/news/tag/tcram/feed/podcast"}},"californiareportmagazine":{"id":"californiareportmagazine","title":"The California Report Magazine","tagline":"Your state, your stories","info":"Every week, The California Report Magazine takes you on a road trip for the ears: to visit the places and meet the people who make California unique. The in-depth storytelling podcast from the California Report.","airtime":"FRI 4:30pm-5pm, 6:30pm-7pm, 11pm-11:30pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/The-California-Report-Magazine-Podcast-Tile-703x703-1.jpg","officialWebsiteLink":"/californiareportmagazine","meta":{"site":"news","source":"kqed","order":"10"},"link":"/californiareportmagazine","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/the-california-report-magazine/id1314750545","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM3NjkwNjk1OTAz","npr":"https://www.npr.org/podcasts/564733126/the-california-report-magazine","stitcher":"https://www.stitcher.com/podcast/kqed/the-california-report-magazine","rss":"https://ww2.kqed.org/news/tag/tcrmag/feed/podcast"}},"theleap":{"id":"theleap","title":"The Leap","tagline":"What if you closed your eyes, and jumped?","info":"Stories about people making dramatic, risky changes, told by award-winning public radio reporter Judy Campbell.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/The-Leap-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED The Leap","officialWebsiteLink":"/podcasts/theleap","meta":{"site":"news","source":"kqed","order":"14"},"link":"/podcasts/theleap","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/the-leap/id1046668171","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkM0NTcwODQ2MjY2","npr":"https://www.npr.org/podcasts/447248267/the-leap","stitcher":"https://www.stitcher.com/podcast/kqed/the-leap","spotify":"https://open.spotify.com/show/3sSlVHHzU0ytLwuGs1SD1U","rss":"https://ww2.kqed.org/news/programs/the-leap/feed/podcast"}},"masters-of-scale":{"id":"masters-of-scale","title":"Masters of Scale","info":"Masters of Scale is an original podcast in which LinkedIn co-founder and Greylock Partner Reid Hoffman sets out to describe and prove theories that explain how great entrepreneurs take their companies from zero to a gazillion in ingenious fashion.","airtime":"Every other Wednesday June 12 through October 16 at 8pm (repeats Thursdays at 2am)","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Masters-of-Scale-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://mastersofscale.com/","meta":{"site":"radio","source":"WaitWhat"},"link":"/radio/program/masters-of-scale","subscribe":{"apple":"http://mastersofscale.app.link/","rss":"https://rss.art19.com/masters-of-scale"}},"the-moth-radio-hour":{"id":"the-moth-radio-hour","title":"The Moth Radio Hour","info":"Since its launch in 1997, The Moth has presented thousands of true stories, told live and without notes, to standing-room-only crowds worldwide. Moth storytellers stand alone, under a spotlight, with only a microphone and a roomful of strangers. The storyteller and the audience embark on a high-wire act of shared experience which is both terrifying and exhilarating. Since 2008, The Moth podcast has featured many of our favorite stories told live on Moth stages around the country. For information on all of our programs and live events, visit themoth.org.","airtime":"SAT 8pm-9pm and SUN 11am-12pm","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/theMoth.jpg","officialWebsiteLink":"https://themoth.org/","meta":{"site":"arts","source":"prx"},"link":"/radio/program/the-moth-radio-hour","subscribe":{"apple":"https://itunes.apple.com/us/podcast/the-moth-podcast/id275699983?mt=2","tuneIn":"https://tunein.com/radio/The-Moth-p273888/","rss":"http://feeds.themoth.org/themothpodcast"}},"the-new-yorker-radio-hour":{"id":"the-new-yorker-radio-hour","title":"The New Yorker Radio Hour","info":"The New Yorker Radio Hour is a weekly program presented by the magazine's editor, David Remnick, and produced by WNYC Studios and The New Yorker. Each episode features a diverse mix of interviews, profiles, storytelling, and an occasional burst of humor inspired by the magazine, and shaped by its writers, artists, and editors. This isn't a radio version of a magazine, but something all its own, reflecting the rich possibilities of audio storytelling and conversation. Theme music for the show was composed and performed by Merrill Garbus of tUnE-YArDs.","airtime":"SAT 10am-11am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/The-New-Yorker-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.wnycstudios.org/shows/tnyradiohour","meta":{"site":"arts","source":"WNYC"},"link":"/radio/program/the-new-yorker-radio-hour","subscribe":{"apple":"https://itunes.apple.com/us/podcast/id1050430296","tuneIn":"https://tunein.com/podcasts/WNYC-Podcasts/New-Yorker-Radio-Hour-p803804/","rss":"https://feeds.feedburner.com/newyorkerradiohour"}},"the-takeaway":{"id":"the-takeaway","title":"The Takeaway","info":"The Takeaway is produced in partnership with its national audience. It delivers perspective and analysis to help us better understand the day’s news. Be a part of the American conversation on-air and online.","airtime":"MON-THU 12pm-1pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/The-Takeaway-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.wnycstudios.org/shows/takeaway","meta":{"site":"news","source":"WNYC"},"link":"/radio/program/the-takeaway","subscribe":{"apple":"https://itunes.apple.com/us/podcast/the-takeaway/id363143310?mt=2","tuneIn":"http://tunein.com/radio/The-Takeaway-p150731/","rss":"https://feeds.feedburner.com/takeawaypodcast"}},"this-american-life":{"id":"this-american-life","title":"This American Life","info":"This American Life is a weekly public radio show, heard by 2.2 million people on more than 500 stations. Another 2.5 million people download the weekly podcast. It is hosted by Ira Glass, produced in collaboration with Chicago Public Media, delivered to stations by PRX The Public Radio Exchange, and has won all of the major broadcasting awards.","airtime":"SAT 12pm-1pm, 7pm-8pm","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/thisAmericanLife.png","officialWebsiteLink":"https://www.thisamericanlife.org/","meta":{"site":"news","source":"wbez"},"link":"/radio/program/this-american-life","subscribe":{"apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=201671138&at=11l79Y&ct=nprdirectory","rss":"https://www.thisamericanlife.org/podcast/rss.xml"}},"truthbetold":{"id":"truthbetold","title":"Truth Be Told","tagline":"Advice by and for people of color","info":"We’re the friend you call after a long day, the one who gets it. Through wisdom from some of the greatest thinkers of our time, host Tonya Mosley explores what it means to grow and thrive as a Black person in America, while discovering new ways of being that serve as a portal to more love, more healing, and more joy.","airtime":"","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Truth-Be-Told-Podcast-Tile-360x360-1.jpg","imageAlt":"KQED Truth Be Told with Tonya Mosley","officialWebsiteLink":"https://www.kqed.ord/podcasts/truthbetold","meta":{"site":"news","source":"npr","order":"12"},"link":"/podcasts/truthbetold","subscribe":{"apple":"https://podcasts.apple.com/us/podcast/truth-be-told/id1462216572","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93dzIua3FlZC5vcmcvbmV3cy9jYXRlZ29yeS90cnV0aC1iZS10b2xkLXBvZGNhc3QvZmVlZA","npr":"https://www.npr.org/podcasts/719210818/truth-be-told","stitcher":"https://www.stitcher.com/s?fid=398170&refid=stpr","spotify":"https://open.spotify.com/show/587DhwTBxke6uvfwDfaV5N"}},"wait-wait-dont-tell-me":{"id":"wait-wait-dont-tell-me","title":"Wait Wait... Don't Tell Me!","info":"Peter Sagal and Bill Kurtis host the weekly NPR News quiz show alongside some of the best and brightest news and entertainment personalities.","airtime":"SUN 10am-11am, SAT 11am-12pm, SAT 6pm-7pm","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Wait-Wait-Podcast-Tile-300x300-1.jpg","officialWebsiteLink":"https://www.npr.org/programs/wait-wait-dont-tell-me/","meta":{"site":"news","source":"npr"},"link":"/radio/program/wait-wait-dont-tell-me","subscribe":{"npr":"https://rpb3r.app.goo.gl/Xogv","apple":"https://itunes.apple.com/WebObjects/MZStore.woa/wa/viewPodcast?s=143441&mt=2&id=121493804&at=11l79Y&ct=nprdirectory","tuneIn":"https://tunein.com/radio/Wait-Wait-Dont-Tell-Me-p46/","rss":"https://feeds.npr.org/344098539/podcast.xml"}},"washington-week":{"id":"washington-week","title":"Washington Week","info":"For 50 years, Washington Week has been the most intelligent and up to date conversation about the most important news stories of the week. Washington Week is the longest-running news and public affairs program on PBS and features journalists -- not pundits -- lending insight and perspective to the week's important news stories.","airtime":"SAT 1:30am-2am","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/04/washington-week.jpg","officialWebsiteLink":"http://www.pbs.org/weta/washingtonweek/","meta":{"site":"news","source":"pbs"},"link":"/radio/program/washington-week","subscribe":{"apple":"https://itunes.apple.com/us/podcast/washington-week-audio-pbs/id83324702?mt=2","tuneIn":"https://tunein.com/podcasts/Current-Affairs/Washington-Week-p693/","rss":"http://feeds.pbs.org/pbs/weta/washingtonweek-audio"}},"weekend-edition-saturday":{"id":"weekend-edition-saturday","title":"Weekend Edition Saturday","info":"Weekend Edition Saturday wraps up the week's news and offers a mix of analysis and features on a wide range of topics, including arts, sports, entertainment, and human interest stories. The two-hour program is hosted by NPR's Peabody Award-winning Scott Simon.","airtime":"SAT 5am-10am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Weekend-Edition-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.npr.org/programs/weekend-edition-saturday/","meta":{"site":"news","source":"npr"},"link":"/radio/program/weekend-edition-saturday"},"weekend-edition-sunday":{"id":"weekend-edition-sunday","title":"Weekend Edition Sunday","info":"Weekend Edition Sunday features interviews with newsmakers, artists, scientists, politicians, musicians, writers, theologians and historians. The program has covered news events from Nelson Mandela's 1990 release from a South African prison to the capture of Saddam Hussein.","airtime":"SUN 5am-10am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Weekend-Edition-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.npr.org/programs/weekend-edition-sunday/","meta":{"site":"news","source":"npr"},"link":"/radio/program/weekend-edition-sunday"},"world-affairs":{"id":"world-affairs","title":"World Affairs","info":"The world as we knew it is undergoing a rapid transformation…so what's next? Welcome to WorldAffairs, your guide to a changing world. We give you the context you need to navigate across borders and ideologies. Through sound-rich stories and in-depth interviews, we break down what it means to be a global citizen on a hot, crowded planet. Our hosts, Ray Suarez, Teresa Cotsirilos and Philip Yun help you make sense of an uncertain world, one story at a time.","airtime":"MON 10pm, TUE 1am, SAT 3am","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/World-Affairs-Podcast-Tile-360x360-1.jpg ","officialWebsiteLink":"https://www.worldaffairs.org/","meta":{"site":"news","source":"World Affairs"},"link":"/radio/program/world-affairs","subscribe":{"apple":"https://itunes.apple.com/us/podcast/world-affairs/id101215657?mt=2","tuneIn":"https://tunein.com/radio/WorldAffairs-p1665/","rss":"https://worldaffairs.libsyn.com/rss"}},"on-shifting-ground":{"id":"on-shifting-ground","title":"On Shifting Ground with Ray Suarez","info":"Geopolitical turmoil. A warming planet. Authoritarians on the rise. We live in a chaotic world that’s rapidly shifting around us. “On Shifting Ground with Ray Suarez” explores international fault lines and how they impact us all. Each week, NPR veteran Ray Suarez hosts conversations with journalists, leaders and policy experts to help us read between the headlines – and give us hope for human resilience.","airtime":"MON 10pm, TUE 1am, SAT 3am","imageSrc":"https://ww2.kqed.org/app/uploads/2022/12/onshiftingground-600x600-1.png","officialWebsiteLink":"https://worldaffairs.org/radio-podcast/","meta":{"site":"news","source":"On Shifting Ground"},"link":"/radio/program/on-shifting-ground","subscribe":{"apple":"https://podcasts.apple.com/ie/podcast/on-shifting-ground/id101215657","rss":"https://feeds.libsyn.com/36668/rss"}},"hidden-brain":{"id":"hidden-brain","title":"Hidden Brain","info":"Shankar Vedantam uses science and storytelling to reveal the unconscious patterns that drive human behavior, shape our choices and direct our relationships.","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/05/hiddenbrain.jpg","officialWebsiteLink":"https://www.npr.org/series/423302056/hidden-brain","airtime":"SUN 7pm-8pm","meta":{"site":"news","source":"NPR"},"link":"/radio/program/hidden-brain","subscribe":{"apple":"https://itunes.apple.com/us/podcast/hidden-brain/id1028908750?mt=2","tuneIn":"https://tunein.com/podcasts/Science-Podcasts/Hidden-Brain-p787503/","rss":"https://feeds.npr.org/510308/podcast.xml"}},"city-arts":{"id":"city-arts","title":"City Arts & Lectures","info":"A one-hour radio program to hear celebrated writers, artists and thinkers address contemporary ideas and values, often discussing the creative process. Please note: tapes or transcripts are not available","imageSrc":"https://ww2.kqed.org/radio/wp-content/uploads/sites/50/2018/05/cityartsandlecture-300x300.jpg","officialWebsiteLink":"https://www.cityarts.net/","airtime":"SUN 1pm-2pm, TUE 10pm, WED 1am","meta":{"site":"news","source":"City Arts & Lectures"},"link":"https://www.cityarts.net","subscribe":{"tuneIn":"https://tunein.com/radio/City-Arts-and-Lectures-p692/","rss":"https://www.cityarts.net/feed/"}},"white-lies":{"id":"white-lies","title":"White Lies","info":"In 1965, Rev. James Reeb was murdered in Selma, Alabama. Three men were tried and acquitted, but no one was ever held to account. Fifty years later, two journalists from Alabama return to the city where it happened, expose the lies that kept the murder from being solved and uncover a story about guilt and memory that says as much about America today as it does about the past.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/White-Lies-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.npr.org/podcasts/510343/white-lies","meta":{"site":"news","source":"npr"},"link":"/radio/program/white-lies","subscribe":{"npr":"https://rpb3r.app.goo.gl/whitelies","apple":"https://podcasts.apple.com/podcast/id1462650519?mt=2&at=11l79Y&ct=nprdirectory","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5ucHIub3JnLzUxMDM0My9wb2RjYXN0LnhtbA","spotify":"https://open.spotify.com/show/12yZ2j8vxqhc0QZyRES3ft?si=LfWYEK6URA63hueKVxRLAw","rss":"https://feeds.npr.org/510343/podcast.xml"}},"rightnowish":{"id":"rightnowish","title":"Rightnowish","tagline":"Art is where you find it","info":"Rightnowish digs into life in the Bay Area right now… ish. Journalist Pendarvis Harshaw takes us to galleries painted on the sides of liquor stores in West Oakland. We'll dance in warehouses in the Bayview, make smoothies with kids in South Berkeley, and listen to classical music in a 1984 Cutlass Supreme in Richmond. Every week, Pen talks to movers and shakers about how the Bay Area shapes what they create, and how they shape the place we call home.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/Rightnowish-Podcast-Tile-500x500-1.jpg","imageAlt":"KQED Rightnowish with Pendarvis Harshaw","officialWebsiteLink":"/podcasts/rightnowish","meta":{"site":"arts","source":"kqed","order":"5"},"link":"/podcasts/rightnowish","subscribe":{"npr":"https://www.npr.org/podcasts/721590300/rightnowish","rss":"https://ww2.kqed.org/arts/programs/rightnowish/feed/podcast","apple":"https://podcasts.apple.com/us/podcast/rightnowish/id1482187648","stitcher":"https://www.stitcher.com/podcast/kqed/rightnowish","google":"https://podcasts.google.com/feed/aHR0cHM6Ly9mZWVkcy5tZWdhcGhvbmUuZm0vS1FJTkMxMjU5MTY3NDc4","spotify":"https://open.spotify.com/show/7kEJuafTzTVan7B78ttz1I"}},"jerrybrown":{"id":"jerrybrown","title":"The Political Mind of Jerry Brown","tagline":"Lessons from a lifetime in politics","info":"The Political Mind of Jerry Brown brings listeners the wisdom of the former Governor, Mayor, and presidential candidate. Scott Shafer interviewed Brown for more than 40 hours, covering the former governor's life and half-century in the political game and Brown has some lessons he'd like to share. ","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/The-Political-Mind-of-Jerry-Brown-Podcast-Tile-703x703-1.jpg","imageAlt":"KQED The Political Mind of Jerry Brown","officialWebsiteLink":"/podcasts/jerrybrown","meta":{"site":"news","source":"kqed","order":"16"},"link":"/podcasts/jerrybrown","subscribe":{"npr":"https://www.npr.org/podcasts/790253322/the-political-mind-of-jerry-brown","apple":"https://itunes.apple.com/us/podcast/id1492194549","rss":"https://ww2.kqed.org/news/series/jerrybrown/feed/podcast/","tuneIn":"http://tun.in/pjGcK","stitcher":"https://www.stitcher.com/podcast/kqed/the-political-mind-of-jerry-brown","spotify":"https://open.spotify.com/show/54C1dmuyFyKMFttY6X2j6r?si=K8SgRCoISNK6ZbjpXrX5-w","google":"https://podcasts.google.com/feed/aHR0cHM6Ly93dzIua3FlZC5vcmcvbmV3cy9zZXJpZXMvamVycnlicm93bi9mZWVkL3BvZGNhc3Qv"}},"the-splendid-table":{"id":"the-splendid-table","title":"The Splendid Table","info":"\u003cem>The Splendid Table\u003c/em> hosts our nation's conversations about cooking, sustainability and food culture.","imageSrc":"https://cdn.kqed.org/wp-content/uploads/2024/04/The-Splendid-Table-Podcast-Tile-360x360-1.jpg","officialWebsiteLink":"https://www.splendidtable.org/","airtime":"SUN 10-11 pm","meta":{"site":"radio","source":"npr"},"link":"/radio/program/the-splendid-table"}},"racesReducer":{"5921":{"id":"5921","type":"apRace","location":"State of California","raceName":"U.S. House of Representatives, District 7","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":158422,"precinctsReportPercentage":98.97,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:48 PM","source":"AP","candidates":[{"candidateName":"Doris Matsui","candidateIncumbent":true,"candidateParty":"D","voteCount":89456,"isWinner":true},{"candidateName":"Tom Silva","candidateIncumbent":false,"candidateParty":"R","voteCount":48920,"isWinner":true},{"candidateName":"David Mandel","candidateIncumbent":false,"candidateParty":"D","voteCount":20046,"isWinner":false}],"winnerDateTime":"2024-03-09T01:00:38.194Z"},"5922":{"id":"5922","type":"apRace","location":"State of California","raceName":"U.S. House of Representatives, District 8","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":0,"uncontested":true,"precinctsReportPercentage":0,"eevp":0,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Rudy Recile","candidateIncumbent":false,"candidateParty":"R","voteCount":0,"isWinner":true},{"candidateName":"John Garamendi","candidateIncumbent":true,"candidateParty":"D","voteCount":0,"isWinner":true}],"winnerDateTime":"2024-03-06T04:00:30.000Z"},"5924":{"id":"5924","type":"apRace","location":"State of California","raceName":"U.S. House of Representatives, District 10","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":185034,"precinctsReportPercentage":99.07,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:48 PM","source":"AP","candidates":[{"candidateName":"Mark DeSaulnier","candidateIncumbent":true,"candidateParty":"D","voteCount":121265,"isWinner":true},{"candidateName":"Katherine Piccinini","candidateIncumbent":false,"candidateParty":"R","voteCount":34883,"isWinner":true},{"candidateName":"Nolan Chen","candidateIncumbent":false,"candidateParty":"R","voteCount":19459,"isWinner":false},{"candidateName":"Joe Sweeney","candidateIncumbent":false,"candidateParty":"NPP","voteCount":7606,"isWinner":false},{"candidateName":"Mohamed Elsherbini","candidateIncumbent":false,"candidateParty":"NPP","voteCount":1821,"isWinner":false}],"winnerDateTime":"2024-03-09T01:02:32.415Z"},"5926":{"id":"5926","type":"apRace","location":"State of California","raceName":"U.S. House of Representatives, District 12","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":153801,"precinctsReportPercentage":98.88,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 20, 2024","timeUpdated":"4:41 PM","source":"AP","candidates":[{"candidateName":"Lateefah Simon","candidateIncumbent":false,"candidateParty":"D","voteCount":85905,"isWinner":true},{"candidateName":"Jennifer Tran","candidateIncumbent":false,"candidateParty":"D","voteCount":22964,"isWinner":true},{"candidateName":"Tony Daysog","candidateIncumbent":false,"candidateParty":"D","voteCount":17197,"isWinner":false},{"candidateName":"Stephen Slauson","candidateIncumbent":false,"candidateParty":"R","voteCount":9699,"isWinner":false},{"candidateName":"Glenn Kaplan","candidateIncumbent":false,"candidateParty":"D","voteCount":6785,"isWinner":false},{"candidateName":"Eric Wilson","candidateIncumbent":false,"candidateParty":"D","voteCount":4243,"isWinner":false},{"candidateName":"Abdur Sikder","candidateIncumbent":false,"candidateParty":"D","voteCount":2847,"isWinner":false},{"candidateName":"Ned Nuerge","candidateIncumbent":false,"candidateParty":"R","voteCount":2532,"isWinner":false},{"candidateName":"Andre Todd","candidateIncumbent":false,"candidateParty":"D","voteCount":1629,"isWinner":false}],"winnerDateTime":"2024-03-16T00:22:36.062Z"},"5928":{"id":"5928","type":"apRace","location":"State of California","raceName":"U.S. House of Representatives, District 14","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":125831,"precinctsReportPercentage":99.14,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 20, 2024","timeUpdated":"4:41 PM","source":"AP","candidates":[{"candidateName":"Eric Swalwell","candidateIncumbent":true,"candidateParty":"D","voteCount":83989,"isWinner":true},{"candidateName":"Vin Kruttiventi","candidateIncumbent":false,"candidateParty":"R","voteCount":22106,"isWinner":true},{"candidateName":"Alison Hayden","candidateIncumbent":false,"candidateParty":"R","voteCount":11928,"isWinner":false},{"candidateName":"Luis Reynoso","candidateIncumbent":false,"candidateParty":"R","voteCount":7808,"isWinner":false}],"winnerDateTime":"2024-03-12T00:51:36.366Z"},"5930":{"id":"5930","type":"apRace","location":"State of California","raceName":"U.S. House of Representatives, District 16","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":182135,"precinctsReportPercentage":98.91,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"April 3, 2024","timeUpdated":"3:04 PM","source":"AP","candidates":[{"candidateName":"Sam Liccardo","candidateIncumbent":false,"candidateParty":"D","voteCount":38489,"isWinner":true},{"candidateName":"Evan Low","candidateIncumbent":false,"candidateParty":"D","voteCount":30249,"isWinner":false},{"candidateName":"Joe Simitian","candidateIncumbent":false,"candidateParty":"D","voteCount":30249,"isWinner":false},{"candidateName":"Peter Ohtaki","candidateIncumbent":false,"candidateParty":"R","voteCount":23275,"isWinner":false},{"candidateName":"Peter Dixon","candidateIncumbent":false,"candidateParty":"D","voteCount":14673,"isWinner":false},{"candidateName":"Rishi Kumar","candidateIncumbent":false,"candidateParty":"D","voteCount":12377,"isWinner":false},{"candidateName":"Karl Ryan","candidateIncumbent":false,"candidateParty":"R","voteCount":11557,"isWinner":false},{"candidateName":"Julie Lythcott-Haims","candidateIncumbent":false,"candidateParty":"D","voteCount":11383,"isWinner":false},{"candidateName":"Ahmed Mostafa","candidateIncumbent":false,"candidateParty":"D","voteCount":5811,"isWinner":false},{"candidateName":"Greg Tanaka","candidateIncumbent":false,"candidateParty":"D","voteCount":2421,"isWinner":false},{"candidateName":"Joby Bernstein","candidateIncumbent":false,"candidateParty":"D","voteCount":1651,"isWinner":false}],"winnerDateTime":"2024-03-12T00:32:05.002Z"},"5931":{"id":"5931","type":"apRace","location":"State of California","raceName":"U.S. House of Representatives, District 17","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":117534,"precinctsReportPercentage":98.92,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Ro Khanna","candidateIncumbent":true,"candidateParty":"D","voteCount":73941,"isWinner":true},{"candidateName":"Anita Chen","candidateIncumbent":false,"candidateParty":"R","voteCount":31539,"isWinner":true},{"candidateName":"Ritesh Tandon","candidateIncumbent":false,"candidateParty":"D","voteCount":5728,"isWinner":false},{"candidateName":"Mario Ramirez","candidateIncumbent":false,"candidateParty":"D","voteCount":4491,"isWinner":false},{"candidateName":"Joe Dehn","candidateIncumbent":false,"candidateParty":"Lib","voteCount":1835,"isWinner":false}],"winnerDateTime":"2024-03-08T01:50:53.956Z"},"5932":{"id":"5932","type":"apRace","location":"State of California","raceName":"U.S. House of Representatives, District 18","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":96302,"precinctsReportPercentage":98.93,"eevp":98.83,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 25, 2024","timeUpdated":"5:47 AM","source":"AP","candidates":[{"candidateName":"Zoe Lofgren","candidateIncumbent":true,"candidateParty":"D","voteCount":49323,"isWinner":true},{"candidateName":"Peter Hernandez","candidateIncumbent":false,"candidateParty":"R","voteCount":31622,"isWinner":true},{"candidateName":"Charlene Nijmeh","candidateIncumbent":false,"candidateParty":"D","voteCount":10614,"isWinner":false},{"candidateName":"Lawrence Milan","candidateIncumbent":false,"candidateParty":"D","voteCount":2712,"isWinner":false},{"candidateName":"Luele Kifle","candidateIncumbent":false,"candidateParty":"D","voteCount":2031,"isWinner":false}],"winnerDateTime":"2024-03-12T00:26:02.706Z"},"5963":{"id":"5963","type":"apRace","location":"State of California","raceName":"State House, District 2","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":139085,"precinctsReportPercentage":98.62,"eevp":98.6,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Michael Greer","candidateIncumbent":false,"candidateParty":"R","voteCount":38079,"isWinner":true},{"candidateName":"Chris Rogers","candidateIncumbent":false,"candidateParty":"D","voteCount":27126,"isWinner":true},{"candidateName":"Rusty Hicks","candidateIncumbent":false,"candidateParty":"D","voteCount":25615,"isWinner":false},{"candidateName":"Ariel Kelley","candidateIncumbent":false,"candidateParty":"D","voteCount":19483,"isWinner":false},{"candidateName":"Frankie Myers","candidateIncumbent":false,"candidateParty":"D","voteCount":17694,"isWinner":false},{"candidateName":"Ted Williams","candidateIncumbent":false,"candidateParty":"D","voteCount":9550,"isWinner":false},{"candidateName":"Cynthia Click","candidateIncumbent":false,"candidateParty":"D","voteCount":1538,"isWinner":false}],"winnerDateTime":"2024-03-22T21:38:36.711Z"},"5972":{"id":"5972","type":"apRace","location":"State of California","raceName":"State House, District 11","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":99775,"precinctsReportPercentage":99,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:48 PM","source":"AP","candidates":[{"candidateName":"Lori Wilson","candidateIncumbent":true,"candidateParty":"D","voteCount":50085,"isWinner":true},{"candidateName":"Dave Ennis","candidateIncumbent":false,"candidateParty":"R","voteCount":26074,"isWinner":true},{"candidateName":"Wanda Wallis","candidateIncumbent":false,"candidateParty":"R","voteCount":14638,"isWinner":false},{"candidateName":"Jeffrey Flack","candidateIncumbent":false,"candidateParty":"D","voteCount":8978,"isWinner":false}],"winnerDateTime":"2024-03-08T02:01:24.524Z"},"5973":{"id":"5973","type":"apRace","location":"State of California","raceName":"State House, District 12","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":143532,"precinctsReportPercentage":99.19,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:38 PM","source":"AP","candidates":[{"candidateName":"Damon Connolly","candidateIncumbent":true,"candidateParty":"D","voteCount":111275,"isWinner":true},{"candidateName":"Andy Podshadley","candidateIncumbent":false,"candidateParty":"R","voteCount":17240,"isWinner":true},{"candidateName":"Eryn Cervantes","candidateIncumbent":false,"candidateParty":"R","voteCount":15017,"isWinner":false}],"winnerDateTime":"2024-03-21T00:25:32.262Z"},"5975":{"id":"5975","type":"apRace","location":"State of California","raceName":"State House, District 14","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":106997,"precinctsReportPercentage":99.06,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:48 PM","source":"AP","candidates":[{"candidateName":"Buffy Wicks","candidateIncumbent":true,"candidateParty":"D","voteCount":78678,"isWinner":true},{"candidateName":"Margot Smith","candidateIncumbent":false,"candidateParty":"D","voteCount":18251,"isWinner":true},{"candidateName":"Utkarsh Jain","candidateIncumbent":false,"candidateParty":"R","voteCount":10068,"isWinner":false}],"winnerDateTime":"2024-03-15T01:30:34.539Z"},"5976":{"id":"5976","type":"apRace","location":"State of California","raceName":"State House, District 15","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":97144,"precinctsReportPercentage":98.98,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:48 PM","source":"AP","candidates":[{"candidateName":"Sonia Ledo","candidateIncumbent":false,"candidateParty":"R","voteCount":30946,"isWinner":true},{"candidateName":"Anamarie Farias","candidateIncumbent":false,"candidateParty":"D","voteCount":29512,"isWinner":true},{"candidateName":"Monica Wilson","candidateIncumbent":false,"candidateParty":"D","voteCount":24775,"isWinner":false},{"candidateName":"Karen Mitchoff","candidateIncumbent":false,"candidateParty":"D","voteCount":11911,"isWinner":false}],"winnerDateTime":"2024-03-14T00:19:38.858Z"},"5977":{"id":"5977","type":"apRace","location":"State of California","raceName":"State House, District 16","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":0,"uncontested":true,"precinctsReportPercentage":0,"eevp":0,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Joseph Rubay","candidateIncumbent":false,"candidateParty":"R","voteCount":0,"isWinner":true},{"candidateName":"Rebecca Bauer-Kahan","candidateIncumbent":true,"candidateParty":"D","voteCount":0,"isWinner":true}],"winnerDateTime":"2024-03-06T04:00:30.000Z"},"5978":{"id":"5978","type":"apRace","location":"State of California","raceName":"State House, District 17","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":111003,"precinctsReportPercentage":98.99,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"8:25 AM","source":"AP","candidates":[{"candidateName":"Matt Haney","candidateIncumbent":true,"candidateParty":"D","voteCount":90915,"isWinner":true},{"candidateName":"Manuel Noris-Barrera","candidateIncumbent":false,"candidateParty":"R","voteCount":13843,"isWinner":true},{"candidateName":"Otto Duke","candidateIncumbent":false,"candidateParty":"D","voteCount":6245,"isWinner":false}],"winnerDateTime":"2024-03-12T00:36:19.697Z"},"5979":{"id":"5979","type":"apRace","location":"State of California","raceName":"State House, District 18","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":86008,"precinctsReportPercentage":99.1,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 20, 2024","timeUpdated":"4:41 PM","source":"AP","candidates":[{"candidateName":"Mia Bonta","candidateIncumbent":true,"candidateParty":"D","voteCount":73040,"isWinner":true},{"candidateName":"Andre Sandford","candidateIncumbent":false,"candidateParty":"AIP","voteCount":4575,"isWinner":false},{"candidateName":"Mindy Pechenuk","candidateIncumbent":false,"candidateParty":"R","voteCount":4389,"isWinner":false},{"candidateName":"Cheyenne Kenney","candidateIncumbent":false,"candidateParty":"R","voteCount":4004,"isWinner":false}],"winnerDateTime":"2024-03-06T08:03:23.729Z"},"5980":{"id":"5980","type":"apRace","location":"State of California","raceName":"State House, District 19","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":113959,"precinctsReportPercentage":98.8,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Catherine Stefani","candidateIncumbent":false,"candidateParty":"D","voteCount":64960,"isWinner":true},{"candidateName":"David Lee","candidateIncumbent":false,"candidateParty":"D","voteCount":33035,"isWinner":true},{"candidateName":"Nadia Flamenco","candidateIncumbent":false,"candidateParty":"R","voteCount":8335,"isWinner":false},{"candidateName":"Arjun Sodhani","candidateIncumbent":false,"candidateParty":"R","voteCount":7629,"isWinner":false}],"winnerDateTime":"2024-03-11T23:50:23.109Z"},"5981":{"id":"5981","type":"apRace","location":"State of California","raceName":"State House, District 20","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":0,"uncontested":true,"precinctsReportPercentage":0,"eevp":0,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 20, 2024","timeUpdated":"4:36 PM","source":"AP","candidates":[{"candidateName":"Liz Ortega","candidateIncumbent":true,"candidateParty":"D","voteCount":0,"isWinner":true}],"winnerDateTime":"2024-03-06T04:00:30.000Z"},"5982":{"id":"5982","type":"apRace","location":"State of California","raceName":"State House, District 21","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":0,"uncontested":true,"precinctsReportPercentage":0,"eevp":0,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Mark Gilham","candidateIncumbent":false,"candidateParty":"R","voteCount":0,"isWinner":true},{"candidateName":"Diane Papan","candidateIncumbent":true,"candidateParty":"D","voteCount":0,"isWinner":true}],"winnerDateTime":"2024-03-06T04:00:30.000Z"},"5984":{"id":"5984","type":"apRace","location":"State of California","raceName":"State House, District 23","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":116963,"precinctsReportPercentage":98.91,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Marc Berman","candidateIncumbent":true,"candidateParty":"D","voteCount":67106,"isWinner":true},{"candidateName":"Lydia Kou","candidateIncumbent":false,"candidateParty":"D","voteCount":23699,"isWinner":true},{"candidateName":"Gus Mattammal","candidateIncumbent":false,"candidateParty":"R","voteCount":13277,"isWinner":false},{"candidateName":"Allan Marson","candidateIncumbent":false,"candidateParty":"R","voteCount":12881,"isWinner":false}],"winnerDateTime":"2024-03-12T01:13:06.280Z"},"5987":{"id":"5987","type":"apRace","location":"State of California","raceName":"State House, District 26","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":72753,"precinctsReportPercentage":99.19,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Patrick Ahrens","candidateIncumbent":false,"candidateParty":"D","voteCount":25036,"isWinner":true},{"candidateName":"Tara Sreekrishnan","candidateIncumbent":false,"candidateParty":"D","voteCount":19600,"isWinner":true},{"candidateName":"Sophie Song","candidateIncumbent":false,"candidateParty":"R","voteCount":15954,"isWinner":false},{"candidateName":"Omar Din","candidateIncumbent":false,"candidateParty":"D","voteCount":8772,"isWinner":false},{"candidateName":"Bob Goodwyn","candidateIncumbent":false,"candidateParty":"Lib","voteCount":2170,"isWinner":false},{"candidateName":"Ashish Garg","candidateIncumbent":false,"candidateParty":"NPP","voteCount":1221,"isWinner":false}],"winnerDateTime":"2024-03-13T21:06:29.070Z"},"5989":{"id":"5989","type":"apRace","location":"State of California","raceName":"State House, District 28","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":0,"uncontested":true,"precinctsReportPercentage":0,"eevp":0,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"5:10 PM","source":"AP","candidates":[{"candidateName":"Gail Pellerin","candidateIncumbent":true,"candidateParty":"D","voteCount":0,"isWinner":true},{"candidateName":"Liz Lawler","candidateIncumbent":false,"candidateParty":"R","voteCount":0,"isWinner":true}],"winnerDateTime":"2024-03-06T04:00:30.000Z"},"6010":{"id":"6010","type":"apRace","location":"State of California","raceName":"State House, District 49","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":0,"uncontested":true,"precinctsReportPercentage":0,"eevp":0,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:36 PM","source":"AP","candidates":[{"candidateName":"Mike Fong","candidateIncumbent":true,"candidateParty":"D","voteCount":0,"isWinner":true},{"candidateName":"Long Liu","candidateIncumbent":false,"candidateParty":"R","voteCount":0,"isWinner":true}],"winnerDateTime":"2024-03-06T04:00:30.000Z"},"6018":{"id":"6018","type":"apRace","location":"State of California","raceName":"U.S. House of Representatives, District 2","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":229348,"precinctsReportPercentage":99.05,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:38 PM","source":"AP","candidates":[{"candidateName":"Jared Huffman","candidateIncumbent":true,"candidateParty":"D","voteCount":169005,"isWinner":true},{"candidateName":"Chris Coulombe","candidateIncumbent":false,"candidateParty":"R","voteCount":37372,"isWinner":true},{"candidateName":"Tief Gibbs","candidateIncumbent":false,"candidateParty":"R","voteCount":18437,"isWinner":false},{"candidateName":"Jolian Kangas","candidateIncumbent":false,"candidateParty":"NPP","voteCount":3166,"isWinner":false},{"candidateName":"Jason Brisendine","candidateIncumbent":false,"candidateParty":"NPP","voteCount":1368,"isWinner":false}],"winnerDateTime":"2024-03-12T00:46:10.103Z"},"6020":{"id":"6020","type":"apRace","location":"State of California","raceName":"U.S. House of Representatives, District 4","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":187640,"precinctsReportPercentage":96.32,"eevp":96.36,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Mike Thompson","candidateIncumbent":true,"candidateParty":"D","voteCount":118147,"isWinner":true},{"candidateName":"John Munn","candidateIncumbent":false,"candidateParty":"R","voteCount":56232,"isWinner":true},{"candidateName":"Andrew Engdahl","candidateIncumbent":false,"candidateParty":"D","voteCount":11202,"isWinner":false},{"candidateName":"Niket Patwardhan","candidateIncumbent":false,"candidateParty":"NPP","voteCount":2059,"isWinner":false}],"winnerDateTime":"2024-03-07T00:30:57.980Z"},"6025":{"id":"6025","type":"apRace","location":"State of California","raceName":"U.S. House of Representatives, District 9","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":121271,"precinctsReportPercentage":99.17,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"5:10 PM","source":"AP","candidates":[{"candidateName":"Josh Harder","candidateIncumbent":true,"candidateParty":"D","voteCount":60396,"isWinner":true},{"candidateName":"Kevin Lincoln","candidateIncumbent":false,"candidateParty":"R","voteCount":36346,"isWinner":true},{"candidateName":"John McBride","candidateIncumbent":false,"candidateParty":"R","voteCount":15525,"isWinner":false},{"candidateName":"Khalid Jafri","candidateIncumbent":false,"candidateParty":"R","voteCount":9004,"isWinner":false}],"winnerDateTime":"2024-03-12T00:49:44.113Z"},"6031":{"id":"6031","type":"apRace","location":"State of California","raceName":"U.S. House of Representatives, District 15","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":0,"uncontested":true,"precinctsReportPercentage":0,"eevp":0,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Anna Kramer","candidateIncumbent":false,"candidateParty":"R","voteCount":0,"isWinner":true},{"candidateName":"Kevin Mullin","candidateIncumbent":true,"candidateParty":"D","voteCount":0,"isWinner":true}],"winnerDateTime":"2024-03-06T04:00:30.000Z"},"6035":{"id":"6035","type":"apRace","location":"State of California","raceName":"U.S. House of Representatives, District 19","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":203670,"precinctsReportPercentage":99.11,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 25, 2024","timeUpdated":"5:47 AM","source":"AP","candidates":[{"candidateName":"Jimmy Panetta","candidateIncumbent":true,"candidateParty":"D","voteCount":132540,"isWinner":true},{"candidateName":"Jason Anderson","candidateIncumbent":false,"candidateParty":"R","voteCount":58120,"isWinner":true},{"candidateName":"Sean Dougherty","candidateIncumbent":false,"candidateParty":"Grn","voteCount":13010,"isWinner":false}],"winnerDateTime":"2024-03-07T00:23:46.779Z"},"6066":{"id":"6066","type":"apRace","location":"State of California","raceName":"State House, District 3","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":0,"uncontested":true,"precinctsReportPercentage":0,"eevp":0,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"5:10 PM","source":"AP","candidates":[{"candidateName":"Jamie Gallagher","candidateIncumbent":true,"candidateParty":"R","voteCount":0,"isWinner":true},{"candidateName":"Aaron Draper","candidateIncumbent":false,"candidateParty":"D","voteCount":0,"isWinner":true}],"winnerDateTime":"2024-03-06T04:00:30.000Z"},"6067":{"id":"6067","type":"apRace","location":"State of California","raceName":"State House, District 4","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":0,"uncontested":true,"precinctsReportPercentage":0,"eevp":0,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Cecilia Aguiar-Curry","candidateIncumbent":true,"candidateParty":"D","voteCount":0,"isWinner":true}],"winnerDateTime":"2024-03-06T04:00:30.000Z"},"6087":{"id":"6087","type":"apRace","location":"State of California","raceName":"State House, District 24","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":66643,"precinctsReportPercentage":99.19,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Alex Lee","candidateIncumbent":true,"candidateParty":"D","voteCount":45544,"isWinner":true},{"candidateName":"Bob Brunton","candidateIncumbent":false,"candidateParty":"R","voteCount":14951,"isWinner":true},{"candidateName":"Marti Souza","candidateIncumbent":false,"candidateParty":"R","voteCount":6148,"isWinner":false}],"winnerDateTime":"2024-03-14T23:23:49.770Z"},"6088":{"id":"6088","type":"apRace","location":"State of California","raceName":"State House, District 25","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":69560,"precinctsReportPercentage":99.31,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Ash Kalra","candidateIncumbent":true,"candidateParty":"D","voteCount":35821,"isWinner":true},{"candidateName":"Ted Stroll","candidateIncumbent":false,"candidateParty":"R","voteCount":18255,"isWinner":true},{"candidateName":"Lan Ngo","candidateIncumbent":false,"candidateParty":"D","voteCount":15484,"isWinner":false}],"winnerDateTime":"2024-03-14T02:40:57.200Z"},"6092":{"id":"6092","type":"apRace","location":"State of California","raceName":"State House, District 29","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":0,"uncontested":true,"precinctsReportPercentage":0,"eevp":0,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 25, 2024","timeUpdated":"5:47 AM","source":"AP","candidates":[{"candidateName":"Robert Rivas","candidateIncumbent":true,"candidateParty":"D","voteCount":0,"isWinner":true},{"candidateName":"J.W. Paine","candidateIncumbent":false,"candidateParty":"R","voteCount":0,"isWinner":true}],"winnerDateTime":"2024-03-06T04:00:30.000Z"},"6223":{"id":"6223","type":"apRace","location":"State of California","raceName":"U.S. House of Representatives, District 46","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":0,"uncontested":true,"precinctsReportPercentage":0,"eevp":0,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"5:16 PM","source":"AP","candidates":[{"candidateName":"Lou Correa","candidateIncumbent":true,"candidateParty":"D","voteCount":0,"isWinner":true},{"candidateName":"David Pan","candidateIncumbent":false,"candidateParty":"R","voteCount":0,"isWinner":true}],"winnerDateTime":"2024-03-06T04:00:30.000Z"},"6530":{"id":"6530","type":"apRace","location":"State of California","raceName":"State Senate, District 3","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":222193,"precinctsReportPercentage":98.99,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:48 PM","source":"AP","candidates":[{"candidateName":"Thom Bogue","candidateIncumbent":false,"candidateParty":"R","voteCount":61776,"isWinner":true},{"candidateName":"Christopher Cabaldon","candidateIncumbent":false,"candidateParty":"D","voteCount":59041,"isWinner":true},{"candidateName":"Rozzana Verder-Aliga","candidateIncumbent":false,"candidateParty":"D","voteCount":45546,"isWinner":false},{"candidateName":"Jackie Elward","candidateIncumbent":false,"candidateParty":"D","voteCount":41127,"isWinner":false},{"candidateName":"Jimih Jones","candidateIncumbent":false,"candidateParty":"R","voteCount":14703,"isWinner":false}],"winnerDateTime":"2024-03-15T01:24:31.539Z"},"6531":{"id":"6531","type":"apRace","location":"State of California","raceName":"State Senate, District 5","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":171623,"precinctsReportPercentage":99.09,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"5:10 PM","source":"AP","candidates":[{"candidateName":"Jim Shoemaker","candidateIncumbent":false,"candidateParty":"R","voteCount":74935,"isWinner":true},{"candidateName":"Jerry McNerney","candidateIncumbent":false,"candidateParty":"D","voteCount":57040,"isWinner":true},{"candidateName":"Carlos Villapudua","candidateIncumbent":false,"candidateParty":"D","voteCount":39648,"isWinner":false}],"winnerDateTime":"2024-03-13T20:07:46.382Z"},"6532":{"id":"6532","type":"apRace","location":"State of California","raceName":"State Senate, District 7","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":192446,"precinctsReportPercentage":98.72,"eevp":98.78,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:48 PM","source":"AP","candidates":[{"candidateName":"Jesse Arreguín","candidateIncumbent":false,"candidateParty":"D","voteCount":61837,"isWinner":true},{"candidateName":"Jovanka Beckles","candidateIncumbent":false,"candidateParty":"D","voteCount":34025,"isWinner":true},{"candidateName":"Dan Kalb","candidateIncumbent":false,"candidateParty":"D","voteCount":28842,"isWinner":false},{"candidateName":"Kathryn Lybarger","candidateIncumbent":false,"candidateParty":"D","voteCount":28041,"isWinner":false},{"candidateName":"Sandre Swanson","candidateIncumbent":false,"candidateParty":"D","voteCount":22862,"isWinner":false},{"candidateName":"Jeanne Solnordal","candidateIncumbent":false,"candidateParty":"R","voteCount":16839,"isWinner":false}],"winnerDateTime":"2024-03-16T00:58:11.533Z"},"6533":{"id":"6533","type":"apRace","location":"State of California","raceName":"State Senate, District 9","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":0,"uncontested":true,"precinctsReportPercentage":0,"eevp":0,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Tim Grayson","candidateIncumbent":false,"candidateParty":"D","voteCount":0,"isWinner":true},{"candidateName":"Marisol Rubio","candidateIncumbent":false,"candidateParty":"D","voteCount":0,"isWinner":true}],"winnerDateTime":"2024-03-06T04:00:30.000Z"},"6534":{"id":"6534","type":"apRace","location":"State of California","raceName":"State Senate, District 11","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":228260,"precinctsReportPercentage":99.09,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Scott Wiener","candidateIncumbent":true,"candidateParty":"D","voteCount":166592,"isWinner":true},{"candidateName":"Yvette Corkrean","candidateIncumbent":false,"candidateParty":"R","voteCount":34438,"isWinner":true},{"candidateName":"Cynthia Cravens","candidateIncumbent":false,"candidateParty":"D","voteCount":18513,"isWinner":false},{"candidateName":"Jing Xiong","candidateIncumbent":false,"candidateParty":"NPP","voteCount":8717,"isWinner":false}],"winnerDateTime":"2024-03-12T02:01:51.597Z"},"6535":{"id":"6535","type":"apRace","location":"State of California","raceName":"State Senate, District 13","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":227191,"precinctsReportPercentage":98.88,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Josh Becker","candidateIncumbent":true,"candidateParty":"D","voteCount":167127,"isWinner":true},{"candidateName":"Alexander Glew","candidateIncumbent":false,"candidateParty":"R","voteCount":42788,"isWinner":true},{"candidateName":"Christina Laskowski","candidateIncumbent":false,"candidateParty":"R","voteCount":17276,"isWinner":false}],"winnerDateTime":"2024-03-12T01:56:24.964Z"},"6536":{"id":"6536","type":"apRace","location":"State of California","raceName":"State Senate, District 15","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":180231,"precinctsReportPercentage":98.81,"eevp":98.95,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"4:20 PM","source":"AP","candidates":[{"candidateName":"Dave Cortese","candidateIncumbent":true,"candidateParty":"D","voteCount":124440,"isWinner":true},{"candidateName":"Robert Howell","candidateIncumbent":false,"candidateParty":"R","voteCount":34173,"isWinner":true},{"candidateName":"Tony Loaiza","candidateIncumbent":false,"candidateParty":"R","voteCount":21618,"isWinner":false}],"winnerDateTime":"2024-03-13T01:15:45.365Z"},"6548":{"id":"6548","type":"apRace","location":"State of California","raceName":"State Senate, District 39","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":0,"uncontested":true,"precinctsReportPercentage":0,"eevp":0,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 20, 2024","timeUpdated":"4:55 PM","source":"AP","candidates":[{"candidateName":"Akilah Weber","candidateIncumbent":false,"candidateParty":"D","voteCount":0,"isWinner":true},{"candidateName":"Bob Divine","candidateIncumbent":false,"candidateParty":"R","voteCount":0,"isWinner":true}],"winnerDateTime":"2024-03-06T04:00:30.000Z"},"6611":{"id":"6611","type":"apRace","location":"State of California","raceName":"U.S. House of Representatives, District 11","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":188732,"precinctsReportPercentage":98.89,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 22, 2024","timeUpdated":"8:25 AM","source":"AP","candidates":[{"candidateName":"Nancy Pelosi","candidateIncumbent":true,"candidateParty":"D","voteCount":138285,"isWinner":true},{"candidateName":"Bruce Lou","candidateIncumbent":false,"candidateParty":"R","voteCount":16285,"isWinner":true},{"candidateName":"Marjorie Mikels","candidateIncumbent":false,"candidateParty":"D","voteCount":9363,"isWinner":false},{"candidateName":"Bianca Von Krieg","candidateIncumbent":false,"candidateParty":"D","voteCount":7634,"isWinner":false},{"candidateName":"Jason Zeng","candidateIncumbent":false,"candidateParty":"R","voteCount":6607,"isWinner":false},{"candidateName":"Jason Boyce","candidateIncumbent":false,"candidateParty":"D","voteCount":4325,"isWinner":false},{"candidateName":"Larry Nichelson","candidateIncumbent":false,"candidateParty":"R","voteCount":3482,"isWinner":false},{"candidateName":"Eve Del Castello","candidateIncumbent":false,"candidateParty":"R","voteCount":2751,"isWinner":false}],"winnerDateTime":"2024-03-12T00:31:55.445Z"},"8589":{"id":"8589","type":"apRace","location":"State of California","raceName":"U.S. Senate, Class I","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":7276537,"precinctsReportPercentage":99,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 25, 2024","timeUpdated":"5:47 AM","source":"AP","candidates":[{"candidateName":"Adam Schiff","candidateIncumbent":false,"candidateParty":"D","voteCount":2299507,"isWinner":true},{"candidateName":"Steve Garvey","candidateIncumbent":false,"candidateParty":"R","voteCount":2292414,"isWinner":true},{"candidateName":"Katie Porter","candidateIncumbent":false,"candidateParty":"D","voteCount":1115606,"isWinner":false},{"candidateName":"Barbara Lee","candidateIncumbent":false,"candidateParty":"D","voteCount":714408,"isWinner":false},{"candidateName":"Eric Early","candidateIncumbent":false,"candidateParty":"R","voteCount":240723,"isWinner":false},{"candidateName":"James Bradley","candidateIncumbent":false,"candidateParty":"R","voteCount":98180,"isWinner":false},{"candidateName":"Christina Pascucci","candidateIncumbent":false,"candidateParty":"D","voteCount":61755,"isWinner":false},{"candidateName":"Sharleta Bassett","candidateIncumbent":false,"candidateParty":"R","voteCount":54422,"isWinner":false},{"candidateName":"Sarah Liew","candidateIncumbent":false,"candidateParty":"R","voteCount":38483,"isWinner":false},{"candidateName":"Laura Garza ","candidateIncumbent":false,"candidateParty":"NPP","voteCount":34320,"isWinner":false},{"candidateName":"Jonathan Reiss","candidateIncumbent":false,"candidateParty":"R","voteCount":34283,"isWinner":false},{"candidateName":"Sepi Gilani","candidateIncumbent":false,"candidateParty":"D","voteCount":34056,"isWinner":false},{"candidateName":"Gail Lightfoot","candidateIncumbent":false,"candidateParty":"Lib","voteCount":33046,"isWinner":false},{"candidateName":"Denice Gary-Pandol","candidateIncumbent":false,"candidateParty":"R","voteCount":25494,"isWinner":false},{"candidateName":"James Macauley","candidateIncumbent":false,"candidateParty":"R","voteCount":23168,"isWinner":false},{"candidateName":"Harmesh Kumar","candidateIncumbent":false,"candidateParty":"D","voteCount":21522,"isWinner":false},{"candidateName":"David Peterson","candidateIncumbent":false,"candidateParty":"D","voteCount":21076,"isWinner":false},{"candidateName":"Douglas Pierce","candidateIncumbent":false,"candidateParty":"D","voteCount":19371,"isWinner":false},{"candidateName":"Major Singh","candidateIncumbent":false,"candidateParty":"NPP","voteCount":16965,"isWinner":false},{"candidateName":"John Rose","candidateIncumbent":false,"candidateParty":"D","voteCount":14577,"isWinner":false},{"candidateName":"Perry Pound","candidateIncumbent":false,"candidateParty":"D","voteCount":14134,"isWinner":false},{"candidateName":"Raji Rab","candidateIncumbent":false,"candidateParty":"D","voteCount":13558,"isWinner":false},{"candidateName":"Mark Ruzon","candidateIncumbent":false,"candidateParty":"NPP","voteCount":13429,"isWinner":false},{"candidateName":"Forrest Jones","candidateIncumbent":false,"candidateParty":"AIP","voteCount":13027,"isWinner":false},{"candidateName":"Stefan Simchowitz","candidateIncumbent":false,"candidateParty":"R","voteCount":12717,"isWinner":false},{"candidateName":"Martin Veprauskas","candidateIncumbent":false,"candidateParty":"R","voteCount":9714,"isWinner":false},{"candidateName":"Don Grundmann","candidateIncumbent":false,"candidateParty":"NPP","voteCount":6582,"isWinner":false}],"winnerDateTime":"2024-03-06T05:01:46.589Z"},"8686":{"id":"8686","type":"apRace","location":"State of California","raceName":"President,","raceDescription":"Top candidate wins seat.","raceType":"top1","totalVotes":3589127,"precinctsReportPercentage":99,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 25, 2024","timeUpdated":"5:48 AM","source":"AP","candidates":[{"candidateName":"Joe Biden","candidateIncumbent":true,"candidateParty":"D","voteCount":3200188,"isWinner":true},{"candidateName":"Marianne Williamson","candidateIncumbent":false,"candidateParty":"D","voteCount":145690,"isWinner":false},{"candidateName":"Dean Phillips","candidateIncumbent":false,"candidateParty":"D","voteCount":99981,"isWinner":false},{"candidateName":"Armando Perez-Serrato","candidateIncumbent":false,"candidateParty":"D","voteCount":42925,"isWinner":false},{"candidateName":"Gabriel Cornejo","candidateIncumbent":false,"candidateParty":"D","voteCount":41261,"isWinner":false},{"candidateName":"President Boddie","candidateIncumbent":false,"candidateParty":"D","voteCount":25373,"isWinner":false},{"candidateName":"Stephen Lyons","candidateIncumbent":false,"candidateParty":"D","voteCount":21008,"isWinner":false},{"candidateName":"Eban Cambridge","candidateIncumbent":false,"candidateParty":"D","voteCount":12701,"isWinner":false}],"winnerDateTime":"2024-03-06T04:12:27.559Z"},"8688":{"id":"8688","type":"apRace","location":"State of California","raceName":"President,","raceDescription":"Top candidate wins seat.","raceType":"top1","totalVotes":2466569,"precinctsReportPercentage":99,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 25, 2024","timeUpdated":"5:47 AM","source":"AP","candidates":[{"candidateName":"Donald Trump","candidateIncumbent":false,"candidateParty":"R","voteCount":1953947,"isWinner":true},{"candidateName":"Nikki Haley","candidateIncumbent":false,"candidateParty":"R","voteCount":430792,"isWinner":false},{"candidateName":"Ron DeSantis","candidateIncumbent":false,"candidateParty":"R","voteCount":35581,"isWinner":false},{"candidateName":"Chris Christie","candidateIncumbent":false,"candidateParty":"R","voteCount":20164,"isWinner":false},{"candidateName":"Vivek Ramaswamy","candidateIncumbent":false,"candidateParty":"R","voteCount":11069,"isWinner":false},{"candidateName":"Rachel Swift","candidateIncumbent":false,"candidateParty":"R","voteCount":4231,"isWinner":false},{"candidateName":"David Stuckenberg","candidateIncumbent":false,"candidateParty":"R","voteCount":3895,"isWinner":false},{"candidateName":"Ryan Binkley","candidateIncumbent":false,"candidateParty":"R","voteCount":3563,"isWinner":false},{"candidateName":"Asa Hutchinson","candidateIncumbent":false,"candidateParty":"R","voteCount":3327,"isWinner":false}],"winnerDateTime":"2024-03-06T04:13:19.766Z"},"81993":{"id":"81993","type":"apRace","location":"State of California","raceName":"U.S. Senate, Class I Unexpired Term","raceDescription":"Top candidate wins seat.","raceType":"top2","totalVotes":7358837,"precinctsReportPercentage":99,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 25, 2024","timeUpdated":"5:47 AM","source":"AP","candidates":[{"candidateName":"Steve Garvey","candidateIncumbent":false,"candidateParty":"R","voteCount":2444940,"isWinner":true},{"candidateName":"Adam Schiff","candidateIncumbent":false,"candidateParty":"D","voteCount":2155146,"isWinner":true},{"candidateName":"Katie Porter","candidateIncumbent":false,"candidateParty":"D","voteCount":1269194,"isWinner":false},{"candidateName":"Barbara Lee","candidateIncumbent":false,"candidateParty":"D","voteCount":863278,"isWinner":false},{"candidateName":"Eric Early","candidateIncumbent":false,"candidateParty":"R","voteCount":448788,"isWinner":false},{"candidateName":"Christina Pascucci","candidateIncumbent":false,"candidateParty":"D","voteCount":109421,"isWinner":false},{"candidateName":"Sepi Gilani","candidateIncumbent":false,"candidateParty":"D","voteCount":68070,"isWinner":false}],"winnerDateTime":"2024-03-06T04:31:08.186Z"},"82014":{"id":"82014","type":"apRace","location":"State of California","raceName":"Proposition, 1 - Behavioral Health Services Program","raceDescription":"Top candidate wins seat.","raceType":"top1","totalVotes":7221972,"precinctsReportPercentage":99,"eevp":99,"tabulationStatus":"Tabulation Paused","dateUpdated":"March 25, 2024","timeUpdated":"5:47 AM","source":"AP","candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":null,"voteCount":3624998,"isWinner":true},{"candidateName":"No","candidateIncumbent":false,"candidateParty":null,"voteCount":3596974,"isWinner":false}],"winnerDateTime":"2024-03-21T00:11:06.265Z"},"timeLoaded":"April 19, 2024 4:44 AM","nationalRacesLoaded":true,"localRacesLoaded":true,"overrides":[{"id":"5921","raceName":"U.S. House of Representatives, District 7","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5922","raceName":"U.S. House of Representatives, District 8","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5924","raceName":"U.S. House of Representatives, District 10","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5926","raceName":"U.S. House of Representatives, District 12","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":"https://www.kqed.org/elections/results/alameda/congress-12th-district"},{"id":"5928","raceName":"U.S. House of Representatives, District 14","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5930","raceName":"U.S. House of Representatives, District 16","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":"https://www.kqed.org/elections/results/california/congress-16th-district"},{"id":"5931","raceName":"U.S. House of Representatives, District 17","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5932","raceName":"U.S. House of Representatives, District 18","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5963","raceName":"State Assembly, District 2","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5972","raceName":"State Assembly, District 11","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5973","raceName":"State Assembly, District 12","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5975","raceName":"State Assembly, District 14","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5976","raceName":"State Assembly, District 15","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":"https://www.kqed.org/elections/results/contracosta/state-assembly"},{"id":"5977","raceName":"State Assembly, District 16","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5978","raceName":"State Assembly, District 17","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5979","raceName":"State Assembly, District 18","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5980","raceName":"State Assembly, District 19","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5981","raceName":"State Assembly, District 20","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5982","raceName":"State Assembly, District 21","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"5984","raceName":"State Assembly, District 23","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":"https://www.kqed.org/elections/results/california/state-assembly-23rd-district"},{"id":"5987","raceName":"State Assembly, District 26","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":"https://www.kqed.org/elections/results/santaclara/state-assembly-26th-district"},{"id":"5989","raceName":"State Assembly, District 28","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6010","raceName":"State Assembly, District 4","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6018","raceName":"U.S. House of Representatives, District 2","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6020","raceName":"U.S. House of Representatives, District 4","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6025","raceName":"U.S. House of Representatives, District 9","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6031","raceName":"U.S. House of Representatives, District 15","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6035","raceName":"U.S. House of Representatives, District 19","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6067","raceName":"State Assembly, District 4","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6087","raceName":"State Assembly, District 24","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6088","raceName":"State Assembly, District 25","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6092","raceName":"State Assembly, District 29","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6223","raceName":"U.S. House of Representatives, District 4","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6530","raceName":"State Senate, District 3","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":"https://www.kqed.org/elections/results/california/state-senate-3rd-district"},{"id":"6531","raceName":"State Senate, District 5","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6532","raceName":"State Senate, District 7","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":"https://www.kqed.org/elections/results/california/state-senate-7th-district"},{"id":"6533","raceName":"State Senate, District 9","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6534","raceName":"State Senate, District 11","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6535","raceName":"State Senate, District 13","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6536","raceName":"State Senate, District 15","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"6611","raceName":"U.S. House of Representatives, District 11","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":""},{"id":"8589","raceName":"U.S. Senate (Full Term)","raceDescription":"Top two candidates advance to general election.","raceReadTheStory":"https://www.kqed.org/elections/results/california/senator"},{"id":"8686","raceName":"California Democratic Presidential Primary","raceDescription":"Candidates are competing for 496 delegates.","raceReadTheStory":"https://www.kqed.org/elections/results/president/democrat"},{"id":"8688","raceName":"California Republican Presidential Primary","raceDescription":"Candidates are competing for 169 delegates.","raceReadTheStory":"https://kqed.org/elections/results/president/republican"},{"id":"81993","raceName":"U.S. Senate (Partial/Unexpired Term)","raceDescription":"Top two candidates advance to general election."},{"id":"82014","raceName":"Proposition 1","raceDescription":"Bond and mental health reforms. Passes with majority vote.","raceReadTheStory":"https://www.kqed.org/elections/results/california/proposition-1"}],"AlamedaJudge5":{"id":"AlamedaJudge5","type":"localRace","location":"Alameda","raceName":"Superior Court Judge, Office 5","raceDescription":"Top candidate wins seat.","raceReadTheStory":"","raceType":"top1","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":200601,"candidates":[{"candidateName":"Terry Wiley","candidateIncumbent":true,"candidateParty":"","voteCount":200601}]},"AlamedaJudge12":{"id":"AlamedaJudge12","type":"localRace","location":"Alameda","raceName":"Superior Court Judge, Office 12","raceDescription":"Top candidate wins seat.","raceReadTheStory":"","raceType":"top1","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":240853,"candidates":[{"candidateName":"Mark Fickes","candidateIncumbent":false,"candidateParty":"","voteCount":133009},{"candidateName":"Michael P. Johnson","candidateIncumbent":false,"candidateParty":"","voteCount":107844}]},"AlamedaBoard2":{"id":"AlamedaBoard2","type":"localRace","location":"Alameda","raceName":"Board of Education, Trustee Area 2","raceDescription":"Top candidate wins seat.","raceReadTheStory":"","raceType":"top1","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":33580,"candidates":[{"candidateName":"John Lewis","candidateIncumbent":false,"candidateParty":"","voteCount":6943},{"candidateName":"Angela Normand","candidateIncumbent":true,"candidateParty":"","voteCount":26637}]},"AlamedaBoard5":{"id":"AlamedaBoard5","type":"localRace","location":"Alameda","raceName":"Board of Education, Trustee Area 5","raceDescription":"Top candidate wins seat.","raceReadTheStory":"","raceType":"top1","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":26072,"candidates":[{"candidateName":"Guadalupe \"Lupe\" Angulo","candidateIncumbent":false,"candidateParty":"","voteCount":7521},{"candidateName":"Janevette Cole","candidateIncumbent":true,"candidateParty":"","voteCount":13338},{"candidateName":"Joe Orlando Ramos","candidateIncumbent":false,"candidateParty":"","voteCount":5213}]},"AlamedaBoard6":{"id":"AlamedaBoard6","type":"localRace","location":"Alameda","raceName":"Board of Education, Trustee Area 6","raceDescription":"Top candidate wins seat.","raceReadTheStory":"","raceType":"top1","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":30864,"candidates":[{"candidateName":"John Guerrero","candidateIncumbent":false,"candidateParty":"","voteCount":9989},{"candidateName":"Eileen McDonald","candidateIncumbent":true,"candidateParty":"","voteCount":20875}]},"AlamedaSup1":{"id":"AlamedaSup1","type":"localRace","location":"Alameda","raceName":"Board of Supervisors, District 1","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":41038,"candidates":[{"candidateName":"David Haubert","candidateIncumbent":true,"candidateParty":"","voteCount":41038}]},"AlamedaSup2":{"id":"AlamedaSup2","type":"localRace","location":"Alameda","raceName":"Board of Supervisors, District 2","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top2","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":31034,"candidates":[{"candidateName":"Elisa Márquez","candidateIncumbent":true,"candidateParty":"","voteCount":31034}]},"AlamedaSup4":{"id":"AlamedaSup4","type":"localRace","location":"Alameda","raceName":"Board of Supervisors, District 4","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"https://www.kqed.org/elections/results/alameda/supervisor-4th-district","raceType":"top2","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":57007,"candidates":[{"candidateName":"Jennifer Esteen","candidateIncumbent":false,"candidateParty":"","voteCount":22400},{"candidateName":"Nate Miley","candidateIncumbent":true,"candidateParty":"","voteCount":34607}]},"AlamedaSup5":{"id":"AlamedaSup5","type":"localRace","location":"Alameda","raceName":"Board of Supervisors, District 5","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"https://www.kqed.org/elections/results/alameda/supervisor-5th-district","raceType":"top2","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":81059,"candidates":[{"candidateName":"Ben Bartlett","candidateIncumbent":false,"candidateParty":"","voteCount":13518},{"candidateName":"Nikki Fortunato Bas","candidateIncumbent":false,"candidateParty":"","voteCount":27597},{"candidateName":"John J. Bauters","candidateIncumbent":false,"candidateParty":"","voteCount":16783},{"candidateName":"Ken Berrick","candidateIncumbent":false,"candidateParty":"","voteCount":7520},{"candidateName":"Omar Farmer","candidateIncumbent":false,"candidateParty":"","voteCount":1240},{"candidateName":"Gregory Hodge","candidateIncumbent":false,"candidateParty":"","voteCount":3419},{"candidateName":"Chris Moore","candidateIncumbent":false,"candidateParty":"","voteCount":7428},{"candidateName":"Gerald Pechenuk","candidateIncumbent":false,"candidateParty":"","voteCount":305},{"candidateName":"Lorrel Plimier","candidateIncumbent":false,"candidateParty":"","voteCount":3249}]},"AlamedaBoard7":{"id":"AlamedaBoard7","type":"localRace","location":"Alameda","raceName":"Flood Control & Water Conservation District Director, Zone 7, Full Term","raceDescription":"Top three candidates win seat.","raceReadTheStory":"","raceType":"top3","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":134340,"candidates":[{"candidateName":"Alan Burnham","candidateIncumbent":false,"candidateParty":"","voteCount":15723},{"candidateName":"Sandy Figuers","candidateIncumbent":false,"candidateParty":"","voteCount":22454},{"candidateName":"Laurene K. Green","candidateIncumbent":false,"candidateParty":"","voteCount":30343},{"candidateName":"Kathy Narum","candidateIncumbent":true,"candidateParty":"","voteCount":23833},{"candidateName":"Seema Badar","candidateIncumbent":false,"candidateParty":"","voteCount":7468},{"candidateName":"Catherine Brown","candidateIncumbent":false,"candidateParty":"","voteCount":34519}]},"AlamedaAuditor":{"id":"AlamedaAuditor","type":"localRace","location":"Alameda","raceName":"Oakland Auditor","raceDescription":"Top candidate wins seat.","raceReadTheStory":"","raceType":"top1","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":59227,"candidates":[{"candidateName":"Michael Houston","candidateIncumbent":true,"candidateParty":"","voteCount":59227}]},"AlamedaMeasureA":{"id":"AlamedaMeasureA","type":"localRace","location":"Alameda","raceName":"Measure A","raceDescription":"Alameda County. Civil service. Passes with majority vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":282335,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":167903},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":114432}]},"AlamedaMeasureB":{"id":"AlamedaMeasureB","type":"localRace","location":"Alameda","raceName":"Measure B","raceDescription":"Alameda County. Recall rules. Passes with majority vote.","raceReadTheStory":"https://www.kqed.org/elections/results/alameda/measure-b","raceType":"yesNo","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":282683,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":182200},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":100483}]},"AlamedaMeasureD":{"id":"AlamedaMeasureD","type":"localRace","location":"Alameda","raceName":"Measure D","raceDescription":"Oakland. Appropriations limit. Passes with majority vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":79797,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":59852},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":19945}]},"AlamedaMeasureE":{"id":"AlamedaMeasureE","type":"localRace","location":"Alameda","raceName":"Measure E","raceDescription":"Alameda Unified School District. Parcel tax. Passes with 2/3 vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":22692,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":17280},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":5412}]},"AlamedaMeasureF":{"id":"AlamedaMeasureF","type":"localRace","location":"Alameda","raceName":"Measure F","raceDescription":"Piedmont. Parcel tax. Passes with 2/3 vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":4855,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":3673},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":1182}]},"AlamedaMeasureG":{"id":"AlamedaMeasureG","type":"localRace","location":"Alameda","raceName":"Measure G","raceDescription":"Albany Unified School District. Parcel tax. Passes with 2/3 vote. ","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":5898,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":4651},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":1247}]},"AlamedaMeasureH":{"id":"AlamedaMeasureH","type":"localRace","location":"Alameda","raceName":"Measure H","raceDescription":"Berkeley Unified School District. Parcel tax. Passes with 2/3 vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":33331,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":29418},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":3913}]},"AlamedaMeasureI":{"id":"AlamedaMeasureI","type":"localRace","location":"Alameda","raceName":"Measure I","raceDescription":"Hayward Unified School District. School bond. Passes with 55% vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":21929,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":14151},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":7778}]},"AlamedaMeasureJ":{"id":"AlamedaMeasureJ","type":"localRace","location":"Alameda","raceName":"Measure J","raceDescription":"San Leandro Unified School District. School bond. Passes with 55% vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"7:02 PM","dateUpdated":"April 1, 2024","totalVotes":12338,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":7784},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":4554}]},"CCD2":{"id":"CCD2","type":"localRace","location":"Contra Costa","raceName":"Board of Supervisors, District 2","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:45 PM","dateUpdated":"March 28, 2024","totalVotes":45776,"candidates":[{"candidateName":"Candace Andersen","candidateIncumbent":true,"candidateParty":"","voteCount":45776}]},"CCD3":{"id":"CCD3","type":"localRace","location":"Contra Costa","raceName":"Board of Supervisors, District 3","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"6:45 PM","dateUpdated":"March 28, 2024","totalVotes":25120,"candidates":[{"candidateName":"Diane Burgis","candidateIncumbent":true,"candidateParty":"","voteCount":25120}]},"CCD5":{"id":"CCD5","type":"localRace","location":"Contra Costa","raceName":"Board of Supervisors, District 5","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"https://www.kqed.org/elections/results/contracosta/supervisor-5th-district","raceType":"top2","timeUpdated":"6:45 PM","dateUpdated":"March 28, 2024","totalVotes":37045,"candidates":[{"candidateName":"Mike Barbanica","candidateIncumbent":false,"candidateParty":"","voteCount":14338},{"candidateName":"Jelani Killings","candidateIncumbent":false,"candidateParty":"","voteCount":5683},{"candidateName":"Shanelle Scales-Preston","candidateIncumbent":false,"candidateParty":"","voteCount":12993},{"candidateName":"Iztaccuauhtli Hector Gonzalez","candidateIncumbent":false,"candidateParty":"","voteCount":4031}]},"CCMeasureA":{"id":"CCMeasureA","type":"localRace","location":"Contra Costa","raceName":"Measure A","raceDescription":"Martinez. Appoint City Clerk. Passes with a majority vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:45 PM","dateUpdated":"March 28, 2024","totalVotes":11513,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":7554},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":3959}]},"CCMeasureB":{"id":"CCMeasureB","type":"localRace","location":"Contra Costa","raceName":"Measure B","raceDescription":"Antioch Unified School District. School bond. Passes with 55% vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:45 PM","dateUpdated":"March 28, 2024","totalVotes":17971,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":10397},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":7574}]},"CCMeasureC":{"id":"CCMeasureC","type":"localRace","location":"Contra Costa","raceName":"Measure C","raceDescription":"Martinez Unified School District. Parcel tax. Passes with 2/3 vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:45 PM","dateUpdated":"March 28, 2024","totalVotes":9230,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":6917},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":2313}]},"CCMeasureD":{"id":"CCMeasureD","type":"localRace","location":"Contra Costa","raceName":"Measure D","raceDescription":"Moraga School District. School bond. Passes with 55% vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:45 PM","dateUpdated":"March 28, 2024","totalVotes":6007,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":4052},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":1955}]},"MarinD2":{"id":"MarinD2","type":"localRace","location":"Marin","raceName":"Board of Supervisors, District 2","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"https://www.kqed.org/elections/results/marin/supervisor-2nd-district","raceType":"top2","timeUpdated":"6:54 PM","dateUpdated":"March 27, 2024","totalVotes":18466,"candidates":[{"candidateName":"Brian Colbert","candidateIncumbent":false,"candidateParty":"","voteCount":7971},{"candidateName":"Heather McPhail Sridharan","candidateIncumbent":false,"candidateParty":"","voteCount":4851},{"candidateName":"Ryan O'Neil","candidateIncumbent":false,"candidateParty":"","voteCount":2647},{"candidateName":"Gabe Paulson","candidateIncumbent":false,"candidateParty":"","voteCount":2997}]},"MarinD3":{"id":"MarinD3","type":"localRace","location":"Marin","raceName":"Board of Supervisors, District 3","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"6:54 PM","dateUpdated":"March 27, 2024","totalVotes":13274,"candidates":[{"candidateName":"Stephanie Moulton-Peters","candidateIncumbent":true,"candidateParty":"","voteCount":13274}]},"MarinD4":{"id":"MarinD4","type":"localRace","location":"Marin","raceName":"Board of Supervisors, District 4","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"6:54 PM","dateUpdated":"March 27, 2024","totalVotes":12986,"candidates":[{"candidateName":"Dennis Rodoni","candidateIncumbent":true,"candidateParty":"","voteCount":10086},{"candidateName":"Francis Drouillard","candidateIncumbent":false,"candidateParty":"","voteCount":2900}]},"MarinLarkspurCC":{"id":"MarinLarkspurCC","type":"localRace","location":"Marin","raceName":"Larkspur City Council (Short Term)","raceDescription":"Top candidate wins seat.","raceReadTheStory":"","raceType":"top1","timeUpdated":"6:54 PM","dateUpdated":"March 27, 2024","totalVotes":4176,"candidates":[{"candidateName":"Stephanie Andre","candidateIncumbent":false,"candidateParty":"","voteCount":2514},{"candidateName":"Claire Paquette","candidateIncumbent":false,"candidateParty":"","voteCount":1008},{"candidateName":"Lana Scott","candidateIncumbent":false,"candidateParty":"","voteCount":654}]},"MarinRossCouncil":{"id":"MarinRossCouncil","type":"localRace","location":"Marin","raceName":"Ross Town Council","raceDescription":"Top three candidates win seat.","raceReadTheStory":"","raceType":"top3","timeUpdated":"6:54 PM","dateUpdated":"March 27, 2024","totalVotes":1740,"candidates":[{"candidateName":"Charles William \"Bill\" Kircher, Jr.","candidateIncumbent":false,"candidateParty":"","voteCount":536},{"candidateName":"Mathew Salter","candidateIncumbent":false,"candidateParty":"","voteCount":502},{"candidateName":"Shadi Aboukhater","candidateIncumbent":false,"candidateParty":"","voteCount":187},{"candidateName":"Teri Dowling","candidateIncumbent":false,"candidateParty":"","voteCount":515}]},"MarinMeasureA":{"id":"MarinMeasureA","type":"localRace","location":"Marin","raceName":"Measure A","raceDescription":"Tamalpais Union High School District. School bond. Passes with 55% vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:54 PM","dateUpdated":"March 27, 2024","totalVotes":45345,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":24376},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":20969}]},"MarinMeasureB":{"id":"MarinMeasureB","type":"localRace","location":"Marin","raceName":"Measure B","raceDescription":"Petaluma Joint Union High School District. Parcel tax. Passes with 2/3 vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:54 PM","dateUpdated":"March 27, 2024","totalVotes":132,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":62},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":70}]},"MarinMeasureC":{"id":"MarinMeasureC","type":"localRace","location":"Marin","raceName":"Measure C","raceDescription":"Belvedere. Appropriation limit. Passes with majority vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:54 PM","dateUpdated":"March 27, 2024","totalVotes":870,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":679},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":191}]},"MarinMeasureD":{"id":"MarinMeasureD","type":"localRace","location":"Marin","raceName":"Measure D","raceDescription":"Larkspur. Rent stabilization. Passes with majority vote.","raceReadTheStory":"https://www.kqed.org/elections/results/marin/measure-d","raceType":"yesNo","timeUpdated":"6:54 PM","dateUpdated":"March 27, 2024","totalVotes":4955,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":2573},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":2382}]},"MarinMeasureE":{"id":"MarinMeasureE","type":"localRace","location":"Marin","raceName":"Measure E","raceDescription":"Ross. Special tax. Passes with 2/3 vote.","raceReadTheStory":"https://www.kqed.org/elections/results/marin/measure-e","raceType":"yesNo","timeUpdated":"6:54 PM","dateUpdated":"March 27, 2024","totalVotes":874,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":683},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":191}]},"MarinMeasureF":{"id":"MarinMeasureF","type":"localRace","location":"Marin","raceName":"Measure F","raceDescription":"San Anselmo. Flood Control and Water Conservation District. Passes with majority vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:54 PM","dateUpdated":"March 27, 2024","totalVotes":5193,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":3083},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":2110}]},"MarinMeasureG":{"id":"MarinMeasureG","type":"localRace","location":"Marin","raceName":"Measure G","raceDescription":"Bel Marin Keys Community Services District. Special tax. Passes with 2/3 vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:54 PM","dateUpdated":"March 27, 2024","totalVotes":830,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":661},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":169}]},"MarinMeasureH":{"id":"MarinMeasureH","type":"localRace","location":"Marin","raceName":"Measure H","raceDescription":"Marinwood Community Services District. Appropriations limit, fire protection. Passes with a majority vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:54 PM","dateUpdated":"March 27, 2024","totalVotes":1738,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":1369},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":369}]},"MarinMeasureI":{"id":"MarinMeasureI","type":"localRace","location":"Marin","raceName":"Measure I","raceDescription":"Marinwood Community Services District. Appropriations limit, parks. Passes with a majority vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:54 PM","dateUpdated":"March 27, 2024","totalVotes":1735,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":1336},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":399}]},"NapaD2":{"id":"NapaD2","type":"localRace","location":"Napa","raceName":"Board of Supervisors, District 2","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"6:50 PM","dateUpdated":"April 3, 2024","totalVotes":8351,"candidates":[{"candidateName":"Liz Alessio","candidateIncumbent":false,"candidateParty":"","voteCount":6340},{"candidateName":"Doris Gentry","candidateIncumbent":false,"candidateParty":"","voteCount":2011}]},"NapaD4":{"id":"NapaD4","type":"localRace","location":"Napa","raceName":"Board of Supervisors, District 4","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"https://www.kqed.org/elections/results/napa/supervisor-4th-district","raceType":"top1","timeUpdated":"6:50 PM","dateUpdated":"April 3, 2024","totalVotes":7306,"candidates":[{"candidateName":"Amber Manfree","candidateIncumbent":false,"candidateParty":"","voteCount":3913},{"candidateName":"Pete Mott","candidateIncumbent":false,"candidateParty":"","voteCount":3393}]},"NapaD5":{"id":"NapaD5","type":"localRace","location":"Napa","raceName":"Board of Supervisors, District 5","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"https://www.kqed.org/elections/results/napa/supervisor-5th-district","raceType":"top1","timeUpdated":"6:50 PM","dateUpdated":"April 3, 2024","totalVotes":5356,"candidates":[{"candidateName":"Mariam Aboudamous","candidateIncumbent":false,"candidateParty":"","voteCount":2379},{"candidateName":"Belia Ramos","candidateIncumbent":true,"candidateParty":"","voteCount":2977}]},"NapaMeasureD":{"id":"NapaMeasureD","type":"localRace","location":"Napa","raceName":"Measure D","raceDescription":"Howell Mountain Elementary School District. School bond. Passes with 55% vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:50 PM","dateUpdated":"April 3, 2024","totalVotes":741,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":367},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":374}]},"NapaMeasureU":{"id":"NapaMeasureU","type":"localRace","location":"Napa","raceName":"Measure U","raceDescription":"Lake Berryessa Resort Improvement District. Appropriations limit. Passes with majority vote. ","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:50 PM","dateUpdated":"April 3, 2024","totalVotes":86,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":63},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":23}]},"NapaMeasureU1":{"id":"NapaMeasureU1","type":"localRace","location":"Napa","raceName":"Measure U","raceDescription":"Yountville. Appropriations limit. Passes with majority vote. ","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:50 PM","dateUpdated":"April 3, 2024","totalVotes":925,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":793},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":132}]},"SFJudge1":{"id":"SFJudge1","type":"localRace","location":"San Francisco","raceName":"Superior Court Judge, Seat 1","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"https://www.kqed.org/elections/results/sanfrancisco/superior-court-seat-1","raceType":"top1","timeUpdated":"6:50 PM","dateUpdated":"March 21, 2024","totalVotes":202960,"candidates":[{"candidateName":"Michael Begert","candidateIncumbent":true,"candidateParty":"","voteCount":124943},{"candidateName":"Chip Zecher","candidateIncumbent":false,"candidateParty":"","voteCount":78017}]},"SFJudge13":{"id":"SFJudge13","type":"localRace","location":"San Francisco","raceName":"Superior Court Judge, Seat 13","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"https://www.kqed.org/elections/results/sanfrancisco/superior-court-seat-13","raceType":"top1","timeUpdated":"6:50 PM","dateUpdated":"March 21, 2024","totalVotes":202386,"candidates":[{"candidateName":"Jean Myungjin Roland","candidateIncumbent":false,"candidateParty":"","voteCount":90012},{"candidateName":"Patrick S. Thompson","candidateIncumbent":true,"candidateParty":"","voteCount":112374}]},"SFPropA":{"id":"SFPropA","type":"localRace","location":"San Francisco","raceName":"Proposition A","raceDescription":"Housing bond. Passes with 2/3 vote.","raceReadTheStory":"https://www.kqed.org/elections/results/sanfrancisco/proposition-a","raceType":"yesNo","timeUpdated":"6:50 PM","dateUpdated":"March 21, 2024","totalVotes":225187,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":158497},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":66690}]},"SFPropB":{"id":"SFPropB","type":"localRace","location":"San Francisco","raceName":"Proposition B","raceDescription":"Police staffing. Passes with majority vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:50 PM","dateUpdated":"March 21, 2024","totalVotes":222954,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":61580},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":161374}]},"SFPropC":{"id":"SFPropC","type":"localRace","location":"San Francisco","raceName":"Proposition C","raceDescription":"Transfer tax exemption. Passes with majority vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:50 PM","dateUpdated":"March 21, 2024","totalVotes":220349,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":116311},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":104038}]},"SFPropD":{"id":"SFPropD","type":"localRace","location":"San Francisco","raceName":"Proposition D","raceDescription":"Ethics laws. Passes with majority vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:50 PM","dateUpdated":"March 21, 2024","totalVotes":222615,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":198584},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":24031}]},"SFPropE":{"id":"SFPropE","type":"localRace","location":"San Francisco","raceName":"Proposition E","raceDescription":"Police policies. Passes with majority vote.","raceReadTheStory":"https://www.kqed.org/elections/results/sanfrancisco/proposition-e","raceType":"yesNo","timeUpdated":"6:50 PM","dateUpdated":"March 21, 2024","totalVotes":222817,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":120529},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":102288}]},"SFPropF":{"id":"SFPropF","type":"localRace","location":"San Francisco","raceName":"Proposition F","raceDescription":"Drug screening. Passes with majority vote.","raceReadTheStory":"https://www.kqed.org/elections/results/sanfrancisco/proposition-f","raceType":"yesNo","timeUpdated":"6:50 PM","dateUpdated":"March 21, 2024","totalVotes":224004,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":130214},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":93790}]},"SFPropG":{"id":"SFPropG","type":"localRace","location":"San Francisco","raceName":"Proposition G","raceDescription":"Eighth-grade algebra. Passes with majority vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:50 PM","dateUpdated":"March 21, 2024","totalVotes":222704,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":182066},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":40638}]},"SMJudge4":{"id":"SMJudge4","type":"localRace","location":"San Mateo","raceName":"Superior Court Judge, Office 4","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"6:56 PM","dateUpdated":"April 4, 2024","totalVotes":108919,"candidates":[{"candidateName":"Sarah Burdick","candidateIncumbent":false,"candidateParty":"","voteCount":108919}]},"SMD1":{"id":"SMD1","type":"localRace","location":"San Mateo","raceName":"Board of Supervisors, District 1","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"https://www.kqed.org/elections/results/sanmateo/supervisor-1st-district","raceType":"top1","timeUpdated":"6:56 PM","dateUpdated":"April 4, 2024","totalVotes":29650,"candidates":[{"candidateName":"Jackie Speier","candidateIncumbent":false,"candidateParty":"","voteCount":20353},{"candidateName":"Ann Schneider","candidateIncumbent":false,"candidateParty":"","voteCount":9297}]},"SMD4":{"id":"SMD4","type":"localRace","location":"San Mateo","raceName":"Board of Supervisors, District 4","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"https://www.kqed.org/elections/results/sanmateo/supervisor-4th-district","raceType":"top2","timeUpdated":"6:56 PM","dateUpdated":"April 4, 2024","totalVotes":22725,"candidates":[{"candidateName":"Antonio Lopez","candidateIncumbent":false,"candidateParty":"","voteCount":5730},{"candidateName":"Lisa Gauthier","candidateIncumbent":false,"candidateParty":"","voteCount":10358},{"candidateName":"Celeste Brevard","candidateIncumbent":false,"candidateParty":"","voteCount":1268},{"candidateName":"Paul Bocanegra","candidateIncumbent":false,"candidateParty":"","voteCount":1909},{"candidateName":"Maggie Cornejo","candidateIncumbent":false,"candidateParty":"","voteCount":3460}]},"SMD5":{"id":"SMD5","type":"localRace","location":"San Mateo","raceName":"Board of Supervisors, District 5","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"6:56 PM","dateUpdated":"April 4, 2024","totalVotes":19937,"candidates":[{"candidateName":"David Canepa","candidateIncumbent":true,"candidateParty":"","voteCount":19937}]},"SMMeasureB":{"id":"SMMeasureB","type":"localRace","location":"San Mateo","raceName":"Measure B","raceDescription":"County Service Area #1 (Highlands). Special tax. Passes with 2/3 vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:56 PM","dateUpdated":"April 4, 2024","totalVotes":1549,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":1360},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":189}]},"SMMeasureC":{"id":"SMMeasureC","type":"localRace","location":"San Mateo","raceName":"Measure C","raceDescription":"Jefferson Elementary School District. Parcel tax. Passes with 2/3 vote","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:56 PM","dateUpdated":"April 4, 2024","totalVotes":12234,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":8543},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":3691}]},"SMMeasureE":{"id":"SMMeasureE","type":"localRace","location":"San Mateo","raceName":"Measure E","raceDescription":"Woodside Elementary School District. School bond. Passes with 55% vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:56 PM","dateUpdated":"April 4, 2024","totalVotes":1392,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":910},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":482}]},"SMMeasureG":{"id":"SMMeasureG","type":"localRace","location":"San Mateo","raceName":"Measure G","raceDescription":"Pacifica School District. School bond. Passes with 55% vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:56 PM","dateUpdated":"April 4, 2024","totalVotes":11548,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":7067},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":4481}]},"SMMeasureH":{"id":"SMMeasureH","type":"localRace","location":"San Mateo","raceName":"Measure H","raceDescription":"San Carlos School District. School bond. Passes with 55% vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:56 PM","dateUpdated":"April 4, 2024","totalVotes":9938,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":6283},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":3655}]},"SCJudge5":{"id":"SCJudge5","type":"localRace","location":"Santa Clara","raceName":"Superior Court Judge, Office 5","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"7:05 PM","dateUpdated":"April 4, 2024","totalVotes":301953,"candidates":[{"candidateName":"Jay Boyarsky","candidateIncumbent":false,"candidateParty":"","voteCount":142549},{"candidateName":"Nicole M. Ford","candidateIncumbent":false,"candidateParty":"","voteCount":52147},{"candidateName":"Johnene Linda Stebbins","candidateIncumbent":false,"candidateParty":"","voteCount":107257}]},"SCD2":{"id":"SCD2","type":"localRace","location":"Santa Clara","raceName":"Board of Supervisors, District 2","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"https://www.kqed.org/elections/results/santaclara/supervisor-2nd-district","raceType":"top2","timeUpdated":"7:05 PM","dateUpdated":"April 4, 2024","totalVotes":44059,"candidates":[{"candidateName":"Corina Herrera-Loera","candidateIncumbent":false,"candidateParty":"","voteCount":10519},{"candidateName":"Jennifer Margaret Celaya","candidateIncumbent":false,"candidateParty":"","voteCount":2394},{"candidateName":"Madison Nguyen","candidateIncumbent":false,"candidateParty":"","voteCount":12794},{"candidateName":"Betty Duong","candidateIncumbent":false,"candidateParty":"","voteCount":14031},{"candidateName":"Nelson McElmurry","candidateIncumbent":false,"candidateParty":"","voteCount":4321}]},"SCD3":{"id":"SCD3","type":"localRace","location":"Santa Clara","raceName":"Board of Supervisors, District 3","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"7:05 PM","dateUpdated":"April 4, 2024","totalVotes":42549,"candidates":[{"candidateName":"Otto Lee","candidateIncumbent":true,"candidateParty":"","voteCount":42549}]},"SCD5":{"id":"SCD5","type":"localRace","location":"Santa Clara","raceName":"Board of Supervisors, District 5","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"https://www.kqed.org/elections/results/santaclara/supervisor-5th-district","raceType":"top2","timeUpdated":"7:05 PM","dateUpdated":"April 4, 2024","totalVotes":88712,"candidates":[{"candidateName":"Margaret Abe-Koga","candidateIncumbent":false,"candidateParty":"","voteCount":37172},{"candidateName":"Sally J. Lieber","candidateIncumbent":false,"candidateParty":"","voteCount":21962},{"candidateName":"Barry Chang","candidateIncumbent":false,"candidateParty":"","voteCount":6164},{"candidateName":"Peter C. Fung","candidateIncumbent":false,"candidateParty":"","voteCount":17892},{"candidateName":"Sandy Sans","candidateIncumbent":false,"candidateParty":"","voteCount":5522}]},"SCSJMayor":{"id":"SCSJMayor","type":"localRace","location":"Santa Clara","raceName":"San José Mayor","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"7:05 PM","dateUpdated":"April 4, 2024","totalVotes":167064,"candidates":[{"candidateName":"Matt Mahan","candidateIncumbent":true,"candidateParty":"","voteCount":144701},{"candidateName":"Tyrone Wade","candidateIncumbent":false,"candidateParty":"","voteCount":22363}]},"SCSJD2":{"id":"SCSJD2","type":"localRace","location":"Santa Clara","raceName":"San José City Council, District 2","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top2","timeUpdated":"7:05 PM","dateUpdated":"April 4, 2024","totalVotes":14131,"candidates":[{"candidateName":"Joe Lopez","candidateIncumbent":false,"candidateParty":"","voteCount":4950},{"candidateName":"Pamela Campos","candidateIncumbent":false,"candidateParty":"","voteCount":3436},{"candidateName":"Vanessa Sandoval","candidateIncumbent":false,"candidateParty":"","voteCount":2719},{"candidateName":"Babu Prasad","candidateIncumbent":false,"candidateParty":"","voteCount":3026}]},"SCSJD4":{"id":"SCSJD4","type":"localRace","location":"Santa Clara","raceName":"San José City Council, District 4","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"7:05 PM","dateUpdated":"April 4, 2024","totalVotes":14322,"candidates":[{"candidateName":"Kansen Chu","candidateIncumbent":false,"candidateParty":"","voteCount":5931},{"candidateName":"David Cohen","candidateIncumbent":true,"candidateParty":"","voteCount":8391}]},"SCSJD6":{"id":"SCSJD6","type":"localRace","location":"Santa Clara","raceName":"San José City Council, District 6","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top2","timeUpdated":"7:05 PM","dateUpdated":"April 4, 2024","totalVotes":25108,"candidates":[{"candidateName":"David Cohen","candidateIncumbent":false,"candidateParty":"","voteCount":9875},{"candidateName":"Alex Shoor","candidateIncumbent":false,"candidateParty":"","voteCount":3850},{"candidateName":"Angelo \"A.J.\" Pasciuti","candidateIncumbent":false,"candidateParty":"","voteCount":2688},{"candidateName":"Michael Mulcahy","candidateIncumbent":false,"candidateParty":"","voteCount":8695}]},"SCSJD8":{"id":"SCSJD8","type":"localRace","location":"Santa Clara","raceName":"San José City Council, District 8","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top2","timeUpdated":"7:05 PM","dateUpdated":"April 4, 2024","totalVotes":21462,"candidates":[{"candidateName":"Tam Truong","candidateIncumbent":false,"candidateParty":"","voteCount":6982},{"candidateName":"Domingo Candelas","candidateIncumbent":true,"candidateParty":"","voteCount":8466},{"candidateName":"Sukhdev Singh Bainiwal","candidateIncumbent":false,"candidateParty":"","voteCount":5513},{"candidateName":"Surinder Kaur Dhaliwal","candidateIncumbent":false,"candidateParty":"","voteCount":501}]},"SCSJD10":{"id":"SCSJD10","type":"localRace","location":"Santa Clara","raceName":"San José City Council, District 10","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top2","timeUpdated":"7:05 PM","dateUpdated":"April 4, 2024","totalVotes":22799,"candidates":[{"candidateName":"George Casey","candidateIncumbent":false,"candidateParty":"","voteCount":8805},{"candidateName":"Arjun Batra","candidateIncumbent":true,"candidateParty":"","voteCount":8354},{"candidateName":"Lenka Wright","candidateIncumbent":false,"candidateParty":"","voteCount":5640}]},"SCMeasureA":{"id":"SCMeasureA","type":"localRace","location":"Santa Clara","raceName":"Measure A","raceDescription":"Santa Clara. Appointed city clerk. Passes with majority vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"7:05 PM","dateUpdated":"April 4, 2024","totalVotes":20315,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":6580},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":13735}]},"SCMeasureB":{"id":"SCMeasureB","type":"localRace","location":"Santa Clara","raceName":"Measure B","raceDescription":"Santa Clara. Appointed police chief. Passes with majority vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"7:05 PM","dateUpdated":"April 4, 2024","totalVotes":20567,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":5680},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":14887}]},"SCMeasureC":{"id":"SCMeasureC","type":"localRace","location":"Santa Clara","raceName":"Measure C","raceDescription":"Sunnyvale School District. School bond. Passes with 55% vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"7:05 PM","dateUpdated":"April 4, 2024","totalVotes":14656,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":10261},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":4395}]},"SolanoD15":{"id":"SolanoD15","type":"localRace","location":"Solano","raceName":"Superior Court Judge, Department 15","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"","timeUpdated":"7:08 PM","dateUpdated":"March 28, 2024","totalVotes":81709,"candidates":[{"candidateName":"Mike Thompson","candidateIncumbent":false,"candidateParty":"","voteCount":36844},{"candidateName":"Bryan J. Kim","candidateIncumbent":false,"candidateParty":"","voteCount":44865}]},"SolanoD1":{"id":"SolanoD1","type":"localRace","location":"Solano","raceName":"Board of Supervisors, District 1","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"https://www.kqed.org/elections/results/solano/supervisor-1st-district","raceType":"","timeUpdated":"7:08 PM","dateUpdated":"March 28, 2024","totalVotes":13786,"candidates":[{"candidateName":"Michael Wilson","candidateIncumbent":false,"candidateParty":"","voteCount":6401},{"candidateName":"Cassandra James","candidateIncumbent":false,"candidateParty":"","voteCount":7385}]},"SolanoD2":{"id":"SolanoD2","type":"localRace","location":"Solano","raceName":"Board of Supervisors, District 2","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"","timeUpdated":"7:08 PM","dateUpdated":"March 28, 2024","totalVotes":19903,"candidates":[{"candidateName":"Monica Brown","candidateIncumbent":true,"candidateParty":"","voteCount":10951},{"candidateName":"Nora Dizon","candidateIncumbent":false,"candidateParty":"","voteCount":3135},{"candidateName":"Rochelle Sherlock","candidateIncumbent":false,"candidateParty":"","voteCount":5817}]},"SolanoD5":{"id":"SolanoD5","type":"localRace","location":"Solano","raceName":"Board of Supervisors, District 5","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"","timeUpdated":"7:08 PM","dateUpdated":"March 28, 2024","totalVotes":17888,"candidates":[{"candidateName":"Mitch Mashburn","candidateIncumbent":true,"candidateParty":"","voteCount":11210},{"candidateName":"Chadwick J. Ledoux","candidateIncumbent":false,"candidateParty":"","voteCount":6678}]},"SolanoEducation":{"id":"SolanoEducation","type":"localRace","location":"Solano","raceName":"Sacramento County Board of Education","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"","timeUpdated":"7:08 PM","dateUpdated":"March 28, 2024","totalVotes":3650,"candidates":[{"candidateName":"Heather Davis","candidateIncumbent":true,"candidateParty":"","voteCount":2960},{"candidateName":"Shazleen Khan","candidateIncumbent":false,"candidateParty":"","voteCount":690}]},"SolanoMeasureA":{"id":"SolanoMeasureA","type":"localRace","location":"Solano","raceName":"Measure A","raceDescription":"Benicia. Hotel tax. Passes with majority vote.","raceReadTheStory":"https://www.kqed.org/elections/results/solano/measure-a","raceType":"yesNo","timeUpdated":"7:08 PM","dateUpdated":"March 28, 2024","totalVotes":10136,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":7869},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":2267}]},"SolanoMeasureB":{"id":"SolanoMeasureB","type":"localRace","location":"Solano","raceName":"Measure B","raceDescription":"Benicia. Sales tax. Passes with majority vote.","raceReadTheStory":"https://www.kqed.org/elections/results/solano/measure-b","raceType":"yesNo","timeUpdated":"7:08 PM","dateUpdated":"March 28, 2024","totalVotes":10164,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":7335},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":2829}]},"SolanoMeasureC":{"id":"SolanoMeasureC","type":"localRace","location":"Solano","raceName":"Measure C","raceDescription":"Benicia Unified School District. School bond. Passes with 55% vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"7:08 PM","dateUpdated":"March 28, 2024","totalVotes":10112,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":6316},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":3796}]},"SolanoMeasureN":{"id":"SolanoMeasureN","type":"localRace","location":"Solano","raceName":"Measure N","raceDescription":"Davis Joint Unified School District. Parcel tax. Passes with 2/3 vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"7:08 PM","dateUpdated":"March 28, 2024","totalVotes":15,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":5},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":10}]},"SonomaJudge3":{"id":"SonomaJudge3","type":"localRace","location":"Sonoma","raceName":"Superior Court Judge, Office 3","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"6:51 PM","dateUpdated":"March 29, 2024","totalVotes":115405,"candidates":[{"candidateName":"Kristine M. Burk","candidateIncumbent":false,"candidateParty":"","voteCount":79498},{"candidateName":"Beki Berrey","candidateIncumbent":false,"candidateParty":"","voteCount":35907}]},"SonomaJudge4":{"id":"SonomaJudge4","type":"localRace","location":"Sonoma","raceName":"Superior Court Judge, Office 4","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"6:51 PM","dateUpdated":"March 29, 2024","totalVotes":86789,"candidates":[{"candidateName":"Paul J. Lozada","candidateIncumbent":false,"candidateParty":"","voteCount":86789}]},"SonomaJudge6":{"id":"SonomaJudge6","type":"localRace","location":"Sonoma","raceName":"Superior Court Judge, Office 6","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"6:51 PM","dateUpdated":"March 29, 2024","totalVotes":117990,"candidates":[{"candidateName":"Omar Figueroa","candidateIncumbent":false,"candidateParty":"","voteCount":42236},{"candidateName":"Kenneth English","candidateIncumbent":false,"candidateParty":"","voteCount":75754}]},"SonomaD1":{"id":"SonomaD1","type":"localRace","location":"Sonoma","raceName":"Board of Supervisors, District 1","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"6:51 PM","dateUpdated":"March 29, 2024","totalVotes":30348,"candidates":[{"candidateName":"Rebecca Hermosillo","candidateIncumbent":false,"candidateParty":"","voteCount":23958},{"candidateName":"Jonathan Mathieu","candidateIncumbent":false,"candidateParty":"","voteCount":6390}]},"SonomaD3":{"id":"SonomaD3","type":"localRace","location":"Sonoma","raceName":"Board of Supervisors, District 3","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"https://www.kqed.org/elections/results/sonoma/supervisor-3rd-district","raceType":"top1","timeUpdated":"6:51 PM","dateUpdated":"March 29, 2024","totalVotes":16312,"candidates":[{"candidateName":"Chris Coursey","candidateIncumbent":true,"candidateParty":"","voteCount":11346},{"candidateName":"Omar Medina","candidateIncumbent":false,"candidateParty":"","voteCount":4966}]},"SonomaD5":{"id":"SonomaD5","type":"localRace","location":"Sonoma","raceName":"Board of Supervisors, District 5","raceDescription":"Candidate with majority vote wins seat. If no candidate reaches majority, top two candidates advance to runoff in general election.","raceReadTheStory":"","raceType":"top1","timeUpdated":"6:51 PM","dateUpdated":"March 29, 2024","totalVotes":23356,"candidates":[{"candidateName":"Lynda Hopkins","candidateIncumbent":true,"candidateParty":"","voteCount":23356}]},"SonomaMeasureA":{"id":"SonomaMeasureA","type":"localRace","location":"Sonoma","raceName":"Measure A","raceDescription":"Cotati-Rohnert Park Unified School District. Parcel tax. Passes with 2/3 vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:51 PM","dateUpdated":"March 29, 2024","totalVotes":13756,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":10320},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":3436}]},"SonomaMeasureB":{"id":"SonomaMeasureB","type":"localRace","location":"Sonoma","raceName":"Measure B","raceDescription":"Petaluma Joint Union High School District. Parcel tax. Passes with 2/3 vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:51 PM","dateUpdated":"March 29, 2024","totalVotes":24877,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":15795},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":9082}]},"SonomaMeasureC":{"id":"SonomaMeasureC","type":"localRace","location":"Sonoma","raceName":"Measure C","raceDescription":"Fort Ross School District. School bond. Passes with 55% vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:51 PM","dateUpdated":"March 29, 2024","totalVotes":286,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":159},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":127}]},"SonomaMeasureD":{"id":"SonomaMeasureD","type":"localRace","location":"Sonoma","raceName":"Measure D","raceDescription":"Harmony Union School District. School bond. Passes with 55% vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:51 PM","dateUpdated":"March 29, 2024","totalVotes":1925,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":1089},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":836}]},"SonomaMeasureE":{"id":"SonomaMeasureE","type":"localRace","location":"Sonoma","raceName":"Measure E","raceDescription":"Petaluma City (Elementary) School District. Parcel tax. Passes with 2/3 vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:51 PM","dateUpdated":"March 29, 2024","totalVotes":11133,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":7622},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":3511}]},"SonomaMeasureG":{"id":"SonomaMeasureG","type":"localRace","location":"Sonoma","raceName":"Measure G","raceDescription":"Rincon Valley Union School District. School bond. Passes with 55% vote.","raceReadTheStory":"","raceType":"yesNo","timeUpdated":"6:51 PM","dateUpdated":"March 29, 2024","totalVotes":14577,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":8668},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":5909}]},"SonomaMeasureH":{"id":"SonomaMeasureH","type":"localRace","location":"Sonoma","raceName":"Measure H","raceDescription":"Sonoma County. Sales tax. Passes with majority vote.","raceReadTheStory":"https://www.kqed.org/elections/results/sonoma/measure-h","raceType":"yesNo","timeUpdated":"6:51 PM","dateUpdated":"March 29, 2024","totalVotes":145261,"candidates":[{"candidateName":"Yes","candidateIncumbent":false,"candidateParty":"","voteCount":89646},{"candidateName":"No","candidateIncumbent":false,"candidateParty":"","voteCount":55615}]}},"radioSchedulesReducer":{},"listsReducer":{"posts/science?tag=hiv":{"isFetching":false,"latestQuery":{"from":0,"postsToRender":9},"tag":null,"vitalsOnly":true,"totalRequested":6,"isLoading":false,"isLoadingMore":false,"total":6,"items":["science_1966675","science_1952464","science_1944497","science_1938724","science_1934916","science_8108"]}},"recallGuideReducer":{"intros":{},"policy":{},"candidates":{}},"savedPostsReducer":{},"pfsSessionReducer":{},"siteSettingsReducer":{},"subscriptionsReducer":{},"termsReducer":{"about":{"name":"About","type":"terms","id":"about","slug":"about","link":"/about","taxonomy":"site"},"arts":{"name":"Arts & Culture","grouping":["arts","pop","trulyca"],"description":"KQED Arts provides daily in-depth coverage of the Bay Area's music, art, film, performing arts, literature and arts news, as well as cultural commentary and criticism.","type":"terms","id":"arts","slug":"arts","link":"/arts","taxonomy":"site"},"artschool":{"name":"Art School","parent":"arts","type":"terms","id":"artschool","slug":"artschool","link":"/artschool","taxonomy":"site"},"bayareabites":{"name":"KQED food","grouping":["food","bayareabites","checkplease"],"parent":"food","type":"terms","id":"bayareabites","slug":"bayareabites","link":"/food","taxonomy":"site"},"bayareahiphop":{"name":"Bay Area Hiphop","type":"terms","id":"bayareahiphop","slug":"bayareahiphop","link":"/bayareahiphop","taxonomy":"site"},"campaign21":{"name":"Campaign 21","type":"terms","id":"campaign21","slug":"campaign21","link":"/campaign21","taxonomy":"site"},"checkplease":{"name":"KQED food","grouping":["food","bayareabites","checkplease"],"parent":"food","type":"terms","id":"checkplease","slug":"checkplease","link":"/food","taxonomy":"site"},"education":{"name":"Education","grouping":["education"],"type":"terms","id":"education","slug":"education","link":"/education","taxonomy":"site"},"elections":{"name":"Elections","type":"terms","id":"elections","slug":"elections","link":"/elections","taxonomy":"site"},"events":{"name":"Events","type":"terms","id":"events","slug":"events","link":"/events","taxonomy":"site"},"event":{"name":"Event","alias":"events","type":"terms","id":"event","slug":"event","link":"/event","taxonomy":"site"},"filmschoolshorts":{"name":"Film School Shorts","type":"terms","id":"filmschoolshorts","slug":"filmschoolshorts","link":"/filmschoolshorts","taxonomy":"site"},"food":{"name":"KQED food","grouping":["food","bayareabites","checkplease"],"type":"terms","id":"food","slug":"food","link":"/food","taxonomy":"site"},"forum":{"name":"Forum","relatedContentQuery":"posts/forum?","parent":"news","type":"terms","id":"forum","slug":"forum","link":"/forum","taxonomy":"site"},"futureofyou":{"name":"Future of You","grouping":["science","futureofyou"],"parent":"science","type":"terms","id":"futureofyou","slug":"futureofyou","link":"/futureofyou","taxonomy":"site"},"jpepinheart":{"name":"KQED food","relatedContentQuery":"trending/food,bayareabites,checkplease","parent":"food","type":"terms","id":"jpepinheart","slug":"jpepinheart","link":"/food","taxonomy":"site"},"liveblog":{"name":"Live Blog","type":"terms","id":"liveblog","slug":"liveblog","link":"/liveblog","taxonomy":"site"},"livetv":{"name":"Live TV","parent":"tv","type":"terms","id":"livetv","slug":"livetv","link":"/livetv","taxonomy":"site"},"lowdown":{"name":"The Lowdown","relatedContentQuery":"posts/lowdown?","parent":"news","type":"terms","id":"lowdown","slug":"lowdown","link":"/lowdown","taxonomy":"site"},"mindshift":{"name":"Mindshift","parent":"news","description":"MindShift explores the future of education by highlighting the innovative – and sometimes counterintuitive – ways educators and parents are helping all children succeed.","type":"terms","id":"mindshift","slug":"mindshift","link":"/mindshift","taxonomy":"site"},"news":{"name":"News","grouping":["news","forum"],"type":"terms","id":"news","slug":"news","link":"/news","taxonomy":"site"},"perspectives":{"name":"Perspectives","parent":"radio","type":"terms","id":"perspectives","slug":"perspectives","link":"/perspectives","taxonomy":"site"},"podcasts":{"name":"Podcasts","type":"terms","id":"podcasts","slug":"podcasts","link":"/podcasts","taxonomy":"site"},"pop":{"name":"Pop","parent":"arts","type":"terms","id":"pop","slug":"pop","link":"/pop","taxonomy":"site"},"pressroom":{"name":"Pressroom","type":"terms","id":"pressroom","slug":"pressroom","link":"/pressroom","taxonomy":"site"},"quest":{"name":"Quest","parent":"science","type":"terms","id":"quest","slug":"quest","link":"/quest","taxonomy":"site"},"radio":{"name":"Radio","grouping":["forum","perspectives"],"description":"Listen to KQED Public Radio – home of Forum and The California Report – on 88.5 FM in San Francisco, 89.3 FM in Sacramento, 88.3 FM in Santa Rosa and 88.1 FM in Martinez.","type":"terms","id":"radio","slug":"radio","link":"/radio","taxonomy":"site"},"root":{"name":"KQED","image":"https://ww2.kqed.org/app/uploads/2020/02/KQED-OG-Image@1x.png","imageWidth":1200,"imageHeight":630,"headData":{"title":"KQED | News, Radio, Podcasts, TV | Public Media for Northern California","description":"KQED provides public radio, television, and independent reporting on issues that matter to the Bay Area. We’re the NPR and PBS member station for Northern California."},"type":"terms","id":"root","slug":"root","link":"/root","taxonomy":"site"},"science":{"name":"Science","grouping":["science","futureofyou"],"description":"KQED Science brings you award-winning science and environment coverage from the Bay Area and beyond.","type":"terms","id":"science","slug":"science","link":"/science","taxonomy":"site"},"stateofhealth":{"name":"State of Health","parent":"science","type":"terms","id":"stateofhealth","slug":"stateofhealth","link":"/stateofhealth","taxonomy":"site"},"support":{"name":"Support","type":"terms","id":"support","slug":"support","link":"/support","taxonomy":"site"},"thedolist":{"name":"The Do List","parent":"arts","type":"terms","id":"thedolist","slug":"thedolist","link":"/thedolist","taxonomy":"site"},"trulyca":{"name":"Truly CA","grouping":["arts","pop","trulyca"],"parent":"arts","type":"terms","id":"trulyca","slug":"trulyca","link":"/trulyca","taxonomy":"site"},"tv":{"name":"TV","type":"terms","id":"tv","slug":"tv","link":"/tv","taxonomy":"site"},"voterguide":{"name":"Voter Guide","parent":"elections","alias":"elections","type":"terms","id":"voterguide","slug":"voterguide","link":"/voterguide","taxonomy":"site"},"science_660":{"type":"terms","id":"science_660","meta":{"index":"terms_1591234321","site":"science","id":"660","found":true},"relationships":{},"included":{},"name":"HIV","slug":"hiv","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"HIV Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null,"imageData":{"ogImageSize":{"file":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png","width":1200,"height":630},"twImageSize":{"file":"https://cdn.kqed.org/wp-content/uploads/2020/02/KQED-OG-Image@1x.png"},"twitterCard":"summary_large_image"}},"ttid":666,"isLoading":false,"link":"/science/tag/hiv"},"source_science_1966675":{"type":"terms","id":"source_science_1966675","meta":{"override":true},"name":"Coronavirus","isLoading":false},"source_science_1952464":{"type":"terms","id":"source_science_1952464","meta":{"override":true},"name":"Discoveries and Trends","isLoading":false},"source_science_1944497":{"type":"terms","id":"source_science_1944497","meta":{"override":true},"name":"PBS Newshour","isLoading":false},"source_science_1938724":{"type":"terms","id":"source_science_1938724","meta":{"override":true},"name":"STAT","isLoading":false},"source_science_1934916":{"type":"terms","id":"source_science_1934916","meta":{"override":true},"name":"NPR","link":"https://www.npr.org/sections/health-shots/2018/11/26/670752865/chinese-scientist-says-hes-first-to-genetically-edit-babies","isLoading":false},"science_39":{"type":"terms","id":"science_39","meta":{"index":"terms_1591234321","site":"science","id":"39","found":true},"relationships":{},"included":{},"name":"Health","slug":"health","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Health Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":41,"isLoading":false,"link":"/science/category/health"},"science_4550":{"type":"terms","id":"science_4550","meta":{"index":"terms_1591234321","site":"science","id":"4550","found":true},"relationships":{},"included":{},"name":"Local","slug":"local","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Local Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":4550,"isLoading":false,"link":"/science/category/local"},"science_3890":{"type":"terms","id":"science_3890","meta":{"index":"terms_1591234321","site":"science","id":"3890","found":true},"relationships":{},"included":{},"name":"Medical Science","slug":"medical-science","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Medical Science Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":3890,"isLoading":false,"link":"/science/category/medical-science"},"science_40":{"type":"terms","id":"science_40","meta":{"index":"terms_1591234321","site":"science","id":"40","found":true},"relationships":{},"included":{},"name":"News","slug":"news","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"News Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":42,"isLoading":false,"link":"/science/category/news"},"science_4450":{"type":"terms","id":"science_4450","meta":{"index":"terms_1591234321","site":"science","id":"4450","found":true},"relationships":{},"included":{},"name":"Science","slug":"science","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Science Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":4450,"isLoading":false,"link":"/science/category/science"},"science_4329":{"type":"terms","id":"science_4329","meta":{"index":"terms_1591234321","site":"science","id":"4329","found":true},"relationships":{},"included":{},"name":"Coronavirus","slug":"coronavirus","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"Coronavirus Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":4329,"isLoading":false,"link":"/science/tag/coronavirus"},"science_4417":{"type":"terms","id":"science_4417","meta":{"index":"terms_1591234321","site":"science","id":"4417","found":true},"relationships":{},"included":{},"name":"featured-news","slug":"featured-news","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"featured-news Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":4417,"isLoading":false,"link":"/science/tag/featured-news"},"science_4414":{"type":"terms","id":"science_4414","meta":{"index":"terms_1591234321","site":"science","id":"4414","found":true},"relationships":{},"included":{},"name":"featured-science","slug":"featured-science","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"featured-science Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":4414,"isLoading":false,"link":"/science/tag/featured-science"},"science_5181":{"type":"terms","id":"science_5181","meta":{"index":"terms_1591234321","site":"science","id":"5181","found":true},"relationships":{},"included":{},"name":"health","slug":"health","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"health Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":5181,"isLoading":false,"link":"/science/tag/health"},"science_28":{"type":"terms","id":"science_28","meta":{"index":"terms_1591234321","site":"science","id":"28","found":true},"relationships":{},"included":{},"name":"Astronomy","slug":"astronomy","taxonomy":"category","description":"Explore the universe with KQED Science! Dive into the latest astronomy news, discover celestial events, and unravel the mysteries of outer space.","featImg":null,"headData":{"title":"Astronomy Articles | KQED Science","description":"Explore the universe with KQED Science! Dive into the latest astronomy news, discover celestial events, and unravel the mysteries of outer space.","ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":30,"isLoading":false,"link":"/science/category/astronomy"},"science_30":{"type":"terms","id":"science_30","meta":{"index":"terms_1591234321","site":"science","id":"30","found":true},"relationships":{},"included":{},"name":"Biology","slug":"biology","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Biology Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":32,"isLoading":false,"link":"/science/category/biology"},"science_29":{"type":"terms","id":"science_29","meta":{"index":"terms_1591234321","site":"science","id":"29","found":true},"relationships":{},"included":{},"name":"Chemistry","slug":"chemistry","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Chemistry Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":31,"isLoading":false,"link":"/science/category/chemistry"},"science_31":{"type":"terms","id":"science_31","meta":{"index":"terms_1591234321","site":"science","id":"31","found":true},"relationships":{},"included":{},"name":"Climate","slug":"climate","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Climate Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":33,"isLoading":false,"link":"/science/category/climate"},"science_33":{"type":"terms","id":"science_33","meta":{"index":"terms_1591234321","site":"science","id":"33","found":true},"relationships":{},"included":{},"name":"Energy","slug":"energy","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Energy Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":35,"isLoading":false,"link":"/science/category/energy"},"science_35":{"type":"terms","id":"science_35","meta":{"index":"terms_1591234321","site":"science","id":"35","found":true},"relationships":{},"included":{},"name":"Environment","slug":"environment","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Environment Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":37,"isLoading":false,"link":"/science/category/environment"},"science_2873":{"type":"terms","id":"science_2873","meta":{"index":"terms_1591234321","site":"science","id":"2873","found":true},"relationships":{},"included":{},"name":"Oceans","slug":"oceans","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Oceans Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":2873,"isLoading":false,"link":"/science/category/oceans"},"science_42":{"type":"terms","id":"science_42","meta":{"index":"terms_1591234321","site":"science","id":"42","found":true},"relationships":{},"included":{},"name":"Physics","slug":"physics","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Physics Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":44,"isLoading":false,"link":"/science/category/physics"},"science_3423":{"type":"terms","id":"science_3423","meta":{"index":"terms_1591234321","site":"science","id":"3423","found":true},"relationships":{},"included":{},"name":"Science Podcast","slug":"science-podcast","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Bay Area Science: Stories & Insights with KQED's Science Podcasts","description":"Our captivating podcasts take you on a journey through the Bay Area's vibrant scientific landscape. Discover groundbreaking research & hear expert insights.","ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null,"socialTitle":"Bay Area Science: Stories & Insights with KQED's Science Podcasts"},"ttid":3423,"isLoading":false,"link":"/science/category/science-podcast"},"science_3947":{"type":"terms","id":"science_3947","meta":{"index":"terms_1591234321","site":"science","id":"3947","found":true},"relationships":{},"included":{},"name":"Space","slug":"space","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Space Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":3947,"isLoading":false,"link":"/science/category/space"},"science_3730":{"type":"terms","id":"science_3730","meta":{"index":"terms_1591234321","site":"science","id":"3730","found":true},"relationships":{},"included":{},"name":"Wildfires","slug":"wildfires","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Wildfires Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":3730,"isLoading":false,"link":"/science/category/wildfires"},"science_194":{"type":"terms","id":"science_194","meta":{"index":"terms_1591234321","site":"science","id":"194","found":true},"relationships":{},"included":{},"name":"climate change","slug":"climate-change","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"climate change Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":198,"isLoading":false,"link":"/science/tag/climate-change"},"science_134":{"type":"terms","id":"science_134","meta":{"index":"terms_1591234321","site":"science","id":"134","found":true},"relationships":{},"included":{},"name":"energy","slug":"energy-2","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"energy Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":138,"isLoading":false,"link":"/science/tag/energy-2"},"science_3370":{"type":"terms","id":"science_3370","meta":{"index":"terms_1591234321","site":"science","id":"3370","found":true},"relationships":{},"included":{},"name":"featured","slug":"featured","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"featured Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":3370,"isLoading":false,"link":"/science/tag/featured"},"science_4154":{"type":"terms","id":"science_4154","meta":{"index":"terms_1591234321","site":"science","id":"4154","found":true},"relationships":{},"included":{},"name":"Medical science","slug":"medical-science","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"Medical science Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":4154,"isLoading":false,"link":"/science/tag/medical-science"},"science_672":{"type":"terms","id":"science_672","meta":{"index":"terms_1591234321","site":"science","id":"672","found":true},"relationships":{},"included":{},"name":"physics","slug":"physics-2","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"physics Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":678,"isLoading":false,"link":"/science/tag/physics-2"},"science_309":{"type":"terms","id":"science_309","meta":{"index":"terms_1591234321","site":"science","id":"309","found":true},"relationships":{},"included":{},"name":"science","slug":"science","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"science Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":314,"isLoading":false,"link":"/science/tag/science"},"science_577":{"type":"terms","id":"science_577","meta":{"index":"terms_1591234321","site":"science","id":"577","found":true},"relationships":{},"included":{},"name":"space","slug":"space","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"space Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":583,"isLoading":false,"link":"/science/tag/space"},"science_113":{"type":"terms","id":"science_113","meta":{"index":"terms_1591234321","site":"science","id":"113","found":true},"relationships":{},"included":{},"name":"wildfire","slug":"wildfire","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"wildfire Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":117,"isLoading":false,"link":"/science/tag/wildfire"},"science_2874":{"type":"terms","id":"science_2874","meta":{"index":"terms_1591234321","site":"science","id":"2874","found":true},"relationships":{},"included":{},"name":"Animals","slug":"animals","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Animals Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":2874,"isLoading":false,"link":"/science/category/animals"},"science_1287":{"type":"terms","id":"science_1287","meta":{"index":"terms_1591234321","site":"science","id":"1287","found":true},"relationships":{},"included":{},"name":"CRISPR","slug":"crispr","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"CRISPR Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":1296,"isLoading":false,"link":"/science/tag/crispr"},"science_3838":{"type":"terms","id":"science_3838","meta":{"index":"terms_1591234321","site":"science","id":"3838","found":true},"relationships":{},"included":{},"name":"ingest","slug":"ingest","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"ingest Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":3838,"isLoading":false,"link":"/science/tag/ingest"},"science_3151":{"type":"terms","id":"science_3151","meta":{"index":"terms_1591234321","site":"science","id":"3151","found":true},"relationships":{},"included":{},"name":"Future of You","slug":"future-of-you","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"Future of You Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":3151,"isLoading":false,"link":"/science/category/future-of-you"},"science_3424":{"type":"terms","id":"science_3424","meta":{"index":"terms_1591234321","site":"science","id":"3424","found":true},"relationships":{},"included":{},"name":"KQED Future of You","slug":"kqed-future-of-you","taxonomy":"category","description":null,"featImg":null,"headData":{"title":"KQED Future of You Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":3424,"isLoading":false,"link":"/science/category/kqed-future-of-you"},"science_664":{"type":"terms","id":"science_664","meta":{"index":"terms_1591234321","site":"science","id":"664","found":true},"relationships":{},"included":{},"name":"disease","slug":"disease","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"disease Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":670,"isLoading":false,"link":"/science/tag/disease"},"science_305":{"type":"terms","id":"science_305","meta":{"index":"terms_1591234321","site":"science","id":"305","found":true},"relationships":{},"included":{},"name":"DNA","slug":"dna","taxonomy":"tag","description":null,"featImg":null,"headData":{"title":"DNA Archives | KQED Science","description":null,"ogTitle":null,"ogDescription":null,"ogImgId":null,"twTitle":null,"twDescription":null,"twImgId":null},"ttid":310,"isLoading":false,"link":"/science/tag/dna"}},"userAgentReducer":{"userAgent":"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)","isBot":true},"userPermissionsReducer":{"wpLoggedIn":false},"localStorageReducer":{},"browserHistoryReducer":[],"eventsReducer":{},"fssReducer":{},"tvDailyScheduleReducer":{},"tvWeeklyScheduleReducer":{},"tvPrimetimeScheduleReducer":{},"tvMonthlyScheduleReducer":{},"userAccountReducer":{"routeTo":"","showDeleteConfirmModal":false,"user":{"userId":"","isFound":false,"firstName":"","lastName":"","phoneNumber":"","email":"","articles":[]}},"youthMediaReducer":{},"checkPleaseReducer":{"filterData":{},"restaurantData":[]},"reframeReducer":{"attendee":null},"location":{"pathname":"/science/tag/hiv/","previousPathname":"/"}}